| Sku |
AAP30194 |
| Old sku |
AAPP00351 |
| Price |
$99.00 |
| Name |
CDKN2B Peptide (AAP30194) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
CDKN2B |
| Alias symbols |
P15, MTS2, TP15, CDK4I, INK4B, p15INK4b |
| Gene id |
1030 |
| Description of target |
CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. |
| Swissprot id |
P42772 |
| Protein accession num |
NP_004927 |
| Nucleotide accession num |
NM_004936 |
| Protein size |
138 amino acids |
| Molecular weight |
15kDa |
| Application |
WB |
| Partner proteins |
PIAS2,ARPC3,CCDC90B,CDK4,CDK8,IKBKAP,KIAA1377,MAGEA11,ZBTB17,ARPC3,CCDC90B,CDK4,IKBKAP,KIAA1377,MAGEA11 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Scott,S.A., et al., (2004) Leuk. Res. 28 (12), 1293-1301 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CDKN2B antibody (Catalog #: AVARP03047_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
