Sku |
AAP30321 |
Old sku |
AAPP00702 |
Price |
$99.00 |
Name |
AKT2 Peptide - middle region (AAP30321) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
AKT2 |
Alias symbols |
PKBBETA, PRKBB, RAC-BETA, PKBB, HIHGHH |
Gene id |
208 |
Description of target |
AKT2 belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene encoding AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P31751 |
Protein accession num |
NP_001617 |
Nucleotide accession num |
NM_001626 |
Protein size |
481 amino acids |
Molecular weight |
56kDa |
Application |
WB |
Partner proteins |
APPL1,CHUK,TCL1A,AKT1,AKT1S1,AKT2,APPL1,CHUK,ESR1,FOXO4,FSHR,GSK3B,HSP90AA1,MTCP1,PDPK1,RAB3D,SH3RF1,SLC2A4,TCL1A,TCL1B,TRIB3,TSC2,XIAP,APPL1,CHUK,GSK3B,MTCP1,PRKDC,SH3RF1,TCL1A,TCL1B |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Tan,Y., (2008) Cancer Res. 68 (5), 1296-1302 |
Description |
This is a synthetic peptide designed for use in combination with anti-AKT2 antibody (Catalog #: ARP30321_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |