| Sku |
AAP30490 |
| Old sku |
AAPP01126 |
| Price |
$99.00 |
| Name |
NLRC4 Peptide (AAP30490) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NLRC4 |
| Alias symbols |
CLAN, IPAF, CLAN1, CLANA, CLANB, CLANC, CLAND, CARD12, CLR2.1 |
| Gene id |
58484 |
| Description of target |
In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1, NOD1, and NOD2. These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis. |
| Swissprot id |
Q9NPP4 |
| Protein accession num |
NP_067032 |
| Nucleotide accession num |
NM_021209 |
| Protein size |
1024 amino acids |
| Molecular weight |
116kDa |
| Application |
IHC, WB |
| Partner proteins |
BCL10,CASP1,NAIP,NLRC4,NLRP1,NLRP3,NLRP4,NOD1,NOD2,BCL10,CASP1,NLRP4,NOD2,PYCARD,BCL10,CASP1,NA,NAIP,NLRC4,NLRP1,NLRP3,NOD1,NOD2,PYCARD |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Clark,H.F., et al., (2003) Genome Res. 13 (10), 2265-2270 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CARD12 antibody (Catalog #: AVARP00019_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
