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Gene ID: 3381 | IBSP Antibody Resource


IBSP Antibody Resource
Gene Full Name: 
integrin-binding sialoprotein
Uniprot: 
P21815
Protein Name: 
bone sialoprotein 2
Nucleotide: 
NM_004967
Alias: 
BSP;BNSP;SP-II;BSP-II;
Ensembl: 
Location: 
4q21.1
HPRD: 
00951
NCBI Gene: 
3381
MIM: 
147563

Summary: 
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
Function: 
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
Subcellular location: 
Secreted.
PTM: 
Glycoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP36681_T100 IBSP antibody - N-terminal region (ARP36681_T100) Polyclonal Human WB 100ug $229 Details
Polyclonal Antibody OASA07480 RABBIT ANTI HUMAN BONE SIALOPROTEIN II Antibody ELISA 1ml $350 Details
Polyclonal Antibody ARP36680_P050 IBSP Antibody (ARP36680_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB10414 IBSP antibody - N - terminal region (OAAB10414) Human WB 400ul $289 Details

Show all IBSP antibodies


Product Images
IBSP antibody - N-terminal region (ARP36681_T100) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

IBSP antibody - N - terminal region (OAAB10414) in CEM cells using Western Blot

Sample Type: CEM


IBSP Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP36680 Bovine IBSP antibody; Bos taurus IBSP antibody Q28862 93.0%
ARP36680 Cat IBSP antibody; Felis catus IBSP antibody M3WAT3 100.0%
ARP43960 Cat IBSP antibody; Felis catus IBSP antibody M3WAT3 80.0%
ARP36680 Chimpanzee IBSP antibody; Pan troglodytes IBSP antibody H2QPV2 100.0%
ARP36681 Chimpanzee IBSP antibody; Pan troglodytes IBSP antibody H2QPV2 100.0%
ARP40550 Chimpanzee IBSP antibody; Pan troglodytes IBSP antibody H2QPV2 91.0%
ARP36680 Chinese softshell turtle IBSP antibody; Pelodiscus sinensis IBSP antibody K7FG74 85.0%
ARP36680 Cuvier's dwarf caiman IBSP antibody; Paleosuchus palpebrosus IBSP antibody B3SXQ5 79.0%
ARP36680 Dog IBSP antibody; Canis familiaris IBSP antibody E2RPB1 100.0%
ARP36681 Dog IBSP antibody; Canis familiaris IBSP antibody E2RPB1 79.0%
ARP36680 European domestic ferret IBSP antibody; Mustela putorius furo IBSP antibody M3XT14 100.0%
ARP36680 Giant panda IBSP antibody; Ailuropoda melanoleuca IBSP antibody D2GX57 100.0%
ARP36680 Gray short-tailed opossum IBSP antibody; Monodelphis domestica IBSP antibody F7G8V1 100.0%
ARP36680 Green anole IBSP antibody; Anolis carolinensis IBSP antibody G1KML5 79.0%
ARP36680 Horse IBSP antibody; Equus caballus IBSP antibody F6YPI2 100.0%
ARP36680 Human IBSP antibody; Homo sapiens IBSP antibody P21815 100.0%
ARP36681 Human IBSP antibody; Homo sapiens IBSP antibody P21815 100.0%
ARP40550 Human IBSP antibody; Homo sapiens IBSP antibody P21815 91.0%
ARP36680 Mouse IBSP antibody; Mus musculus IBSP antibody Q3TRM5 92.0%
ARP36680 Mouse IBSP antibody; Mus musculus IBSP antibody Q61711 92.0%
ARP36680 Pig IBSP antibody; Sus scrofa IBSP antibody K7GP14 93.0%
ARP36680 Pig IBSP antibody; Sus scrofa IBSP antibody P31936 93.0%
ARP36680 Rabbit IBSP antibody; Oryctolagus cuniculus IBSP antibody G1SEM1 92.0%
ARP36680 Rat IBSP antibody; Rattus norvegicus IBSP antibody P13839 92.0%
ARP36680 Rat IBSP antibody; Rattus norvegicus IBSP antibody Q3HLN4 92.0%
ARP36680 Rat IBSP antibody; Rattus norvegicus IBSP antibody A0JPM6 92.0%
ARP36680 Rhesus macaque IBSP antibody; Macaca mulatta IBSP antibody F6TZH2 100.0%
ARP40550 Rhesus macaque IBSP antibody; Macaca mulatta IBSP antibody F6TZH2 91.0%
ARP36681 Rhesus macaque IBSP antibody; Macaca mulatta IBSP antibody F6TZH2 79.0%
ARP36680 Small-eared galago IBSP antibody; Otolemur garnettii IBSP antibody H0X499 93.0%
ARP36680 Sumatran orangutan IBSP antibody; Pongo abelii IBSP antibody H2PDV2 100.0%
ARP40550 Sumatran orangutan IBSP antibody; Pongo abelii IBSP antibody H2PDV2 91.0%
ARP36681 Sumatran orangutan IBSP antibody; Pongo abelii IBSP antibody H2PDV2 86.0%
ARP36680 Tasmanian devil IBSP antibody; Sarcophilus harrisii IBSP antibody G3VPY7 92.0%
ARP36680 Thirteen-lined ground squirrel IBSP antibody; Spermophilus tridecemlineatus IBSP antibody I3LYK5 92.0%
ARP36680 White-tufted-ear marmoset IBSP antibody; Callithrix jacchus IBSP antibody F7I699 93.0%
ARP36680 White-tufted-ear marmoset IBSP antibody; Callithrix jacchus IBSP antibody F7I6C9 93.0%
ARP40550 White-tufted-ear marmoset IBSP antibody; Callithrix jacchus IBSP antibody F7I699 91.0%
ARP40550 White-tufted-ear marmoset IBSP antibody; Callithrix jacchus IBSP antibody F7I6C9 91.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207370_at721_B_lymphoblasts17.10021.520Details
BioGPS Gene Atlas207370_atAdipocyte21.25021.520Details
BioGPS Gene Atlas207370_atAdrenalCortex29.90021.520Details
BioGPS Gene Atlas207370_atAdrenalgland26.25021.520Details
BioGPS Gene Atlas207370_atAmygdala16.50021.520Details
BioGPS Gene Atlas207370_atAppendix27.40021.520Details
BioGPS Gene Atlas207370_atAtrioventricularNode26.45021.520Details
BioGPS Gene Atlas207370_atBDCA4+_DentriticCells15.10021.520Details
BioGPS Gene Atlas207370_atBonemarrow21.75021.520Details
BioGPS Gene Atlas207370_atBronchialEpithelialCells14.20021.520Details
BioGPS Gene Atlas207370_atCD105+_Endothelial23.80021.520Details
BioGPS Gene Atlas207370_atCD14+_Monocytes16.90021.520Details
BioGPS Gene Atlas207370_atCD19+_BCells(neg._sel.)17.65021.520Details
BioGPS Gene Atlas207370_atCD33+_Myeloid25.80021.520Details
BioGPS Gene Atlas207370_atCD34+25.40021.520Details
BioGPS Gene Atlas207370_atCD4+_Tcells18.65021.520Details
BioGPS Gene Atlas207370_atCD56+_NKCells17.95021.520Details
BioGPS Gene Atlas207370_atCD71+_EarlyErythroid16.30021.520Details
BioGPS Gene Atlas207370_atCD8+_Tcells15.45021.520Details
BioGPS Gene Atlas207370_atCardiacMyocytes76.10021.520Details
BioGPS Gene Atlas207370_atCaudatenucleus15.65021.520Details
BioGPS Gene Atlas207370_atCerebellum18.00021.520Details
BioGPS Gene Atlas207370_atCerebellumPeduncles23.55021.520Details
BioGPS Gene Atlas207370_atCiliaryGanglion19.35021.520Details
BioGPS Gene Atlas207370_atCingulateCortex26.65021.520Details
BioGPS Gene Atlas207370_atColorectaladenocarcinoma18.60021.520Details
BioGPS Gene Atlas207370_atDorsalRootGanglion19.60021.520Details
BioGPS Gene Atlas207370_atFetalThyroid17.45021.520Details
BioGPS Gene Atlas207370_atFetalbrain16.55021.520Details
BioGPS Gene Atlas207370_atFetalliver18.50021.520Details
BioGPS Gene Atlas207370_atFetallung11.50021.520Details
BioGPS Gene Atlas207370_atGlobusPallidus24.80021.520Details
BioGPS Gene Atlas207370_atHeart36.95021.520Details
BioGPS Gene Atlas207370_atHypothalamus17.55021.520Details
BioGPS Gene Atlas207370_atKidney18.55021.520Details
BioGPS Gene Atlas207370_atLeukemia_chronicMyelogenousK-56215.15021.520Details
BioGPS Gene Atlas207370_atLeukemia_promyelocytic-HL-6014.30021.520Details
BioGPS Gene Atlas207370_atLeukemialymphoblastic(MOLT-4)12.50021.520Details
BioGPS Gene Atlas207370_atLiver25.65021.520Details
BioGPS Gene Atlas207370_atLung17.05021.520Details
BioGPS Gene Atlas207370_atLymphnode13.90021.520Details
BioGPS Gene Atlas207370_atLymphoma_burkitts(Daudi)24.25021.520Details
BioGPS Gene Atlas207370_atLymphoma_burkitts(Raji)28.60021.520Details
BioGPS Gene Atlas207370_atMedullaOblongata19.15021.520Details
BioGPS Gene Atlas207370_atOccipitalLobe19.10021.520Details
BioGPS Gene Atlas207370_atOlfactoryBulb13.05021.520Details
BioGPS Gene Atlas207370_atOvary15.85021.520Details
BioGPS Gene Atlas207370_atPancreas13.85021.520Details
BioGPS Gene Atlas207370_atPancreaticIslet17.60021.520Details
BioGPS Gene Atlas207370_atParietalLobe20.85021.520Details
BioGPS Gene Atlas207370_atPituitary25.95021.520Details
BioGPS Gene Atlas207370_atPlacenta15.10021.520Details
BioGPS Gene Atlas207370_atPons23.20021.520Details
BioGPS Gene Atlas207370_atPrefrontalCortex20.25021.520Details
BioGPS Gene Atlas207370_atProstate18.75021.520Details
BioGPS Gene Atlas207370_atSalivarygland15.70021.520Details
BioGPS Gene Atlas207370_atSkeletalMuscle42.15021.520Details
BioGPS Gene Atlas207370_atSkin24.85021.520Details
BioGPS Gene Atlas207370_atSmoothMuscle18.25021.520Details
BioGPS Gene Atlas207370_atSpinalcord24.35021.520Details
BioGPS Gene Atlas207370_atSubthalamicNucleus25.80021.520Details
BioGPS Gene Atlas207370_atSuperiorCervicalGanglion31.50021.520Details
BioGPS Gene Atlas207370_atTemporalLobe30.00021.520Details
BioGPS Gene Atlas207370_atTestis15.35021.520Details
BioGPS Gene Atlas207370_atTestisGermCell13.10021.520Details
BioGPS Gene Atlas207370_atTestisIntersitial15.75021.520Details
BioGPS Gene Atlas207370_atTestisLeydigCell23.00021.520Details
BioGPS Gene Atlas207370_atTestisSeminiferousTubule33.45021.520Details
BioGPS Gene Atlas207370_atThalamus18.85021.520Details
BioGPS Gene Atlas207370_atThymus12.35021.520Details
BioGPS Gene Atlas207370_atThyroid20.10021.520Details
BioGPS Gene Atlas207370_atTongue31.55021.520Details
BioGPS Gene Atlas207370_atTonsil18.70021.520Details
BioGPS Gene Atlas207370_atTrachea25.95021.520Details
BioGPS Gene Atlas207370_atTrigeminalGanglion47.90021.520Details
BioGPS Gene Atlas207370_atUterus12.35021.520Details
BioGPS Gene Atlas207370_atUterusCorpus17.00021.520Details
BioGPS Gene Atlas207370_atWholeBlood14.45021.520Details
BioGPS Gene Atlas207370_atWholebrain12.70021.520Details
BioGPS Gene Atlas207370_atcolon19.55021.520Details
BioGPS Gene Atlas207370_atpineal_day22.20021.520Details
BioGPS Gene Atlas207370_atpineal_night23.98021.520Details
BioGPS Gene Atlas207370_atretina25.32521.520Details
BioGPS Gene Atlas207370_atsmall_intestine15.55021.520Details
BioGPS NCI60207370_at78612.27114.270Details
BioGPS NCI60207370_atA1729.10014.270Details
BioGPS NCI60207370_atA20412.73314.270Details
BioGPS NCI60207370_atA36119.84414.270Details
BioGPS NCI60207370_atA49814.16714.270Details
BioGPS NCI60207370_atA54912.50814.270Details
BioGPS NCI60207370_atACC315.84714.270Details
BioGPS NCI60207370_atACHN10.56214.270Details
BioGPS NCI60207370_atALVA3119.46514.270Details
BioGPS NCI60207370_atCAKI118.26314.270Details
BioGPS NCI60207370_atCCRT CEM57.23214.270Details
BioGPS NCI60207370_atCOLO20513.53014.270Details
BioGPS NCI60207370_atDLD110.98814.270Details
BioGPS NCI60207370_atDU14516.20114.270Details
BioGPS NCI60207370_atEKVX10.48914.270Details
BioGPS NCI60207370_atGM13311.92414.270Details
BioGPS NCI60207370_atGM160012.12114.270Details
BioGPS NCI60207370_atGM23137.77414.270Details
BioGPS NCI60207370_atGM234511.92414.270Details
BioGPS NCI60207370_atGM249312.34514.270Details
BioGPS NCI60207370_atGM9713.67714.270Details
BioGPS NCI60207370_atHCC29987.60414.270Details
BioGPS NCI60207370_atHCT11612.85914.270Details
BioGPS NCI60207370_atHCT1510.29314.270Details
BioGPS NCI60207370_atHEK 293 T-rex25.95514.270Details
BioGPS NCI60207370_atHEK 293T11.68414.270Details
BioGPS NCI60207370_atHEK29311.48314.270Details
BioGPS NCI60207370_atHELA9.16014.270Details
BioGPS NCI60207370_atHEPG213.24914.270Details
BioGPS NCI60207370_atHL6019.69014.270Details
BioGPS NCI60207370_atHOP6212.27714.270Details
BioGPS NCI60207370_atHOP9210.61214.270Details
BioGPS NCI60207370_atHS578T11.65314.270Details
BioGPS NCI60207370_atHSG11.43114.270Details
BioGPS NCI60207370_atHT108011.74114.270Details
BioGPS NCI60207370_atHT2920.66714.270Details
BioGPS NCI60207370_atIGROV111.60514.270Details
BioGPS NCI60207370_atIOSE8011.28614.270Details
BioGPS NCI60207370_atJURKAT14.20814.270Details
BioGPS NCI60207370_atK56230.95514.270Details
BioGPS NCI60207370_atKM1217.15614.270Details
BioGPS NCI60207370_atLN189.81414.270Details
BioGPS NCI60207370_atLNCAP12.27314.270Details
BioGPS NCI60207370_atLOX IMVI14.02114.270Details
BioGPS NCI60207370_atM149.60814.270Details
BioGPS NCI60207370_atMALME 3M39.40214.270Details
BioGPS NCI60207370_atMCF77.10914.270Details
BioGPS NCI60207370_atMD MB23113.96114.270Details
BioGPS NCI60207370_atMDA MB43519.35614.270Details
BioGPS NCI60207370_atMOLT417.18614.270Details
BioGPS NCI60207370_atNCI 46013.91014.270Details
BioGPS NCI60207370_atNCI H22614.63014.270Details
BioGPS NCI60207370_atNCI H2321.53614.270Details
BioGPS NCI60207370_atNCI H322M14.41614.270Details
BioGPS NCI60207370_atNCVADR RES8.48814.270Details
BioGPS NCI60207370_atOVCAR313.47914.270Details
BioGPS NCI60207370_atOVCAR411.82114.270Details
BioGPS NCI60207370_atOVCAR511.65714.270Details
BioGPS NCI60207370_atOVCAR89.22714.270Details
BioGPS NCI60207370_atPANC115.31914.270Details
BioGPS NCI60207370_atRL713.95114.270Details
BioGPS NCI60207370_atRPMI 822614.38914.270Details
BioGPS NCI60207370_atRS1184617.41214.270Details
BioGPS NCI60207370_atRXF39311.84714.270Details
BioGPS NCI60207370_atSAOS228.46514.270Details
BioGPS NCI60207370_atSF26812.22514.270Details
BioGPS NCI60207370_atSF29511.05814.270Details
BioGPS NCI60207370_atSF53912.88114.270Details
BioGPS NCI60207370_atSHSYSY+RA11.21814.270Details
BioGPS NCI60207370_atSHSYSY-RA11.70514.270Details
BioGPS NCI60207370_atSKMEL211.75714.270Details
BioGPS NCI60207370_atSKMEL2812.22114.270Details
BioGPS NCI60207370_atSKMEL511.08414.270Details
BioGPS NCI60207370_atSKOV319.37814.270Details
BioGPS NCI60207370_atSN12C11.24714.270Details
BioGPS NCI60207370_atSNB1910.43014.270Details
BioGPS NCI60207370_atSNB7514.25414.270Details
BioGPS NCI60207370_atSR13.14014.270Details
BioGPS NCI60207370_atSW62015.92114.270Details
BioGPS NCI60207370_atT2413.13014.270Details
BioGPS NCI60207370_atT3M418.70514.270Details
BioGPS NCI60207370_atTK1030.28814.270Details
BioGPS NCI60207370_atU11810.77714.270Details
BioGPS NCI60207370_atU1388.56814.270Details
BioGPS NCI60207370_atU20S10.99214.270Details
BioGPS NCI60207370_atU25111.69314.270Details
BioGPS NCI60207370_atU8710.46014.270Details
BioGPS NCI60207370_atUACC25712.41514.270Details
BioGPS NCI60207370_atUACC6212.49014.270Details
BioGPS NCI60207370_atUO3110.07714.270Details
BioGPS NCI60207370_atZR75_113.05814.270Details
BioGPS NCI60207370_atastrocytes11.34814.270Details
BioGPS NCI60207370_athuh-714.07914.270Details