Sku |
AAP30519 |
Old sku |
AAPP01155 |
Price |
$99.00 |
Name |
TNFRSF10B Peptide (AAP30519) |
Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
Size |
100 ug |
Gene |
TNFRSF10B |
Alias symbols |
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 |
Gene id |
8795 |
Description of target |
The protein is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. |
Swissprot id |
O14763 |
Protein accession num |
NP_003833 |
Nucleotide accession num |
NM_003842 |
Protein size |
440 amino acids |
Molecular weight |
42kDa |
Application |
WB |
Partner proteins |
PRKCD,RARA,TP53,CASP8,CFLAR,FADD,MADD,RIPK1,TNFRSF10A,TNFRSF10D,TNFSF10,TRADD,ARHGDIA,BID,CASP10,CASP8,CFLAR,EZR,FADD,FAS,FASLG,MAPK8,MSN,RHOA,RIPK1,TIMM50,TNFRSF1A,TNFSF10,TNFSF10,TRADD |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Baritaki,S., (2008) J. Immunol. 180 (9), 6199-6210 |
Description |
This is a synthetic peptide designed for use in combination with anti-TNFRSF10B antibody (Catalog #: AVARP00032_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |