BCL2A1 Peptide (AAP30560)

Data Sheet
Sku AAP30560
Old sku AAPP01212
Price $99.00
Name BCL2A1 Peptide (AAP30560)
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Size 100 ug
Gene BCL2A1
Alias symbols GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5
Gene id 597
Description of target BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
Swissprot id Q16548
Protein accession num NP_004040
Nucleotide accession num NM_004049
Protein size 175 amino acids
Molecular weight 20kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Kunter,U., et al., (2005) Kidney Int. 68 (4), 1520-1532
Description This is a synthetic peptide designed for use in combination with anti-BCL2A1 antibody (Catalog #: AVARP09047_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days

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