| Sku |
AAP30157 |
| Old sku |
AAPP00314 |
| Price |
$99.00 |
| Name |
CDK9 Peptide - N-terminal region (AAP30157) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
CDK9 |
| Alias symbols |
C-2k, CDC2L4, PITALRE, TAK, CTK1 |
| Gene id |
1025 |
| Description of target |
CDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. |
| Swissprot id |
P50750 |
| Protein accession num |
NP_001252 |
| Nucleotide accession num |
NM_001261 |
| Protein size |
372 amino acids |
| Molecular weight |
43kDa |
| Application |
IHC, WB |
| Partner proteins |
CCNT1,CCNT1,CCNT1,CCNT2,CCNT2,POLR2A,AFF4,AR,CCNK,CCNT1,CCNT2,CDC34,CDK5R1,CTDSPL,CUL1,DHX30,GRN,HEXIM1,HEXIM2,HSPA1A,HTATSF1,IL6ST,MED21,MYBL2,NBN,NFKB1,NR2E3,PIN1,POLR2A,RB1,RELA,SERPINH1,SKP2,STK36,SUPT5H,TP53,TRAF2,ZMYM6,AFF4,AR,ARID3B,BRD4,CCDC87,CCNK,CCNT1,CCNT2,CCT3,CCT4,CCT5,CCT8,CDC34,CDC73,CDK9,CKAP5,CSNK2B,CUL1,DDX5,DTYMK,EXOSC5,FKBP5,GRN,HEXIM1,HEXIM2,HNRNPA0,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPH1,HNRNPK,HNRNPR,HNRNPU,HSP90AB1,HSPA1A,HSPA2,HSPA5,HSPA6,HSPD1,IGF2BP1,IGF2BP2,IL6ST,ILF2,KIAA1967,KPNA2,LARP7,LOC440264,MATR3,MDFIC,MEPCE,MRPS27,MYBL2,MYC,NUFIP1,PCBP2,PGC,PMS1,POLR2A,RB1,RBM39,RELA,RFC4,RPS4X,RQCD1,RUVBL1,RUVBL2,SART3,SKP1,SKP2,SNRPD2P1,SUPT5H,SYNCRIP,TP53,TRIM28,TRIP12,TUBB2C,UBL4A,YBX1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Sabo,A., (2008) Mol. Cell. Biol. 28 (7), 2201-2212 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CDK9 antibody (Catalog #: AVARP03004_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
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