RIPK2 Peptide - middle region (AAP30513)

Data Sheet
 
Sku AAP30513
Old sku AAPP01149
Price $99.00
Name RIPK2 Peptide - middle region (AAP30513)
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Size 100 ug
Gene RIPK2
Alias symbols CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
Gene id 8767
Description of target RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id O43353
Protein accession num NP_003812
Nucleotide accession num NM_003821
Protein size 540 amino acids
Molecular weight 61kDa
Application IF, WB
Partner proteins NOD1,NOD2,BCL10,BIRC3,CARD16,CARD6,CASP1,CASP8,CD40,CFLAR,IKBKG,IRAK1,NGFR,NOD1,NOD2,SMAD4,SMURF1,TLR2,TLR4,TNFRSF1A,TRAF1,TRAF2,TRAF5,TRAF6,UBE2I,BIRC2,BIRC3,CARD6,CASP1,CD40,CFLAR,COP,IKBKG,KCTD12,NOD1,NOD2,PHB2,RPL38,RPS14,TNFRSF1A,TRAF1,TRAF2,TRAF5,TRAF6,UBC,UBE2I
Quality control The peptide is characterized by mass spectroscopy
Key reference Hasegawa,M., (2008) EMBO J. 27 (2), 373-383
Description This is a synthetic peptide designed for use in combination with anti-RIPK2 antibody (Catalog #: AVARP02047_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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