HTR3A Peptide (AAP30718)

Data Sheet
 
Sku AAP30718
Old sku AAPP01375
Price $99.00
Name HTR3A Peptide (AAP30718)
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Size 100 ug
Gene HTR3A
Alias symbols HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
Gene id 3359
Description of target HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Swissprot id P46098
Protein accession num NP_000860
Nucleotide accession num NM_000869
Protein size 478 amino acids
Molecular weight 55kDa
Application IHC, WB
Partner proteins CANX,HSPA5
Quality control The peptide is characterized by mass spectroscopy
Key reference Panicker,S., et al., (2004) J. Biol. Chem. 279 (27), 28149-28158
Description This is a synthetic peptide designed for use in combination with anti-HTR3A antibody (Catalog #: AVARP13046_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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