| Sku |
AAP30320 |
| Old sku |
AAPP00701 |
| Price |
$99.00 |
| Name |
FOXO4 Peptide - middle region (AAP30320) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
FOXO4 |
| Alias symbols |
AFX, AFX1, MGC120490, MLLT7 |
| Gene id |
4303 |
| Description of target |
FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias. |
| Swissprot id |
P98177 |
| Protein accession num |
NP_005929 |
| Nucleotide accession num |
NM_005938 |
| Protein size |
505 amino acids |
| Molecular weight |
54kDa |
| Application |
WB |
| Partner proteins |
AKT1,CCND1,CDKN1A,CTNNB1,FOXG1,SMAD3,SMAD4,AKT1,AKT2,CREBBP,CTNNB1,ESR1,FOXG1,SMAD3,SMAD4,XPO1,YWHAZ,CREBBP,ESR1,MDM2,PIN1,SMAD3,SMAD4,UBC,USP7,XPO1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Boura,E., (2007) J. Biol. Chem. 282 (11), 8265-8275 |
| Description |
This is a synthetic peptide designed for use in combination with anti-FOXO4 antibody (Catalog #: AVARP01018_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
