| Sku |
AAP30267 |
| Old sku |
AAPP00437 |
| Price |
$99.00 |
| Name |
CFLAR Peptide - C-terminal region (AAP30267) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
CFLAR |
| Alias symbols |
CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLIP, I-FLICE, MRIT, USURPIN, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, FLAME1 |
| Gene id |
8837 |
| Description of target |
CFLAR belongs to the peptidase C14A family. It is a apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. The protein acts as an inhibitor of TNFRSF6 mediated apoptosis. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. CFLAR lacks enzymatic (caspase) activity. |
| Swissprot id |
O15519 |
| Protein accession num |
NP_003870 |
| Nucleotide accession num |
NM_003879 |
| Protein size |
480 amino acids |
| Molecular weight |
55kDa |
| Application |
WB |
| Peptide sequence |
LRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT |
| Partner proteins |
CASP3,CASP8,FADD,BCL2L1,CASP3,CASP8,DAXX,FADD,BCL2L1,CASP10,CASP2,CASP3,CASP6,CASP7,CASP8,DAXX,DEDD,DEDD2,FADD,IKBKB,MAP2K4,MAP2K7,NFKB1,PSEN2,RAF1,RIPK1,RIPK2,TNFRSF10B,TRAF1,TRAF2,BCL2L1,CASP10,CASP3,CASP8,CFLAR,DEDD,DEDD2,DOK2,FADD,FAS,ITCH,MAP3K14,NOD1,NOL3,RAF1,RIPK1,RIPK2,SF3B3,TNFRSF10A,TNFRSF10B,TP53,TRAF1,TRAF2,TRAF3,UBC |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Geserick,P., (2008) Oncogene 27 (22), 3211-3220 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CFLAR antibody (Catalog #: AVARP02011_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
