CCR4 Peptide - middle region (AAP30786)

Data Sheet
 
Sku AAP30786
Old sku AAPP01449
Price $99.00
Name CCR4 Peptide - middle region (AAP30786)
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Size 100 ug
Gene CCR4
Alias symbols CC-CKR-4, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293, CD194
Gene id 1233
Description of target CCR4 belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1657 BC071751.1 1-1657
Swissprot id P51679
Protein accession num NP_005499
Nucleotide accession num NM_005508
Protein size 360 amino acids
Molecular weight 41kDa
Application WB
Partner proteins ADRBK1,ADRBK2,CCL17,CCL22,CCL3,CCL5,ADRBK1,ADRBK2,CCL22,CCL3,CCL5
Quality control The peptide is characterized by mass spectroscopy
Key reference Nakayama,T., (2008) Oncogene 27 (23), 3221-3232
Description This is a synthetic peptide designed for use in combination with anti-CCR4 antibody (Catalog #: AVARP07017_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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