CAV3 Peptide (AAP30146)

Data Sheet
 
Sku AAP30146
Old sku AAPP00303
Price $99.00
Name CAV3 Peptide (AAP30146)
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Size 100 ug
Gene CAV3
Alias symbols LQT9, VIP21, LGMD1C, VIP-21
Gene id 859
Description of target CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Swissprot id P56539
Protein accession num NP_001225
Nucleotide accession num NM_001234
Protein size 151 amino acids
Molecular weight 17kDa
Application IHC, WB
Partner proteins DAG1,DYSF,EGFR,GNAS,INSR,JPH2,NOS1,PFKM,SLC22A11,SLC8A1,DAG1,DYSF,EGFR,JPH2,PDGFRA,PDGFRB,PFKM,SLC8A1
Quality control The peptide is characterized by mass spectroscopy
Key reference Alias,L., et al., (2004) Neuromuscul. Disord. 14 (5), 321-324
Description This is a synthetic peptide designed for use in combination with anti-CAV3 antibody (Catalog #: AVARP09021_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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