CDC25A Peptide - middle region (AAP30148)

Data Sheet
 
Sku AAP30148
Old sku AAPP00305
Price $99.00
Name CDC25A Peptide - middle region (AAP30148)
Purchase info To purchase this peptide:
  • Copy peptide sku
  • Click on this link
  • Paste into field "Peptide Sku"
Size 100 ug
Gene CDC25A
Alias symbols CDC25A2
Gene id 993
Description of target CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot id P30304
Protein accession num NP_963861
Nucleotide accession num NM_201567
Protein size 484 amino acids
Molecular weight 54kDa
Application WB
Partner proteins E2F1,E2F2,E2F3,E2F4,CHEK1,CHEK1,AR,BTRC,CCNA1,CCNB1,CCNE1,CDK1,CDK2,CDKN3,CHEK1,CHEK2,CUX1,EGFR,FBXW11,HRAS,MAP3K5,NAA10,PIM1,RAF1,ROCK1,SMAD3,UBB,YWHAB,YWHAE,YWHAZ,BTRC,CCNA1,CCNB1,CCNE1,CDK2,CHEK1,CHEK2,EGFR,MAP3K5,MAPK14,NAA10,PIM1,RAF1,ROCK1,UBC,YWHAB,YWHAB,YWHAE,YWHAE,YWHAZ
Quality control The peptide is characterized by mass spectroscopy
Key reference Ray,D. (2008) Cancer Res. 68 (5), 1251-1253
Description This is a synthetic peptide designed for use in combination with anti-CDC25A antibody (Catalog #: AVARP03040_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
Protocol
Tips

See our General FAQ page.

Availability In Stock
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com