| Sku |
AAP30623 |
| Old sku |
AAPP01276 |
| Price |
$99.00 |
| Name |
TNFRSF10C Peptide - N-terminal region (AAP30623) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
TNFRSF10C |
| Alias symbols |
CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID, TRAIL-R3, DCR1-TNFR |
| Gene id |
8794 |
| Description of target |
TNFRSF10C is the receptor for the cytotoxic ligand TRAIL. TNFRSF10C lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. TNFRSF10C may protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
O14798 |
| Protein accession num |
NP_003832 |
| Nucleotide accession num |
NM_003841 |
| Protein size |
259 amino acids |
| Molecular weight |
25kDa |
| Application |
WB |
| Partner proteins |
TP53,APOA1,FAM101B,LRSAM1,RAP1A,SLC27A6,TNFSF10,ZHX1,APOA1,FAM101B,SLC27A6,ZHX1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Inagaki,S., (2007) Biosci. Biotechnol. Biochem. 71 (8), 2065-2068 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TNFRSF10C antibody (Catalog #: AVARP02039_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
