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Gene ID: 1581 | CYP7A1 Antibody Resource


CYP7A1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 7, subfamily A, polypeptide 1
Uniprot: 
P22680
Protein Name: 
cholesterol 7-alpha-monooxygenase
Nucleotide: 
NM_000780
Alias: 
CP7A;CYP7;CYPVII;
Ensembl: 
ENSG00000167910
Location: 
8q11-q12
HPRD: 
00324
NCBI Gene: 
1581
MIM: 
118455

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010]
Function: 
Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
Subcellular location: 
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB05044 CYP7A1 antibody - C-terminal region (OAAB05044) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB05045 CYP7A1 antibody - N-terminal region (OAAB05045) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP60136_P050 CYP7A1 Antibody (ARP60136_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

Show all CYP7A1 antibodies


Product Images
CYP7A1 antibody - C-terminal region (OAAB05044) in K562, HepG2 cells using Western Blot

Sample Type: K562, HepG2


CYP7A1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60136 Bovine CYP7A1 antibody; Bos taurus CYP7A1 antibody E1BM29 100.0%
ARP60136 Cat CYP7A1 antibody; Felis catus CYP7A1 antibody M3W8S8 100.0%
ARP60136 Chimpanzee CYP7A1 antibody; Pan troglodytes CYP7A1 antibody H2QW73 100.0%
ARP60136 Chinese hamster CYP7A1 antibody; Cricetulus griseus CYP7A1 antibody P46634 85.0%
ARP60136 Crab-eating macaque CYP7A1 antibody; Macaca fascicularis CYP7A1 antibody B8K1S8 100.0%
ARP60136 Dog CYP7A1 antibody; Canis familiaris CYP7A1 antibody E2RLR0 100.0%
ARP60136 Dog CYP7A1 antibody; Canis familiaris CYP7A1 antibody J9P757 100.0%
ARP60136 Duckbill platypus CYP7A1 antibody; Ornithorhynchus anatinus CYP7A1 antibody F7FYW8 92.0%
ARP60136 European domestic ferret CYP7A1 antibody; Mustela putorius furo CYP7A1 antibody M3YG66 100.0%
ARP60136 Giant panda CYP7A1 antibody; Ailuropoda melanoleuca CYP7A1 antibody G1LHT2 93.0%
ARP60136 Gray short-tailed opossum CYP7A1 antibody; Monodelphis domestica CYP7A1 antibody F7CUJ1 92.0%
ARP60136 Guinea pig CYP7A1 antibody; Cavia porcellus CYP7A1 antibody D2X3G2 93.0%
ARP60136 Guinea pig CYP7A1 antibody; Cavia porcellus CYP7A1 antibody H0V0R7 93.0%
ARP60136 Horse CYP7A1 antibody; Equus caballus CYP7A1 antibody F6RH93 100.0%
ARP60136 Human CYP7A1 antibody; Homo sapiens CYP7A1 antibody P22680 100.0%
ARP60136 Mouse CYP7A1 antibody; Mus musculus CYP7A1 antibody Q64505 86.0%
ARP60136 Mouse CYP7A1 antibody; Mus musculus CYP7A1 antibody A1L3S6 86.0%
ARP60136 Pig CYP7A1 antibody; Sus scrofa CYP7A1 antibody F1RT71 100.0%
ARP60136 Pig CYP7A1 antibody; Sus scrofa CYP7A1 antibody O46491 100.0%
ARP60136 Rabbit CYP7A1 antibody; Oryctolagus cuniculus CYP7A1 antibody P51542 93.0%
ARP60136 Rat CYP7A1 antibody; Rattus norvegicus CYP7A1 antibody P18125 86.0%
ARP60136 Rhesus macaque CYP7A1 antibody; Macaca mulatta CYP7A1 antibody F7HS30 100.0%
ARP60136 Small-eared galago CYP7A1 antibody; Otolemur garnettii CYP7A1 antibody H0WRQ4 100.0%
ARP60136 Sumatran orangutan CYP7A1 antibody; Pongo abelii CYP7A1 antibody H2PQD1 100.0%
ARP60136 Tasmanian devil CYP7A1 antibody; Sarcophilus harrisii CYP7A1 antibody G3WJ84 92.0%
ARP60136 Thirteen-lined ground squirrel CYP7A1 antibody; Spermophilus tridecemlineatus CYP7A1 antibody I3M871 93.0%
ARP60136 White-tufted-ear marmoset CYP7A1 antibody; Callithrix jacchus CYP7A1 antibody F7HJP5 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207406_at721_B_lymphoblasts7.4507.160Details
BioGPS Gene Atlas207406_atAdipocyte6.7007.160Details
BioGPS Gene Atlas207406_atAdrenalCortex8.6007.160Details
BioGPS Gene Atlas207406_atAdrenalgland6.2007.160Details
BioGPS Gene Atlas207406_atAmygdala6.8007.160Details
BioGPS Gene Atlas207406_atAppendix9.4507.160Details
BioGPS Gene Atlas207406_atAtrioventricularNode6.9507.160Details
BioGPS Gene Atlas207406_atBDCA4+_DentriticCells6.8507.160Details
BioGPS Gene Atlas207406_atBonemarrow7.5507.160Details
BioGPS Gene Atlas207406_atBronchialEpithelialCells6.5507.160Details
BioGPS Gene Atlas207406_atCD105+_Endothelial6.7507.160Details
BioGPS Gene Atlas207406_atCD14+_Monocytes7.3007.160Details
BioGPS Gene Atlas207406_atCD19+_BCells(neg._sel.)7.3507.160Details
BioGPS Gene Atlas207406_atCD33+_Myeloid8.4007.160Details
BioGPS Gene Atlas207406_atCD34+8.2007.160Details
BioGPS Gene Atlas207406_atCD4+_Tcells6.9507.160Details
BioGPS Gene Atlas207406_atCD56+_NKCells7.7007.160Details
BioGPS Gene Atlas207406_atCD71+_EarlyErythroid6.6007.160Details
BioGPS Gene Atlas207406_atCD8+_Tcells6.0507.160Details
BioGPS Gene Atlas207406_atCardiacMyocytes11.6007.160Details
BioGPS Gene Atlas207406_atCaudatenucleus6.1507.160Details
BioGPS Gene Atlas207406_atCerebellum5.7007.160Details
BioGPS Gene Atlas207406_atCerebellumPeduncles8.3507.160Details
BioGPS Gene Atlas207406_atCiliaryGanglion6.0507.160Details
BioGPS Gene Atlas207406_atCingulateCortex7.3007.160Details
BioGPS Gene Atlas207406_atColorectaladenocarcinoma6.8507.160Details
BioGPS Gene Atlas207406_atDorsalRootGanglion6.3507.160Details
BioGPS Gene Atlas207406_atFetalThyroid6.9007.160Details
BioGPS Gene Atlas207406_atFetalbrain6.5507.160Details
BioGPS Gene Atlas207406_atFetalliver6.1507.160Details
BioGPS Gene Atlas207406_atFetallung5.3007.160Details
BioGPS Gene Atlas207406_atGlobusPallidus5.5007.160Details
BioGPS Gene Atlas207406_atHeart11.0507.160Details
BioGPS Gene Atlas207406_atHypothalamus7.0007.160Details
BioGPS Gene Atlas207406_atKidney6.2507.160Details
BioGPS Gene Atlas207406_atLeukemia_chronicMyelogenousK-5626.1007.160Details
BioGPS Gene Atlas207406_atLeukemia_promyelocytic-HL-606.0507.160Details
BioGPS Gene Atlas207406_atLeukemialymphoblastic(MOLT-4)5.2007.160Details
BioGPS Gene Atlas207406_atLiver10.7507.160Details
BioGPS Gene Atlas207406_atLung7.4007.160Details
BioGPS Gene Atlas207406_atLymphnode5.6507.160Details
BioGPS Gene Atlas207406_atLymphoma_burkitts(Daudi)9.1507.160Details
BioGPS Gene Atlas207406_atLymphoma_burkitts(Raji)10.6507.160Details
BioGPS Gene Atlas207406_atMedullaOblongata6.0507.160Details
BioGPS Gene Atlas207406_atOccipitalLobe6.1007.160Details
BioGPS Gene Atlas207406_atOlfactoryBulb5.3007.160Details
BioGPS Gene Atlas207406_atOvary5.1007.160Details
BioGPS Gene Atlas207406_atPancreas5.8007.160Details
BioGPS Gene Atlas207406_atPancreaticIslet7.4507.160Details
BioGPS Gene Atlas207406_atParietalLobe7.8007.160Details
BioGPS Gene Atlas207406_atPituitary8.0007.160Details
BioGPS Gene Atlas207406_atPlacenta6.7507.160Details
BioGPS Gene Atlas207406_atPons6.9507.160Details
BioGPS Gene Atlas207406_atPrefrontalCortex8.1007.160Details
BioGPS Gene Atlas207406_atProstate7.7507.160Details
BioGPS Gene Atlas207406_atSalivarygland5.8007.160Details
BioGPS Gene Atlas207406_atSkeletalMuscle10.0507.160Details
BioGPS Gene Atlas207406_atSkin6.2507.160Details
BioGPS Gene Atlas207406_atSmoothMuscle7.7007.160Details
BioGPS Gene Atlas207406_atSpinalcord7.2507.160Details
BioGPS Gene Atlas207406_atSubthalamicNucleus6.6507.160Details
BioGPS Gene Atlas207406_atSuperiorCervicalGanglion10.1507.160Details
BioGPS Gene Atlas207406_atTemporalLobe6.6007.160Details
BioGPS Gene Atlas207406_atTestis5.8507.160Details
BioGPS Gene Atlas207406_atTestisGermCell5.4507.160Details
BioGPS Gene Atlas207406_atTestisIntersitial5.9007.160Details
BioGPS Gene Atlas207406_atTestisLeydigCell7.2007.160Details
BioGPS Gene Atlas207406_atTestisSeminiferousTubule5.8007.160Details
BioGPS Gene Atlas207406_atThalamus7.2007.160Details
BioGPS Gene Atlas207406_atThymus5.1007.160Details
BioGPS Gene Atlas207406_atThyroid8.1007.160Details
BioGPS Gene Atlas207406_atTongue7.7007.160Details
BioGPS Gene Atlas207406_atTonsil6.8007.160Details
BioGPS Gene Atlas207406_atTrachea5.6507.160Details
BioGPS Gene Atlas207406_atTrigeminalGanglion8.7007.160Details
BioGPS Gene Atlas207406_atUterus5.3007.160Details
BioGPS Gene Atlas207406_atUterusCorpus7.0007.160Details
BioGPS Gene Atlas207406_atWholeBlood7.4007.160Details
BioGPS Gene Atlas207406_atWholebrain5.4007.160Details
BioGPS Gene Atlas207406_atcolon6.9007.160Details
BioGPS Gene Atlas207406_atpineal_day8.3407.160Details
BioGPS Gene Atlas207406_atpineal_night8.2407.160Details
BioGPS Gene Atlas207406_atretina8.2507.160Details
BioGPS Gene Atlas207406_atsmall_intestine6.5007.160Details
BioGPS NCI60207406_at7867.3827.040Details
BioGPS NCI60207406_atA1726.2077.040Details
BioGPS NCI60207406_atA2046.8407.040Details
BioGPS NCI60207406_atA3617.0717.040Details
BioGPS NCI60207406_atA4986.8627.040Details
BioGPS NCI60207406_atA5497.1707.040Details
BioGPS NCI60207406_atACC37.9757.040Details
BioGPS NCI60207406_atACHN5.9717.040Details
BioGPS NCI60207406_atALVA318.4307.040Details
BioGPS NCI60207406_atCAKI17.7087.040Details
BioGPS NCI60207406_atCCRT CEM11.1027.040Details
BioGPS NCI60207406_atCOLO2057.0127.040Details
BioGPS NCI60207406_atDLD16.7267.040Details
BioGPS NCI60207406_atDU1456.2897.040Details
BioGPS NCI60207406_atEKVX6.3157.040Details
BioGPS NCI60207406_atGM1337.3447.040Details
BioGPS NCI60207406_atGM16007.8937.040Details
BioGPS NCI60207406_atGM23137.3497.040Details
BioGPS NCI60207406_atGM23456.8497.040Details
BioGPS NCI60207406_atGM24938.0377.040Details
BioGPS NCI60207406_atGM9710.3867.040Details
BioGPS NCI60207406_atHCC29985.6287.040Details
BioGPS NCI60207406_atHCT1166.9747.040Details
BioGPS NCI60207406_atHCT156.1217.040Details
BioGPS NCI60207406_atHEK 293 T-rex7.6627.040Details
BioGPS NCI60207406_atHEK 293T6.8387.040Details
BioGPS NCI60207406_atHEK2936.7827.040Details
BioGPS NCI60207406_atHELA6.0727.040Details
BioGPS NCI60207406_atHEPG27.0777.040Details
BioGPS NCI60207406_atHL608.1597.040Details
BioGPS NCI60207406_atHOP626.9307.040Details
BioGPS NCI60207406_atHOP926.4667.040Details
BioGPS NCI60207406_atHS578T6.7537.040Details
BioGPS NCI60207406_atHSG6.3647.040Details
BioGPS NCI60207406_atHT10806.7107.040Details
BioGPS NCI60207406_atHT298.5727.040Details
BioGPS NCI60207406_atIGROV16.7297.040Details
BioGPS NCI60207406_atIOSE806.8597.040Details
BioGPS NCI60207406_atJURKAT6.8597.040Details
BioGPS NCI60207406_atK5628.4377.040Details
BioGPS NCI60207406_atKM127.6617.040Details
BioGPS NCI60207406_atLN185.9817.040Details
BioGPS NCI60207406_atLNCAP6.9337.040Details
BioGPS NCI60207406_atLOX IMVI6.8337.040Details
BioGPS NCI60207406_atM146.9377.040Details
BioGPS NCI60207406_atMALME 3M8.1357.040Details
BioGPS NCI60207406_atMCF76.5027.040Details
BioGPS NCI60207406_atMD MB2317.1797.040Details
BioGPS NCI60207406_atMDA MB4358.5207.040Details
BioGPS NCI60207406_atMOLT47.7017.040Details
BioGPS NCI60207406_atNCI 4607.2577.040Details
BioGPS NCI60207406_atNCI H2267.4077.040Details
BioGPS NCI60207406_atNCI H236.8557.040Details
BioGPS NCI60207406_atNCI H322M6.8377.040Details
BioGPS NCI60207406_atNCVADR RES6.0587.040Details
BioGPS NCI60207406_atOVCAR37.9247.040Details
BioGPS NCI60207406_atOVCAR46.8107.040Details
BioGPS NCI60207406_atOVCAR56.5777.040Details
BioGPS NCI60207406_atOVCAR86.0797.040Details
BioGPS NCI60207406_atPANC17.0967.040Details
BioGPS NCI60207406_atRL77.3217.040Details
BioGPS NCI60207406_atRPMI 82267.4047.040Details
BioGPS NCI60207406_atRS118467.9217.040Details
BioGPS NCI60207406_atRXF3936.8987.040Details
BioGPS NCI60207406_atSAOS27.0167.040Details
BioGPS NCI60207406_atSF2686.8377.040Details
BioGPS NCI60207406_atSF2956.4847.040Details
BioGPS NCI60207406_atSF5396.0577.040Details
BioGPS NCI60207406_atSHSYSY+RA6.3737.040Details
BioGPS NCI60207406_atSHSYSY-RA6.6877.040Details
BioGPS NCI60207406_atSKMEL26.8517.040Details
BioGPS NCI60207406_atSKMEL286.9187.040Details
BioGPS NCI60207406_atSKMEL56.2627.040Details
BioGPS NCI60207406_atSKOV37.5897.040Details
BioGPS NCI60207406_atSN12C6.7987.040Details
BioGPS NCI60207406_atSNB196.1397.040Details
BioGPS NCI60207406_atSNB756.6927.040Details
BioGPS NCI60207406_atSR7.5167.040Details
BioGPS NCI60207406_atSW6207.3077.040Details
BioGPS NCI60207406_atT247.2087.040Details
BioGPS NCI60207406_atT3M47.7127.040Details
BioGPS NCI60207406_atTK106.7897.040Details
BioGPS NCI60207406_atU1186.4717.040Details
BioGPS NCI60207406_atU1385.9887.040Details
BioGPS NCI60207406_atU20S6.6367.040Details
BioGPS NCI60207406_atU2516.6707.040Details
BioGPS NCI60207406_atU876.3837.040Details
BioGPS NCI60207406_atUACC2576.4827.040Details
BioGPS NCI60207406_atUACC627.1457.040Details
BioGPS NCI60207406_atUO316.4407.040Details
BioGPS NCI60207406_atZR75_17.5777.040Details
BioGPS NCI60207406_atastrocytes7.0057.040Details
BioGPS NCI60207406_athuh-77.4007.040Details