| Sku |
AAP30957 |
| Old sku |
AAPP36421 |
| Price |
$99.00 |
| Name |
SMAD6 Peptide (AAP30957) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
SMAD6 |
| Alias symbols |
HsT17432, MADH6, MADH7 |
| Gene id |
4091 |
| Description of target |
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. |
| Swissprot id |
O43541 |
| Protein accession num |
NP_005576 |
| Nucleotide accession num |
NM_005585 |
| Protein size |
496 amino acids |
| Molecular weight |
53kDa |
| Application |
WB |
| Partner proteins |
BMPR1B,HOXC8,MAP3K7,RNF111,RUNX2,SMAD1,SMAD7,SMURF1,SMURF2,STAMBP,STRAP,TAB1,TGFBR1,TOB1,CTBP1,HOXC8,MAP3K7,PIAS4,RNF111,SMAD1,SMAD2,SMAD4,SMAD7,STAMBP,STRAP,TAB1,YAP1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Tsunobuchi,H., et al., (2004) Biophys. Res. Commun. 316 (3), 712-719 |
| Description |
This is a synthetic peptide designed for use in combination with anti-SMAD6 antibody (Catalog #: P100717_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
