FOS Peptide (AAP30915)

Data Sheet
 
Sku AAP30915
Old sku AAPP01639
Price $99.00
Name FOS Peptide (AAP30915)
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Size 100 ug
Gene FOS
Alias symbols p55, AP-1, C-FOS
Gene id 2353
Description of target The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Swissprot id P01100
Protein accession num NP_005243
Nucleotide accession num NM_005252
Protein size 380 amino acids
Molecular weight 41kDa
Application WB
Partner proteins EGFR,STAT3,ELK4,SRF,KHSRP,JAG1,JUN,JUN,RELA,ATF2,ATF7,BATF,BCL3,CEBPG,COBRA1,CSNK2A1,CSNK2A2,DDIT3,EEF1D,ELK1,ELK4,EPHB2,ETS1,FOS,GATA4,GTF2F2,HNF1A,JUN,JUNB,JUND,LMNA,MAF,MAP3K7,MAPK1,MITF,NCOA1,NCOR2,NFATC3,NFKB1,OPTN,PRKACA,PSMC5,RB1,RELA,RPS6KA1,RPS6KA4,RUNX1,RUNX2,SCHIP1,SMAD3,SMARCD1,STAT1,SUMO1,SUMO2,SUMO3,SUMO4,TAF1,TBP,TRO,TSC22D3,USF2,WDR65,XBP1,ATF2,BCL3,COBRA1,CREBBP,CSNK2A1,CSNK2A2,DDIT3,ETS2,GTF2E2,GTF2F1,GTF2F2,HNF1A,JUN,JUND,MAPK1,MITF,NACA,NCOA1,NCOA6,NCOR2,PML,RELA,RPS6KA2,RPS6KA4,RUNX1,RUNX2,SMAD3,SPI1,TAF1,TBP,TSC22D3,VDR,XBP1
Quality control The peptide is characterized by mass spectroscopy
Key reference Pan,X., et al., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1052-1058
Description This is a synthetic peptide designed for use in combination with anti-FOS antibody (Catalog #: P100639_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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