| Sku |
AAP30560 |
| Old sku |
AAPP01212 |
| Price |
$99.00 |
| Name |
BCL2A1 Peptide (AAP30560) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
BCL2A1 |
| Alias symbols |
GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5 |
| Gene id |
597 |
| Description of target |
BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. |
| Swissprot id |
Q16548 |
| Protein accession num |
NP_004040 |
| Nucleotide accession num |
NM_004049 |
| Protein size |
175 amino acids |
| Molecular weight |
20kDa |
| Application |
WB |
| Partner proteins |
BAD,BBC3,BID,BIK,HRK,PMAIP1,BAD,BAK1,BAX,BBC3,BCL2L11,BID,BIK,BOK,GRB2,HRK,PMAIP1,BAD,BAX,BCL2L11,BID,BIK,BMF,BOK,Bcl2l11,HRK,PMAIP1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Kunter,U., et al., (2005) Kidney Int. 68 (4), 1520-1532 |
| Description |
This is a synthetic peptide designed for use in combination with anti-BCL2A1 antibody (Catalog #: AVARP09047_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
