Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 9420 | CYP7B1 Antibody Resource


CYP7B1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 7, subfamily B, polypeptide 1
Uniprot: 
O75881
Protein Name: 
25-hydroxycholesterol 7-alpha-hydroxylase
Nucleotide: 
NM_004820
Alias: 
CP7B;CBAS3;SPG5A;
Ensembl: 
ENSG00000172817
Location: 
8q21.3
HPRD: 
04753
NCBI Gene: 
9420
MIM: 
603711

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008]
Function: 
Subcellular location: 
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
PTM: 
Disease: 
Spastic paraplegia 5A, autosomal recessive (SPG5A) [MIM:270800]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Note: The disease is caused by mutations affecting the gene represented in this entry. Congenital bile acid synthesis defect 3 (CBAS3) [MIM:613812]: A disorder resulting in severe cholestasis, cirrhosis and liver synthetic failure. Hepatic microsomal oxysterol 7-alpha-hydroxylase activity is undetectable. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP60826_P050 CYP7B1 antibody - C-terminal region (ARP60826_P050) Polyclonal Dog, Human, Pig, Rabbit WB 50ug $289 Details
Polyclonal Antibody OAEB00863 CYP7B1 Antibody (OAEB00863) Dog, Guinea pig, Pig, Rabbit IHC 0.1mg $289 Details
Polyclonal Antibody OAAB05382 CYP7B1 antibody - center region (OAAB05382) Human WB, IHC, FC, ELISA 400ul $289 Details
Polyclonal Antibody ARP60827_P050 CYP7B1 Antibody (ARP60827_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody OAAF02967 CYP7B1 Antibody (OAAF02967) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all CYP7B1 antibodies


Product Images
CYP7B1 antibody - C-terminal region (ARP60826_P050) in Human 721_B cells using Western Blot

Sample Type: Human 721_B

CYP7B1 antibody - center region (OAAB05382) in Hela cells using Western Blot

Sample Type: Hela

CYP7B1 antibody - center region (OAAB05382) in Hela cells using Flow Cytometry

Sample Type: Hela

CYP7B1 antibody - center region (OAAB05382) in human brain cells using Immunohistochemistry

Sample Type: human brain

CYP7B1 Antibody (OAAF02967) in LOVO cells using Western Blot

Sample Type: LOVO

CYP7B1 Antibody (OAEB00863) in Human Breast cells using Immunohistochemistry

Sample Type: Human Breast


CYP7B1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60826 Bovine CYP7B1 antibody; Bos taurus CYP7B1 antibody E1BAX6 85.0%
ARP60826 Cat CYP7B1 antibody; Felis catus CYP7B1 antibody M3WCV9 100.0%
ARP33250 Cat CYP7B1 antibody; Felis catus CYP7B1 antibody M3WCV9 82.0%
ARP60826 Chimpanzee CYP7B1 antibody; Pan troglodytes CYP7B1 antibody H2R9T2 100.0%
ARP60827 Chimpanzee CYP7B1 antibody; Pan troglodytes CYP7B1 antibody H2R9T2 100.0%
ARP60826 Chimpanzee CYP7B1 antibody; Pan troglodytes CYP7B1 antibody K7CPE1 100.0%
ARP60827 Chimpanzee CYP7B1 antibody; Pan troglodytes CYP7B1 antibody K7CPE1 100.0%
ARP60826 Chinese softshell turtle CYP7B1 antibody; Pelodiscus sinensis CYP7B1 antibody K7GCR9 86.0%
ARP60826 Chinese softshell turtle CYP7B1 antibody; Pelodiscus sinensis CYP7B1 antibody K7GCS7 86.0%
ARP60826 Dog CYP7B1 antibody; Canis familiaris CYP7B1 antibody F1PTV4 93.0%
ARP60826 European domestic ferret CYP7B1 antibody; Mustela putorius furo CYP7B1 antibody M3YEN2 93.0%
ARP60826 Giant panda CYP7B1 antibody; Ailuropoda melanoleuca CYP7B1 antibody D2H414 100.0%
ARP60826 Horse CYP7B1 antibody; Equus caballus CYP7B1 antibody F7BTH5 93.0%
ARP33250 Horse CYP7B1 antibody; Equus caballus CYP7B1 antibody F7BTH5 82.0%
ARP60826 Human CYP7B1 antibody; Homo sapiens CYP7B1 antibody O75881 100.0%
ARP60827 Human CYP7B1 antibody; Homo sapiens CYP7B1 antibody O75881 100.0%
ARP60826 Human CYP7B1 antibody; Homo sapiens CYP7B1 antibody Q05C57 100.0%
ARP60827 Human CYP7B1 antibody; Homo sapiens CYP7B1 antibody Q05C57 100.0%
ARP60826 Pig CYP7B1 antibody; Sus scrofa CYP7B1 antibody I3LRY8 86.0%
ARP60826 Rabbit CYP7B1 antibody; Oryctolagus cuniculus CYP7B1 antibody G1SDA9 85.0%
ARP60826 Rhesus macaque CYP7B1 antibody; Macaca mulatta CYP7B1 antibody F7GUB0 100.0%
ARP60827 Rhesus macaque CYP7B1 antibody; Macaca mulatta CYP7B1 antibody F7GUB0 100.0%
ARP60826 Rhesus macaque CYP7B1 antibody; Macaca mulatta CYP7B1 antibody H9G217 100.0%
ARP60827 Rhesus macaque CYP7B1 antibody; Macaca mulatta CYP7B1 antibody H9G217 100.0%
ARP60826 Small-eared galago CYP7B1 antibody; Otolemur garnettii CYP7B1 antibody H0XF28 93.0%
ARP60826 Sumatran orangutan CYP7B1 antibody; Pongo abelii CYP7B1 antibody H2PQF4 100.0%
ARP60827 Sumatran orangutan CYP7B1 antibody; Pongo abelii CYP7B1 antibody H2PQF4 100.0%
ARP60826 Thirteen-lined ground squirrel CYP7B1 antibody; Spermophilus tridecemlineatus CYP7B1 antibody I3MGD0 93.0%
ARP60826 White-tufted-ear marmoset CYP7B1 antibody; Callithrix jacchus CYP7B1 antibody F6UDE6 100.0%
ARP60827 White-tufted-ear marmoset CYP7B1 antibody; Callithrix jacchus CYP7B1 antibody F6UDE6 100.0%
ARP60826 White-tufted-ear marmoset CYP7B1 antibody; Callithrix jacchus CYP7B1 antibody F7CHT7 100.0%
ARP60827 White-tufted-ear marmoset CYP7B1 antibody; Callithrix jacchus CYP7B1 antibody F7CHT7 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207386_at721_B_lymphoblasts8.8006.310Details
BioGPS Gene Atlas207386_atAdipocyte5.9506.310Details
BioGPS Gene Atlas207386_atAdrenalCortex7.0006.310Details
BioGPS Gene Atlas207386_atAdrenalgland5.3506.310Details
BioGPS Gene Atlas207386_atAmygdala5.9506.310Details
BioGPS Gene Atlas207386_atAppendix9.6506.310Details
BioGPS Gene Atlas207386_atAtrioventricularNode5.8506.310Details
BioGPS Gene Atlas207386_atBDCA4+_DentriticCells5.8006.310Details
BioGPS Gene Atlas207386_atBonemarrow6.1506.310Details
BioGPS Gene Atlas207386_atBronchialEpithelialCells5.8006.310Details
BioGPS Gene Atlas207386_atCD105+_Endothelial5.8506.310Details
BioGPS Gene Atlas207386_atCD14+_Monocytes6.2506.310Details
BioGPS Gene Atlas207386_atCD19+_BCells(neg._sel.)6.0506.310Details
BioGPS Gene Atlas207386_atCD33+_Myeloid7.7506.310Details
BioGPS Gene Atlas207386_atCD34+7.2006.310Details
BioGPS Gene Atlas207386_atCD4+_Tcells6.1006.310Details
BioGPS Gene Atlas207386_atCD56+_NKCells6.7506.310Details
BioGPS Gene Atlas207386_atCD71+_EarlyErythroid5.6006.310Details
BioGPS Gene Atlas207386_atCD8+_Tcells5.3006.310Details
BioGPS Gene Atlas207386_atCardiacMyocytes8.3006.310Details
BioGPS Gene Atlas207386_atCaudatenucleus5.2506.310Details
BioGPS Gene Atlas207386_atCerebellum4.8006.310Details
BioGPS Gene Atlas207386_atCerebellumPeduncles7.6006.310Details
BioGPS Gene Atlas207386_atCiliaryGanglion11.3506.310Details
BioGPS Gene Atlas207386_atCingulateCortex6.4006.310Details
BioGPS Gene Atlas207386_atColorectaladenocarcinoma5.9006.310Details
BioGPS Gene Atlas207386_atDorsalRootGanglion5.1006.310Details
BioGPS Gene Atlas207386_atFetalThyroid5.8006.310Details
BioGPS Gene Atlas207386_atFetalbrain5.5506.310Details
BioGPS Gene Atlas207386_atFetalliver5.1006.310Details
BioGPS Gene Atlas207386_atFetallung4.6506.310Details
BioGPS Gene Atlas207386_atGlobusPallidus4.6506.310Details
BioGPS Gene Atlas207386_atHeart8.5006.310Details
BioGPS Gene Atlas207386_atHypothalamus6.0506.310Details
BioGPS Gene Atlas207386_atKidney5.4006.310Details
BioGPS Gene Atlas207386_atLeukemia_chronicMyelogenousK-5625.3006.310Details
BioGPS Gene Atlas207386_atLeukemia_promyelocytic-HL-605.1506.310Details
BioGPS Gene Atlas207386_atLeukemialymphoblastic(MOLT-4)4.6006.310Details
BioGPS Gene Atlas207386_atLiver8.6006.310Details
BioGPS Gene Atlas207386_atLung6.3006.310Details
BioGPS Gene Atlas207386_atLymphnode4.9006.310Details
BioGPS Gene Atlas207386_atLymphoma_burkitts(Daudi)7.6006.310Details
BioGPS Gene Atlas207386_atLymphoma_burkitts(Raji)8.9506.310Details
BioGPS Gene Atlas207386_atMedullaOblongata5.3506.310Details
BioGPS Gene Atlas207386_atOccipitalLobe5.3006.310Details
BioGPS Gene Atlas207386_atOlfactoryBulb4.6006.310Details
BioGPS Gene Atlas207386_atOvary5.7506.310Details
BioGPS Gene Atlas207386_atPancreas4.9506.310Details
BioGPS Gene Atlas207386_atPancreaticIslet6.2506.310Details
BioGPS Gene Atlas207386_atParietalLobe6.5506.310Details
BioGPS Gene Atlas207386_atPituitary6.7006.310Details
BioGPS Gene Atlas207386_atPlacenta5.7506.310Details
BioGPS Gene Atlas207386_atPons6.0506.310Details
BioGPS Gene Atlas207386_atPrefrontalCortex6.9506.310Details
BioGPS Gene Atlas207386_atProstate6.8506.310Details
BioGPS Gene Atlas207386_atSalivarygland4.8506.310Details
BioGPS Gene Atlas207386_atSkeletalMuscle8.0506.310Details
BioGPS Gene Atlas207386_atSkin6.2006.310Details
BioGPS Gene Atlas207386_atSmoothMuscle6.5506.310Details
BioGPS Gene Atlas207386_atSpinalcord6.2506.310Details
BioGPS Gene Atlas207386_atSubthalamicNucleus5.9506.310Details
BioGPS Gene Atlas207386_atSuperiorCervicalGanglion10.1506.310Details
BioGPS Gene Atlas207386_atTemporalLobe5.5006.310Details
BioGPS Gene Atlas207386_atTestis5.0506.310Details
BioGPS Gene Atlas207386_atTestisGermCell4.7506.310Details
BioGPS Gene Atlas207386_atTestisIntersitial5.1506.310Details
BioGPS Gene Atlas207386_atTestisLeydigCell6.2506.310Details
BioGPS Gene Atlas207386_atTestisSeminiferousTubule5.0506.310Details
BioGPS Gene Atlas207386_atThalamus6.0006.310Details
BioGPS Gene Atlas207386_atThymus4.4006.310Details
BioGPS Gene Atlas207386_atThyroid7.0506.310Details
BioGPS Gene Atlas207386_atTongue6.7506.310Details
BioGPS Gene Atlas207386_atTonsil5.7006.310Details
BioGPS Gene Atlas207386_atTrachea4.9006.310Details
BioGPS Gene Atlas207386_atTrigeminalGanglion9.4506.310Details
BioGPS Gene Atlas207386_atUterus4.5506.310Details
BioGPS Gene Atlas207386_atUterusCorpus6.1006.310Details
BioGPS Gene Atlas207386_atWholeBlood6.4006.310Details
BioGPS Gene Atlas207386_atWholebrain4.9506.310Details
BioGPS Gene Atlas207386_atcolon5.9006.310Details
BioGPS Gene Atlas207386_atpineal_day7.2406.310Details
BioGPS Gene Atlas207386_atpineal_night7.6406.310Details
BioGPS Gene Atlas207386_atretina7.2006.310Details
BioGPS Gene Atlas207386_atsmall_intestine5.6506.310Details
BioGPS NCI60207386_at7865.5326.160Details
BioGPS NCI60207386_atA1724.9656.160Details
BioGPS NCI60207386_atA2045.3216.160Details
BioGPS NCI60207386_atA3615.5446.160Details
BioGPS NCI60207386_atA4985.3386.160Details
BioGPS NCI60207386_atA5495.5416.160Details
BioGPS NCI60207386_atACC35.8246.160Details
BioGPS NCI60207386_atACHN4.8296.160Details
BioGPS NCI60207386_atALVA315.9456.160Details
BioGPS NCI60207386_atCAKI16.0746.160Details
BioGPS NCI60207386_atCCRT CEM9.5626.160Details
BioGPS NCI60207386_atCOLO2055.3496.160Details
BioGPS NCI60207386_atDLD15.2316.160Details
BioGPS NCI60207386_atDU1454.9976.160Details
BioGPS NCI60207386_atEKVX5.0846.160Details
BioGPS NCI60207386_atGM1335.5836.160Details
BioGPS NCI60207386_atGM16005.7756.160Details
BioGPS NCI60207386_atGM23135.7756.160Details
BioGPS NCI60207386_atGM23455.3706.160Details
BioGPS NCI60207386_atGM24936.2866.160Details
BioGPS NCI60207386_atGM976.8526.160Details
BioGPS NCI60207386_atHCC29984.5816.160Details
BioGPS NCI60207386_atHCT1165.3786.160Details
BioGPS NCI60207386_atHCT154.8886.160Details
BioGPS NCI60207386_atHEK 293 T-rex5.9606.160Details
BioGPS NCI60207386_atHEK 293T5.3926.160Details
BioGPS NCI60207386_atHEK2935.3806.160Details
BioGPS NCI60207386_atHELA4.8646.160Details
BioGPS NCI60207386_atHEPG25.3906.160Details
BioGPS NCI60207386_atHL605.9226.160Details
BioGPS NCI60207386_atHOP625.3886.160Details
BioGPS NCI60207386_atHOP925.1086.160Details
BioGPS NCI60207386_atHS578T5.2876.160Details
BioGPS NCI60207386_atHSG5.0726.160Details
BioGPS NCI60207386_atHT10805.2536.160Details
BioGPS NCI60207386_atHT296.0836.160Details
BioGPS NCI60207386_atIGROV15.2826.160Details
BioGPS NCI60207386_atIOSE805.3846.160Details
BioGPS NCI60207386_atJURKAT5.3416.160Details
BioGPS NCI60207386_atK5626.1116.160Details
BioGPS NCI60207386_atKM125.9956.160Details
BioGPS NCI60207386_atLN184.8776.160Details
BioGPS NCI60207386_atLNCAP5.3606.160Details
BioGPS NCI60207386_atLOX IMVI5.3576.160Details
BioGPS NCI60207386_atM145.4276.160Details
BioGPS NCI60207386_atMALME 3M6.5346.160Details
BioGPS NCI60207386_atMCF75.0966.160Details
BioGPS NCI60207386_atMD MB2315.6016.160Details
BioGPS NCI60207386_atMDA MB4356.1136.160Details
BioGPS NCI60207386_atMOLT45.7576.160Details
BioGPS NCI60207386_atNCI 4605.5646.160Details
BioGPS NCI60207386_atNCI H2265.6176.160Details
BioGPS NCI60207386_atNCI H235.3246.160Details
BioGPS NCI60207386_atNCI H322M5.3946.160Details
BioGPS NCI60207386_atNCVADR RES4.8656.160Details
BioGPS NCI60207386_atOVCAR35.8396.160Details
BioGPS NCI60207386_atOVCAR45.3276.160Details
BioGPS NCI60207386_atOVCAR55.1796.160Details
BioGPS NCI60207386_atOVCAR84.8916.160Details
BioGPS NCI60207386_atPANC15.4246.160Details
BioGPS NCI60207386_atRL75.5576.160Details
BioGPS NCI60207386_atRPMI 82265.5826.160Details
BioGPS NCI60207386_atRS118465.8826.160Details
BioGPS NCI60207386_atRXF3935.4216.160Details
BioGPS NCI60207386_atSAOS25.4336.160Details
BioGPS NCI60207386_atSF2685.3466.160Details
BioGPS NCI60207386_atSF2955.0876.160Details
BioGPS NCI60207386_atSF5394.9266.160Details
BioGPS NCI60207386_atSHSYSY+RA5.0556.160Details
BioGPS NCI60207386_atSHSYSY-RA5.2426.160Details
BioGPS NCI60207386_atSKMEL25.3626.160Details
BioGPS NCI60207386_atSKMEL285.5246.160Details
BioGPS NCI60207386_atSKMEL55.0486.160Details
BioGPS NCI60207386_atSKOV35.7406.160Details
BioGPS NCI60207386_atSN12C5.2966.160Details
BioGPS NCI60207386_atSNB194.9596.160Details
BioGPS NCI60207386_atSNB755.2476.160Details
BioGPS NCI60207386_atSR5.9286.160Details
BioGPS NCI60207386_atSW6205.5316.160Details
BioGPS NCI60207386_atT245.5636.160Details
BioGPS NCI60207386_atT3M45.7206.160Details
BioGPS NCI60207386_atTK105.3386.160Details
BioGPS NCI60207386_atU1185.1616.160Details
BioGPS NCI60207386_atU1384.8596.160Details
BioGPS NCI60207386_atU20S5.1996.160Details
BioGPS NCI60207386_atU2515.2146.160Details
BioGPS NCI60207386_atU875.0666.160Details
BioGPS NCI60207386_atUACC25781.0716.160Details
BioGPS NCI60207386_atUACC625.6186.160Details
BioGPS NCI60207386_atUO315.1416.160Details
BioGPS NCI60207386_atZR75_15.6946.160Details
BioGPS NCI60207386_atastrocytes5.4636.160Details
BioGPS NCI60207386_athuh-75.7826.160Details