Sku |
AAP30209 |
Old sku |
AAPP00366 |
Price |
$99.00 |
Name |
RGS10 Peptide (AAP30209) |
Purchase info |
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|
Size |
100 ug |
Gene |
RGS10 |
Gene id |
6001 |
Description of target |
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. |
Swissprot id |
Q96GN0 |
Protein accession num |
NP_001005339 |
Nucleotide accession num |
NM_001005339 |
Protein size |
181 amino acids |
Molecular weight |
21kDa |
Application |
FACS, WB |
Partner proteins |
CALM1,GNAI1,GNAI3,GNAO1,GNAZ,GNRHR,PRKACA,ACP6,EIF6,GNAI1,GNAI3,GNAZ,SAP18 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Chatterjee,T.K. et al., (2000) J. Biol. Chem. 275 (31), 24013-24021 |
Description |
This is a synthetic peptide designed for use in combination with anti-RGS10 antibody (Catalog #: AVARP09013_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |