| Sku |
AAP31048 |
| Old sku |
AAPP24027 |
| Price |
$99.00 |
| Name |
STAT6 Peptide (AAP31048) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
STAT6 |
| Alias symbols |
D12S1644, IL-4-STAT, STAT6B, STAT6C |
| Gene id |
6778 |
| Description of target |
Full-length human STAR6 (NP_003144) was expressed in E.coli as inclusion body and purified after protein refolding for mouse immunization. Clone 5B1 shows excellent western blot detection of endogenous STAT6 using ACHN cell lysate.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P42226 |
| Protein accession num |
NP_003144 |
| Nucleotide accession num |
NM_003153 |
| Protein size |
847 amino acids |
| Molecular weight |
94kDa |
| Application |
IHC, WB |
| Partner proteins |
IL4R,NMI,STAT6,CEBPB,CREBBP,EP300,ETS1,HIST2H3C,IL4R,IRF4,JAK1,NCOA1,NFKB1,NMI,PRKCZ,PTPN6,RELA,SND1,SRC,STAT2,STAT6,ANXA2,CREBBP,EP300,IRF4,NCOA1,NFKB1,SND1,TP53 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Li,B.H., (2008) Biochem. Biophys. Res. Commun. 369 (2), 554-560 |
| Description |
This is a synthetic peptide designed for use in combination with anti-STAT6 antibody (Catalog #: ARP31048_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
