| Sku |
AAP30360 |
| Old sku |
AAPP00818 |
| Price |
$99.00 |
| Name |
DOK2 Peptide (AAP30360) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
DOK2 |
| Alias symbols |
p56DOK, p56dok-2 |
| Gene id |
9046 |
| Description of target |
DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. |
| Swissprot id |
O60496 |
| Protein accession num |
NP_003965 |
| Nucleotide accession num |
NM_003974 |
| Protein size |
412 amino acids |
| Molecular weight |
45kDa |
| Application |
WB |
| Partner proteins |
INPP5D,RASA1,ABL1,EGFR,HCK,IL4R,INPP5D,KIAA1279,LCK,LYN,NCK1,RASA1,RET,SRC,TEK,ASF1B,CFLAR,DNAJB11,DOK1,EGFR,HSPA4L,INPP5D,KIAA1279,NCK1,PSMD10,RAB10,RASA1,RET,SHC1,SPOP,SSSCA1,TEK |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Boulay,I., et al., (2005) J. Immunol. 175 (7), 4483-4489 |
| Description |
This is a synthetic peptide designed for use in combination with anti-DOK2 antibody (Catalog #: AVARP09025_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
