| Sku |
AAP30145 |
| Old sku |
AAPP00302 |
| Price |
$99.00 |
| Name |
CAV2 Peptide - N-terminal region (AAP30145) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
CAV2 |
| Alias symbols |
CAV, MGC12294 |
| Gene id |
858 |
| Description of target |
CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript. |
| Swissprot id |
P51636 |
| Protein accession num |
NP_001224 |
| Nucleotide accession num |
NM_001233 |
| Protein size |
162 amino acids |
| Molecular weight |
18kDa |
| Application |
IHC, WB |
| Partner proteins |
CAV1,DRD1,EGFR,FLOT2,GOLGB1,MALL,NCK1,RASA1,SRC,CAV1,NCK1,PLD2,RASA1,SRC |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Sowa,G., (2008) Biochemistry 47 (1), 101-111 |
| Description |
This is a synthetic peptide designed for use in combination with anti-CAV2 antibody (Catalog #: AVARP09020_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
