ELOA Peptide - C-terminal region (AAP31037)

Data Sheet
 
Sku AAP31037
Old sku AAPP01770
Price $99.00
Name ELOA Peptide - C-terminal region (AAP31037)
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Size 100 ug
Gene ELOA
Alias symbols SIII, TCEB3, TCEB3A, SIII p110
Gene id 6924
Description of target This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Swissprot id Q14241
Protein accession num NP_003189
Nucleotide accession num NM_003198
Protein size 772 amino acids
Molecular weight 87kDa
Application IHC, WB
Partner proteins KRTAP10-3; CEP57L1; SPERT; FAM9B; KRT40; CEP70; GMCL1; HOMEZ; TRIM54; MID2; PLK4; JAKMIP2; PSMB9; POLR2L; POLR2K; POLR2J; POLR2I; POLR2H; POLR2G; POLR2F; POLR2E; POLR2D; POLR2C; POLR2B; POLR2A; MDFI; UBC; RAD54B; MED26; ECT2; BARD1; CDK12; TCEB2; TCEB1; B
Quality control The peptide is characterized by mass spectroscopy
Key reference Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Description This is a synthetic peptide designed for use in combination with anti-TCEB3 antibody (Catalog #: P100692_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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