CCL8 Peptide - middle region (AAP30808)

Data Sheet
 
Sku AAP30808
Old sku AAPP01471
Price $99.00
Name CCL8 Peptide - middle region (AAP30808)
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Size 100 ug
Gene CCL8
Alias symbols HC14, MCP-2, MCP2, SCYA10, SCYA8
Gene id 6355
Description of target CCL8 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P80075
Protein accession num NP_005614
Nucleotide accession num NM_005623
Protein size 99 amino acids
Molecular weight 9kDa
Application WB
Partner proteins CCBP2,CCR1,CCR2,CCR3,CCR5,CCRL1,DARC,MMP3,VCAN,CCBP2,VCAN
Quality control The peptide is characterized by mass spectroscopy
Key reference Hori,T., (2008) Blood 111 (8), 4403-4412
Description This is a synthetic peptide designed for use in combination with anti-CCL8 antibody (Catalog #: AVARP07026_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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