| Sku |
AAP30245 |
| Old sku |
AAPP00415 |
| Price |
$99.00 |
| Name |
CCND3 Peptide (AAP30245) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
CCND3 |
| Gene id |
896 |
| Description of target |
CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. |
| Swissprot id |
P30281 |
| Protein accession num |
NP_001751 |
| Nucleotide accession num |
NM_001760 |
| Protein size |
292 amino acids |
| Molecular weight |
33kDa |
| Application |
IHC, WB |
| Partner proteins |
AKAP8,AREG,ATF5,ATP5C1,CASP2,CDK11B,CDK14,CDK4,CDK6,CDKN1A,CDKN1B,CRABP2,DMTF1,DTNBP1,EFEMP2,EIF3K,MAF1,MAPK4,MCM10,NCOA2,NPDC1,PCNA,RARA,RBL2,RUNX1,VDR,AKAP8,ATP5C1,CASP2,CDK11B,CDK4,CDK6,CDKN1A,CDKN1B,CRABP2,DTNBP1,EFEMP2,EIF3K,MAF1,MCM10,NPDC1,PCNA,RARA,RB1,RBX1,TSC2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Pruneri,G., et al., (2004) Int. J. Cancer 112 (1), 71-77 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CCND3 antibody (Catalog #: AVARP03038_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
