TNFRSF10B Peptide (AAP30519)

Data Sheet
 
Sku AAP30519
Old sku AAPP01155
Price $99.00
Name TNFRSF10B Peptide (AAP30519)
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Size 100 ug
Gene TNFRSF10B
Alias symbols CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Gene id 8795
Description of target The protein is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Swissprot id O14763
Protein accession num NP_003833
Nucleotide accession num NM_003842
Protein size 440 amino acids
Molecular weight 42kDa
Application WB
Partner proteins PRKCD,RARA,TP53,CASP8,CFLAR,FADD,MADD,RIPK1,TNFRSF10A,TNFRSF10D,TNFSF10,TRADD,ARHGDIA,BID,CASP10,CASP8,CFLAR,EZR,FADD,FAS,FASLG,MAPK8,MSN,RHOA,RIPK1,TIMM50,TNFRSF1A,TNFSF10,TNFSF10,TRADD
Quality control The peptide is characterized by mass spectroscopy
Key reference Baritaki,S., (2008) J. Immunol. 180 (9), 6199-6210
Description This is a synthetic peptide designed for use in combination with anti-TNFRSF10B antibody (Catalog #: AVARP00032_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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