| Sku |
AAP30457 |
| Old sku |
AAPP01041 |
| Price |
$99.00 |
| Name |
NME1 Peptide - N-terminal region (AAP30457) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
NME1 |
| Alias symbols |
AWD, GAAD, NDPKA, NM23, NM23-H1, NB, NBS, NDKA, NDPK-A |
| Gene id |
4830 |
| Description of target |
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. |
| Swissprot id |
P22392 |
| Protein accession num |
NP_000260 |
| Nucleotide accession num |
NM_000269 |
| Protein size |
152 amino acids |
| Molecular weight |
17kDa |
| Application |
DB, IHC, WB |
| Partner proteins |
HHV4gp086,APEX1,AURKA,GORASP2,ITGB1,KSR1,MIF,NME1,NME3,NME4,POLR1C,PRUNE,RORA,RORB,RRAD,SET,TERF1,TIAM1,WDYHV1,AURKA,GORASP2,ITGB1,NME1,NME3,NME4,POLR1C,PRUNE,RAC1,RORA,RORB,RRAD,SET,TERF1,TIAM1,USP18,WDYHV1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Liu,S.J., (2008) Br. J. Cancer 98 (2), 363-369 |
| Description |
This is a synthetic peptide designed for use in combination with anti-NME1 antibody (Catalog #: AVARP00009_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
