MYC Peptide (AAP30255)

Data Sheet
 
Sku AAP30255
Old sku AAPP00425
Price $99.00
Name MYC Peptide (AAP30255)
Purchase info To purchase this peptide:
  • Copy peptide sku
  • Click on this link
  • Paste into field "Peptide Sku"
Size 100 ug
Gene MYC
Alias symbols MRTL, c-Myc, bHLHe39
Gene id 4609
Description of target MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Swissprot id P01106
Protein accession num NP_002458
Nucleotide accession num NM_002467
Protein size 439 amino acids
Molecular weight 49kDa
Application WB
Partner proteins E2F1,E2F4,E2F5,CHUK,ESR1,FUBP1,NCOA3,ORC2L,POLR2A,XRCC5,BRCA1,CDK4,CDKN1A,CDKN1A,CDKN1A,CDKN2A,CSNK2A1,DDB2,DNMT3A,FBXW7,FBXW7,KAT2A,MAPK3,MAX,MIR17HG,MLH1,MYCBP2,NCL,NFYB,NFYC,NMI,NPM1,PARP10,PMAIP1,PML,RIBIN,RRM2B,SP1,SP1,TAF1A,TAF1B,TAF1C,TBP,TRRAP,ACTL6A,BCL2,BIN1,BRCA1,CCNT1,CDC6,CDK1,CDKN2A,CEBPA,CEBPB,CREBBP,CSNK2A1,CSNK2A2,DNMT3A,ELF3,EP300,FBXW7,GSK3B,GTF2F1,GTF2I,HSP90AA1,KAT2A,KAT5,MAP2K1,MAPK3,MAPK7,MAPK8,MAX,MINA,MLH1,MXD1,MXI1,MYCBP,MYCBP2,NFYB,NFYC,NMI,PARP10,PFDN5,PML,PRDX1,RAF1,RAGE,RB1,RBL1,RELA,SKP2,SMAD2,SMAD3,SMARCB1,SNIP1,SP1,SPAG9,SUPT3H,TAF1B,TBP,TFAP2B,TIAM1,TP73,TRRAP,TUBA1A,TUBA1B,TUBA3C,TUBA4A,TUBA8,UBB,YY1,ZBTB17,ACTB,ACTL6A,ARHGEF2,BCL2,BRCA1,BRD7,CCNT1,CD6,CDC6,CDK9,CEBPA,CEBPB,DDX24,DNMT3A,EFTUD2,EP400,EXOC4,Eif4e,FANCI,FBXW7,GCN1L1,GEMIN4,GTF2B,GTF2F1,GTF2I,GTF3C3,HEATR1,HNRNPC,HSP90AA1,KAT2A,KAT2B,KAT5,KIAA1967,MAPK1,MAPK3,MAPK8,MAX,MCM7,MED12,MED14,METTL13,MKLN1,MLH1,MSH2,MSH6,MYBBP1A,MYCBP,MYCBP2,MYO1B,NFYB,NFYC,NMI,NUP205,NUP93,PDS5A,PFDN5,PIAS2,POLE,POLR2A,PRPF8,RAF1,RB1,RBL1,RELA,RUVBL1,RUVBL2,SAP130,SMAD2,SMAD3,SMARCA4,SMARCB1,SNRNP200,SP1,SUPT3H,TADA2A,TADA3,TAF10,TAF12,TAF5,TAF5L,TAF6L,TAF9,TBP,TFAP2A,TIAM1,TP73,TRRAP,UBB,YY1,ZBTB17
Quality control The peptide is characterized by mass spectroscopy
Key reference Frater,J.L., et al., (2006) Cancer Genet. Cytogenet. 166 (2), 139-145
Description This is a synthetic peptide designed for use in combination with anti-MYC antibody (Catalog #: AVARP04001_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
Protocol
Tips

See our General FAQ page.

Availability In Stock
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com