| Sku |
AAP31019 |
| Old sku |
AAPP01752 |
| Price |
$99.00 |
| Name |
NFX1 Peptide - middle region (AAP31019) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NFX1 |
| Alias symbols |
DKFZp779G2416, MGC20369, NFX2 |
| Gene id |
4799 |
| Description of target |
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. |
| Swissprot id |
Q12986 |
| Protein accession num |
NP_002495 |
| Nucleotide accession num |
NM_002504 |
| Protein size |
1120 amino acids |
| Molecular weight |
124kDa |
| Application |
IHC, WB |
| Partner proteins |
ELAVL4,NUP153,NUP214,NUP62,NUP98 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Katzenellenbogen,R.A., (2007) J. Virol. 81 (8), 3786-3796 |
| Description |
This is a synthetic peptide designed for use in combination with anti-NFX1 antibody (Catalog #: P100680_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
