RAD9A Peptide (AAP30207)

Data Sheet
 
Sku AAP30207
Old sku AAPP00364
Price $99.00
Name RAD9A Peptide (AAP30207)
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Size 100 ug
Gene RAD9A
Alias symbols RAD9
Gene id 5883
Description of target RAD9A is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM].
Swissprot id Q99638
Protein accession num NP_004575
Nucleotide accession num NM_004584
Protein size 391 amino acids
Molecular weight 42kDa
Application WB
Partner proteins DNAJC7,HUS1,HUS1,RPA1,RPA2,ABL1,AR,ATAD5,ATM,BCL2,BCL2L1,CHEK2,CLSPN,DNAJC7,HDAC1,HUS1,HUS1B,ITSN2,MLH1,PCNA,RAD17,RAD9B,TOPBP1,ABL1,AR,BCL2,BCL2L1,CLSPN,DNAJC7,FEN1,HDAC1,HUS1,HUS1B,NR3C1,RAD1,RAD17,RPA1,RPA2,TOPBP1
Quality control The peptide is characterized by mass spectroscopy
Key reference Moehren,U., (2008) Biochem. J. 411 (3), 679-686
Description This is a synthetic peptide designed for use in combination with anti-RAD9A antibody (Catalog #: AVARP03028_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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