Sku |
AAP30916 |
Old sku |
AAPP01640 |
Price |
$99.00 |
Name |
FOS Peptide - middle region (AAP30916) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
FOS |
Alias symbols |
c-fos, p55, AP-1, C-FOS |
Gene id |
2353 |
Description of target |
The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The family members are leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P01100 |
Protein accession num |
NP_005243 |
Nucleotide accession num |
NM_005252 |
Protein size |
380 amino acids |
Molecular weight |
41kDa |
Application |
WB |
Partner proteins |
EGFR,STAT3,ELK4,SRF,KHSRP,JAG1,JUN,JUN,RELA,ATF2,ATF7,BATF,BCL3,CEBPG,COBRA1,CSNK2A1,CSNK2A2,DDIT3,EEF1D,ELK1,ELK4,EPHB2,ETS1,FOS,GATA4,GTF2F2,HNF1A,JUN,JUNB,JUND,LMNA,MAF,MAP3K7,MAPK1,MITF,NCOA1,NCOR2,NFATC3,NFKB1,OPTN,PRKACA,PSMC5,RB1,RELA,RPS6KA1,RPS6KA4,RUNX1,RUNX2,SCHIP1,SMAD3,SMARCD1,STAT1,SUMO1,SUMO2,SUMO3,SUMO4,TAF1,TBP,TRO,TSC22D3,USF2,WDR65,XBP1,ATF2,BCL3,COBRA1,CREBBP,CSNK2A1,CSNK2A2,DDIT3,ETS2,GTF2E2,GTF2F1,GTF2F2,HNF1A,JUN,JUND,MAPK1,MITF,NACA,NCOA1,NCOA6,NCOR2,PML,RELA,RPS6KA2,RPS6KA4,RUNX1,RUNX2,SMAD3,SPI1,TAF1,TBP,TSC22D3,VDR,XBP1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Seldeen,K.L., (2008) Arch. Biochem. Biophys. 473 (1), 48-60 |
Description |
This is a synthetic peptide designed for use in combination with anti-FOS antibody (Catalog #: P100626_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |
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