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Gene ID: 285440 | CYP4V2 Antibody Resource


CYP4V2 Antibody Resource
Gene Full Name: 
cytochrome P450, family 4, subfamily V, polypeptide 2
Uniprot: 
Q6ZWL3
Protein Name: 
cytochrome P450 4V2
Nucleotide: 
XM_005262935
Alias: 
BCD;CYP4AH1;
Ensembl: 
Location: 
4q35.2
HPRD: 
16777
NCBI Gene: 
285440
MIM: 
608614

Summary: 
This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids. Mutations in this gene result in Bietti crystalline corneoretinal dystrophy. [provided by RefSeq, Jul 2008]
Function: 
Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12). May have a role in fatty acid and steroid metabolism in the eye.
Subcellular location: 
Endoplasmic reticulum membrane; Single-pass membrane protein Potential.
PTM: 
Disease: 
Bietti crystalline corneoretinal dystrophy (BCD) [MIM:210370]: An autosomal recessive ocular disease characterized by retinal degeneration and marginal corneal dystrophy. Typical features include multiple glistening intraretinal crystals scattered over the fundus, a characteristic degeneration of the retina, and sclerosis of the choroidal vessels, ultimately resulting in progressive night blindness and constriction of the visual field. Most patients have similar crystals at the corneoscleral limbus. Patients develop decreased vision, nyctalopia, and paracentral scotomata between the 2nd and 4th decade of life. Later, they develop peripheral visual field loss and marked visual impairment, usually progressing to legal blindness by the 5th or 6th decade of life. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP55993_P050 CYP4V2 antibody - middle region (ARP55993_P050) Polyclonal Bovine, Dog, Guinea pig, Pig, Rabbit WB 50ug $289 Details
Polyclonal Antibody ARP55992_P050 CYP4V2 Antibody (ARP55992_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB12970 CYP4V2 antibody - C - terminal region (OAAB12970) Human WB 400ul $289 Details
Polyclonal Antibody OAEC03332 CYP4V2 Antibody (OAEC03332) Human WB, ELISA 100ug $229 Details
Polyclonal Antibody OAAF04604 CYP4V2 Antibody (OAAF04604) Polyclonal Human WB, ELISA 100 ug $289 Details

Show all CYP4V2 antibodies


Product Images
CYP4V2 antibody - middle region (ARP55993_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat

CYP4V2 antibody - C - terminal region (OAAB12970) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

CYP4V2 Antibody (OAAF04604) in Jurkat cells using Western Blot

Sample Type: Jurkat

CYP4V2 Antibody (OAEC03332) in Jurkat cells using Western Blot

Sample Type: Jurkat


CYP4V2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP55993 African clawed frog CYP4V2 antibody; Xenopus laevis CYP4V2 antibody Q6GMD7 83.0%
ARP55992 Bovine CYP4V2 antibody; Bos taurus CYP4V2 antibody Q3MHQ3 86.0%
ARP55992 Bovine CYP4V2 antibody; Bos taurus CYP4V2 antibody F1N3Z7 86.0%
ARP55993 Bovine CYP4V2 antibody; Bos taurus CYP4V2 antibody Q3MHQ3 85.0%
ARP55993 Bovine CYP4V2 antibody; Bos taurus CYP4V2 antibody F1N3Z7 85.0%
ARP55993 Cat CYP4V2 antibody; Felis catus CYP4V2 antibody M3VWV1 93.0%
ARP55992 Cat CYP4V2 antibody; Felis catus CYP4V2 antibody M3VWV1 79.0%
ARP55993 Chicken CYP4V2 antibody; Gallus gallus CYP4V2 antibody E1BYW5 85.0%
ARP55992 Chimpanzee CYP4V2 antibody; Pan troglodytes CYP4V2 antibody H2QQJ3 100.0%
ARP55992 Chimpanzee CYP4V2 antibody; Pan troglodytes CYP4V2 antibody H2R9W8 100.0%
ARP55993 Chimpanzee CYP4V2 antibody; Pan troglodytes CYP4V2 antibody H2QQJ3 93.0%
ARP55993 Chimpanzee CYP4V2 antibody; Pan troglodytes CYP4V2 antibody H2R9W8 93.0%
ARP55993 Dog CYP4V2 antibody; Canis familiaris CYP4V2 antibody F1PNR5 93.0%
ARP55992 Dog CYP4V2 antibody; Canis familiaris CYP4V2 antibody F1PNR5 79.0%
ARP55993 Domestic duck CYP4V2 antibody; Anas platyrhynchos CYP4V2 antibody R0KF96 85.0%
ARP55992 Domestic duck CYP4V2 antibody; Anas platyrhynchos CYP4V2 antibody R0KF96 79.0%
ARP55993 European domestic ferret CYP4V2 antibody; Mustela putorius furo CYP4V2 antibody M3YIQ3 93.0%
ARP55992 European domestic ferret CYP4V2 antibody; Mustela putorius furo CYP4V2 antibody M3YIQ3 79.0%
ARP55992 Giant panda CYP4V2 antibody; Ailuropoda melanoleuca CYP4V2 antibody G1LEV6 93.0%
ARP55993 Giant panda CYP4V2 antibody; Ailuropoda melanoleuca CYP4V2 antibody G1LEV6 93.0%
ARP55993 Horse CYP4V2 antibody; Equus caballus CYP4V2 antibody F6X2D4 92.0%
ARP55992 Horse CYP4V2 antibody; Equus caballus CYP4V2 antibody F6X2D4 86.0%
ARP55992 Human CYP4V2 antibody; Homo sapiens CYP4V2 antibody Q6ZWL3-2 100.0%
ARP55993 Human CYP4V2 antibody; Homo sapiens CYP4V2 antibody Q6ZWL3-2 100.0%
ARP55992 Human CYP4V2 antibody; Homo sapiens CYP4V2 antibody Q6ZWL3 100.0%
ARP55993 Human CYP4V2 antibody; Homo sapiens CYP4V2 antibody Q6ZWL3 100.0%
ARP55993 Indian medaka CYP4V2 antibody; Oryzias melastigma CYP4V2 antibody R9S3E3 83.0%
ARP55993 Mouse CYP4V2 antibody; Mus musculus CYP4V2 antibody Q9DBW0 92.0%
ARP55992 Mouse CYP4V2 antibody; Mus musculus CYP4V2 antibody Q9DBW0 86.0%
ARP55992 Pig CYP4V2 antibody; Sus scrofa CYP4V2 antibody A7KZS1 86.0%
ARP55992 Pig CYP4V2 antibody; Sus scrofa CYP4V2 antibody F1RZN0 86.0%
ARP55993 Pig CYP4V2 antibody; Sus scrofa CYP4V2 antibody A7KZS2 85.0%
ARP55993 Rabbit CYP4V2 antibody; Oryctolagus cuniculus CYP4V2 antibody G1T118 100.0%
ARP55992 Rabbit CYP4V2 antibody; Oryctolagus cuniculus CYP4V2 antibody G1T118 86.0%
ARP55993 Rat CYP4V2 antibody; Rattus norvegicus CYP4V2 antibody A2RRT9 93.0%
ARP55992 Rat CYP4V2 antibody; Rattus norvegicus CYP4V2 antibody A2RRT9 86.0%
ARP55992 Rhesus macaque CYP4V2 antibody; Macaca mulatta CYP4V2 antibody F6PJB6 100.0%
ARP55993 Rhesus macaque CYP4V2 antibody; Macaca mulatta CYP4V2 antibody F6PJB6 100.0%
ARP55992 Rhesus macaque CYP4V2 antibody; Macaca mulatta CYP4V2 antibody F6PJC3 100.0%
ARP55993 Rhesus macaque CYP4V2 antibody; Macaca mulatta CYP4V2 antibody F6PJC3 100.0%
ARP55993 Small-eared galago CYP4V2 antibody; Otolemur garnettii CYP4V2 antibody H0WJV1 100.0%
ARP55992 Small-eared galago CYP4V2 antibody; Otolemur garnettii CYP4V2 antibody H0WJV1 79.0%
ARP55992 Sumatran orangutan CYP4V2 antibody; Pongo abelii CYP4V2 antibody Q5RCN6 100.0%
ARP55993 Sumatran orangutan CYP4V2 antibody; Pongo abelii CYP4V2 antibody Q5RCN6 100.0%
ARP55993 Tasmanian devil CYP4V2 antibody; Sarcophilus harrisii CYP4V2 antibody G3VV00 86.0%
ARP55993 Thirteen-lined ground squirrel CYP4V2 antibody; Spermophilus tridecemlineatus CYP4V2 antibody I3MVZ5 100.0%
ARP55992 Thirteen-lined ground squirrel CYP4V2 antibody; Spermophilus tridecemlineatus CYP4V2 antibody I3MVZ5 86.0%
ARP55993 Western clawed frog CYP4V2 antibody; Xenopus tropicalis CYP4V2 antibody Q08D20 92.0%
ARP55993 Western clawed frog CYP4V2 antibody; Xenopus tropicalis CYP4V2 antibody F6YR74 92.0%
ARP55993 Western clawed frog CYP4V2 antibody; Xenopus tropicalis CYP4V2 antibody F6YRB2 92.0%
ARP55992 White-tufted-ear marmoset CYP4V2 antibody; Callithrix jacchus CYP4V2 antibody F6ZDK0 100.0%
ARP55993 White-tufted-ear marmoset CYP4V2 antibody; Callithrix jacchus CYP4V2 antibody F6ZDK0 93.0%
ARP55993 Zebra finch CYP4V2 antibody; Taeniopygia guttata CYP4V2 antibody H0Z989 85.0%

Tissue & Cell Line Gene Expression Data