| Sku |
AAP30171 |
| Old sku |
AAPP00328 |
| Price |
$99.00 |
| Name |
CCNH Peptide (AAP30171) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
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|
| Size |
100 ug |
| Gene |
CCNH |
| Alias symbols |
CAK, p34, p37 |
| Gene id |
902 |
| Description of target |
Cyclin H regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. It is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. |
| Swissprot id |
P51946 |
| Protein accession num |
NP_001230 |
| Nucleotide accession num |
NM_001239 |
| Protein size |
323 amino acids |
| Molecular weight |
38kDa |
| Application |
IHC, WB |
| Partner proteins |
AR,CDK2,CDK20,CDK7,CDK8,ERCC3,ESR1,FUBP1,GTF2E2,GTF2H1,MCM7,MTA1,PSMA1,SSSCA1,TP53,AR,CDK7,ERCC3,ESR1,FUBP1,GTF2H1,GTF2H2,MCM7,MNAT1,MTA1,POLR2A,PSMA1,RADIL,SSSCA1,SUPT5H,TP53 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Maekelae, T.P., et al., (1994) Nature 371:254-257. |
| Description |
This is a synthetic peptide designed for use in combination with anti-CCNH antibody (Catalog #: AVARP03026_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
