| Sku |
AAP30724 |
| Old sku |
AAPP01381 |
| Price |
$99.00 |
| Name |
NAPA Peptide (AAP30724) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NAPA |
| Alias symbols |
SNAPA |
| Gene id |
8775 |
| Description of target |
The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. |
| Swissprot id |
P54920 |
| Protein accession num |
NP_003818 |
| Nucleotide accession num |
NM_003827 |
| Protein size |
295 amino acids |
| Molecular weight |
33kDa |
| Application |
WB |
| Partner proteins |
TRPC3,BNIP1,GNA12,GOSR1,GOSR2,NSF,RTN4,SNAP23,STX12,STX1A,STX4,STX5,STX7,STX8,TRPC3,VAMP8,NSF,RTN4,SNAP23,SNAP25,STX12,STX1A,STX4,STX5,STX7,STX8,VAMP2,VAMP8 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Lemons, P.P., et al., (1997) Blood 90 (4), 1490-1500. |
| Description |
This is a synthetic peptide designed for use in combination with anti-NAPA antibody (Catalog #: AVARP13049_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
