| Sku |
AAP30670 |
| Old sku |
AAPP01327 |
| Price |
$99.00 |
| Name |
CHRNG Peptide - N-terminal region (AAP30670) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
CHRNG |
| Alias symbols |
ACHRG |
| Gene id |
1146 |
| Description of target |
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[ |
| Swissprot id |
Q86U77 |
| Protein accession num |
NP_000734 |
| Nucleotide accession num |
NM_000743 |
| Protein size |
505 amino acids |
| Molecular weight |
57kDa |
| Application |
WB |
| Partner proteins |
Ubqln1; CHRNB4; |
| Subunit |
alpha-3 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Boorman,J.P., et al., (2003) J. Biol. Chem. 278 (45), 44033-44040 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CHRNA3 antibody (Catalog #: AVARP13014_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
