CDC2 Peptide - middle region (AAP30329)

Data Sheet
 
Sku AAP30329
Old sku AAPP00710
Price $99.00
Name CDC2 Peptide - middle region (AAP30329)
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Size 100 ug
Gene CDK1
Alias symbols CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
Gene id 983
Description of target The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Swissprot id P06493
Protein accession num NP_001777
Nucleotide accession num NM_001786
Protein size 297 amino acids
Molecular weight 34kDa
Application WB
Partner proteins ABL1; SIRT1; CDC37; HUWE1; BTRC; UBC; HSP90AA1; HSPA4; HIST1H1A; GADD45A; CKS1B; USP16; Samhd1; UIMC1; SUMO2; CCNA2; STAU1; RNF2; CKS2; ZRANB2; CDKN1B; CDKN1A; CDK1; CCNB1; FBXO6; CCNB2; PKMYT1; SQSTM1; EGFR; PTMA; DCTN6; RGCC; BAG3; CDC25B; BCL2; TP53BP1
Quality control The peptide is characterized by mass spectroscopy
Key reference Boise,L.H., (2008) J. Virol. 82 (9), 4527-4532
Description This is a synthetic peptide designed for use in combination with anti-CDC2 antibody (Catalog #: AVARP01006_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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