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Gene ID: 10858 | CYP46A1 Antibody Resource


CYP46A1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 46, subfamily A, polypeptide 1
Uniprot: 
Q9Y6A2
Protein Name: 
cholesterol 24-hydroxylase
Nucleotide: 
NM_006668
Alias: 
CP46;CYP46;
Ensembl: 
ENSG00000036530
Location: 
14q32.1
HPRD: 
04970
NCBI Gene: 
10858
MIM: 
604087

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
Function: 
Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole.
Subcellular location: 
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP43670_P050 CYP46A1 antibody - C-terminal region (ARP43670_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rat WB 50ug $289 Details
Polyclonal Antibody OASA05913 CYP46A1 antibody - C-terminal region (OASA05913) Human ELISA, WB 0.1ml $410 Details
Polyclonal Antibody OAAB05324 CYP46A1 antibody - N-terminal region (OAAB05324) Human WB, FC, IHC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB05325 CYP46A1 antibody - center region (OAAB05325) Human; Mouse WB, FC, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP43669_P050 CYP46A1 Antibody (ARP43669_P050) Polyclonal Bovine, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

Show all CYP46A1 antibodies


Product Images
CYP46A1 antibody - C-terminal region (ARP43670_P050) in Hum. Adult Placenta cells using Western Blot

Sample Type: Hum. Adult Placenta

CYP46A1 antibody - C-terminal region (ARP43670_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2


CYP46A1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP43669 African clawed frog CYP46A1 antibody; Xenopus laevis CYP46A1 antibody Q7SYY2 83.0%
ARP43670 African clawed frog CYP46A1 antibody; Xenopus laevis CYP46A1 antibody Q7SYY2 83.0%
ARP43669 Bovine CYP46A1 antibody; Bos taurus CYP46A1 antibody Q08DD0 100.0%
ARP43670 Bovine CYP46A1 antibody; Bos taurus CYP46A1 antibody Q08DD0 100.0%
ARP43670 Cat CYP46A1 antibody; Felis catus CYP46A1 antibody M3VWH5 100.0%
ARP43670 Chicken CYP46A1 antibody; Gallus gallus CYP46A1 antibody F1NEB6 83.0%
ARP43670 Chimpanzee CYP46A1 antibody; Pan troglodytes CYP46A1 antibody H2Q8X0 100.0%
ARP43670 Chinese softshell turtle CYP46A1 antibody; Pelodiscus sinensis CYP46A1 antibody K7G7A4 83.0%
ARP43670 Chinese softshell turtle CYP46A1 antibody; Pelodiscus sinensis CYP46A1 antibody K7G7F1 83.0%
ARP43670 Dog CYP46A1 antibody; Canis familiaris CYP46A1 antibody F1PBD7 100.0%
ARP43670 Domestic duck CYP46A1 antibody; Anas platyrhynchos CYP46A1 antibody U3IAU6 100.0%
ARP43670 European domestic ferret CYP46A1 antibody; Mustela putorius furo CYP46A1 antibody M3XV36 100.0%
ARP43670 Giant panda CYP46A1 antibody; Ailuropoda melanoleuca CYP46A1 antibody G1LY38 100.0%
ARP43669 Golden hamster CYP46A1 antibody; Mesocricetus auratus CYP46A1 antibody C4PBL8 100.0%
ARP43670 Golden hamster CYP46A1 antibody; Mesocricetus auratus CYP46A1 antibody C4PBL8 100.0%
ARP43670 Horse CYP46A1 antibody; Equus caballus CYP46A1 antibody F6W0L2 100.0%
ARP43670 Human CYP46A1 antibody; Homo sapiens CYP46A1 antibody H0Y3G0 100.0%
ARP43670 Human CYP46A1 antibody; Homo sapiens CYP46A1 antibody Q8N2B0 100.0%
ARP43669 Human CYP46A1 antibody; Homo sapiens CYP46A1 antibody Q9Y6A2 100.0%
ARP43670 Human CYP46A1 antibody; Homo sapiens CYP46A1 antibody Q9Y6A2 100.0%
ARP43670 Human CYP46A1 antibody; Homo sapiens CYP46A1 antibody B4DHP8 100.0%
ARP43669 Human CYP46A1 antibody; Homo sapiens CYP46A1 antibody G3V366 100.0%
ARP43669 Mouse CYP46A1 antibody; Mus musculus CYP46A1 antibody Q3US73 100.0%
ARP43670 Mouse CYP46A1 antibody; Mus musculus CYP46A1 antibody Q3US73 100.0%
ARP43669 Mouse CYP46A1 antibody; Mus musculus CYP46A1 antibody Q9WVK8 100.0%
ARP43670 Mouse CYP46A1 antibody; Mus musculus CYP46A1 antibody Q9WVK8 100.0%
ARP43669 Pig CYP46A1 antibody; Sus scrofa CYP46A1 antibody F1SAQ2 100.0%
ARP43670 Pig CYP46A1 antibody; Sus scrofa CYP46A1 antibody F1SAQ2 100.0%
ARP43669 Rabbit CYP46A1 antibody; Oryctolagus cuniculus CYP46A1 antibody G1TJV6 100.0%
ARP43669 Rat CYP46A1 antibody; Rattus norvegicus CYP46A1 antibody B1WC64 100.0%
ARP43670 Rat CYP46A1 antibody; Rattus norvegicus CYP46A1 antibody B1WC64 100.0%
ARP43670 Rat CYP46A1 antibody; Rattus norvegicus CYP46A1 antibody F7EN52 100.0%
ARP43669 Rhesus macaque CYP46A1 antibody; Macaca mulatta CYP46A1 antibody I2CYF7 100.0%
ARP43670 Rhesus macaque CYP46A1 antibody; Macaca mulatta CYP46A1 antibody I2CYF7 100.0%
ARP43669 Rhesus macaque CYP46A1 antibody; Macaca mulatta CYP46A1 antibody H9F9I0 100.0%
ARP43670 Rhesus macaque CYP46A1 antibody; Macaca mulatta CYP46A1 antibody H9F9I0 100.0%
ARP43670 Rhesus macaque CYP46A1 antibody; Macaca mulatta CYP46A1 antibody F7H8G4 100.0%
ARP43669 Small-eared galago CYP46A1 antibody; Otolemur garnettii CYP46A1 antibody H0WSX2 100.0%
ARP43670 Small-eared galago CYP46A1 antibody; Otolemur garnettii CYP46A1 antibody H0WSX2 93.0%
ARP43669 Spotted green pufferfish CYP46A1 antibody; Tetraodon nigroviridis CYP46A1 antibody H3CWE3 83.0%
ARP43670 Sumatran orangutan CYP46A1 antibody; Pongo abelii CYP46A1 antibody H2NM86 100.0%
ARP43669 Sumatran orangutan CYP46A1 antibody; Pongo abelii CYP46A1 antibody H2NM86 79.0%
ARP43669 Tasmanian devil CYP46A1 antibody; Sarcophilus harrisii CYP46A1 antibody G3VB97 85.0%
ARP43669 Thirteen-lined ground squirrel CYP46A1 antibody; Spermophilus tridecemlineatus CYP46A1 antibody I3LYY7 100.0%
ARP43670 Thirteen-lined ground squirrel CYP46A1 antibody; Spermophilus tridecemlineatus CYP46A1 antibody I3LYY7 100.0%
ARP43670 Western clawed frog CYP46A1 antibody; Xenopus tropicalis CYP46A1 antibody F7DN88 100.0%
ARP43669 Western clawed frog CYP46A1 antibody; Xenopus tropicalis CYP46A1 antibody F6QGU1 89.0%
ARP43669 Western clawed frog CYP46A1 antibody; Xenopus tropicalis CYP46A1 antibody F7D0N4 89.0%
ARP43669 Western clawed frog CYP46A1 antibody; Xenopus tropicalis CYP46A1 antibody F7DN88 89.0%
ARP43669 Western clawed frog CYP46A1 antibody; Xenopus tropicalis CYP46A1 antibody Q0P4I6 83.0%
ARP43669 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3CJ69 100.0%
ARP43670 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3CJ69 100.0%
ARP43669 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3DP22 100.0%
ARP43670 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3DP22 100.0%
ARP43669 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3DWT9 100.0%
ARP43670 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3DWT9 100.0%
ARP43669 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3E8W7 100.0%
ARP43670 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody U3E8W7 100.0%
ARP43669 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody F6PP29 100.0%
ARP43670 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody F6PP29 100.0%
ARP43670 White-tufted-ear marmoset CYP46A1 antibody; Callithrix jacchus CYP46A1 antibody F6PZW5 100.0%
ARP43669 Zebrafish CYP46A1 antibody; Danio rerio CYP46A1 antibody Q504G3 83.0%
ARP43669 Zebrafish CYP46A1 antibody; Danio rerio CYP46A1 antibody Q6DHE1 83.0%
ARP43669 Zebrafish CYP46A1 antibody; Danio rerio CYP46A1 antibody A5WWJ0 83.0%
ARP43669 Zebrafish CYP46A1 antibody; Danio rerio CYP46A1 antibody E7F289 83.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas220331_at721_B_lymphoblasts5.55067.180Details
BioGPS Gene Atlas220331_atAdipocyte4.50067.180Details
BioGPS Gene Atlas220331_atAdrenalCortex4.50067.180Details
BioGPS Gene Atlas220331_atAdrenalgland3.85067.180Details
BioGPS Gene Atlas220331_atAmygdala569.60067.180Details
BioGPS Gene Atlas220331_atAppendix4.55067.180Details
BioGPS Gene Atlas220331_atAtrioventricularNode3.40067.180Details
BioGPS Gene Atlas220331_atBDCA4+_DentriticCells26.90067.180Details
BioGPS Gene Atlas220331_atBonemarrow4.55067.180Details
BioGPS Gene Atlas220331_atBronchialEpithelialCells4.50067.180Details
BioGPS Gene Atlas220331_atCD105+_Endothelial4.60067.180Details
BioGPS Gene Atlas220331_atCD14+_Monocytes4.80067.180Details
BioGPS Gene Atlas220331_atCD19+_BCells(neg._sel.)4.90067.180Details
BioGPS Gene Atlas220331_atCD33+_Myeloid5.80067.180Details
BioGPS Gene Atlas220331_atCD34+5.80067.180Details
BioGPS Gene Atlas220331_atCD4+_Tcells5.20067.180Details
BioGPS Gene Atlas220331_atCD56+_NKCells5.20067.180Details
BioGPS Gene Atlas220331_atCD71+_EarlyErythroid4.25067.180Details
BioGPS Gene Atlas220331_atCD8+_Tcells4.30067.180Details
BioGPS Gene Atlas220331_atCardiacMyocytes6.10067.180Details
BioGPS Gene Atlas220331_atCaudatenucleus1089.85067.180Details
BioGPS Gene Atlas220331_atCerebellum9.40067.180Details
BioGPS Gene Atlas220331_atCerebellumPeduncles6.10067.180Details
BioGPS Gene Atlas220331_atCiliaryGanglion3.00067.180Details
BioGPS Gene Atlas220331_atCingulateCortex258.55067.180Details
BioGPS Gene Atlas220331_atColorectaladenocarcinoma4.55067.180Details
BioGPS Gene Atlas220331_atDorsalRootGanglion3.45067.180Details
BioGPS Gene Atlas220331_atFetalThyroid4.40067.180Details
BioGPS Gene Atlas220331_atFetalbrain19.60067.180Details
BioGPS Gene Atlas220331_atFetalliver4.00067.180Details
BioGPS Gene Atlas220331_atFetallung3.40067.180Details
BioGPS Gene Atlas220331_atGlobusPallidus124.85067.180Details
BioGPS Gene Atlas220331_atHeart6.65067.180Details
BioGPS Gene Atlas220331_atHypothalamus293.40067.180Details
BioGPS Gene Atlas220331_atKidney3.65067.180Details
BioGPS Gene Atlas220331_atLeukemia_chronicMyelogenousK-5624.10067.180Details
BioGPS Gene Atlas220331_atLeukemia_promyelocytic-HL-604.05067.180Details
BioGPS Gene Atlas220331_atLeukemialymphoblastic(MOLT-4)3.65067.180Details
BioGPS Gene Atlas220331_atLiver6.15067.180Details
BioGPS Gene Atlas220331_atLung5.15067.180Details
BioGPS Gene Atlas220331_atLymphnode3.65067.180Details
BioGPS Gene Atlas220331_atLymphoma_burkitts(Daudi)5.75067.180Details
BioGPS Gene Atlas220331_atLymphoma_burkitts(Raji)9.20067.180Details
BioGPS Gene Atlas220331_atMedullaOblongata306.90067.180Details
BioGPS Gene Atlas220331_atOccipitalLobe333.50067.180Details
BioGPS Gene Atlas220331_atOlfactoryBulb3.55067.180Details
BioGPS Gene Atlas220331_atOvary3.00067.180Details
BioGPS Gene Atlas220331_atPancreas3.65067.180Details
BioGPS Gene Atlas220331_atPancreaticIslet4.85067.180Details
BioGPS Gene Atlas220331_atParietalLobe236.35067.180Details
BioGPS Gene Atlas220331_atPituitary10.05067.180Details
BioGPS Gene Atlas220331_atPlacenta4.25067.180Details
BioGPS Gene Atlas220331_atPons230.45067.180Details
BioGPS Gene Atlas220331_atPrefrontalCortex560.00067.180Details
BioGPS Gene Atlas220331_atProstate5.30067.180Details
BioGPS Gene Atlas220331_atSalivarygland3.65067.180Details
BioGPS Gene Atlas220331_atSkeletalMuscle5.40067.180Details
BioGPS Gene Atlas220331_atSkin3.45067.180Details
BioGPS Gene Atlas220331_atSmoothMuscle5.10067.180Details
BioGPS Gene Atlas220331_atSpinalcord29.40067.180Details
BioGPS Gene Atlas220331_atSubthalamicNucleus176.20067.180Details
BioGPS Gene Atlas220331_atSuperiorCervicalGanglion5.55067.180Details
BioGPS Gene Atlas220331_atTemporalLobe232.15067.180Details
BioGPS Gene Atlas220331_atTestis3.90067.180Details
BioGPS Gene Atlas220331_atTestisGermCell3.80067.180Details
BioGPS Gene Atlas220331_atTestisIntersitial3.80067.180Details
BioGPS Gene Atlas220331_atTestisLeydigCell4.50067.180Details
BioGPS Gene Atlas220331_atTestisSeminiferousTubule3.90067.180Details
BioGPS Gene Atlas220331_atThalamus227.10067.180Details
BioGPS Gene Atlas220331_atThymus3.55067.180Details
BioGPS Gene Atlas220331_atThyroid5.85067.180Details
BioGPS Gene Atlas220331_atTongue4.45067.180Details
BioGPS Gene Atlas220331_atTonsil4.45067.180Details
BioGPS Gene Atlas220331_atTrachea3.85067.180Details
BioGPS Gene Atlas220331_atTrigeminalGanglion4.60067.180Details
BioGPS Gene Atlas220331_atUterus4.00067.180Details
BioGPS Gene Atlas220331_atUterusCorpus4.05067.180Details
BioGPS Gene Atlas220331_atWholeBlood4.85067.180Details
BioGPS Gene Atlas220331_atWholebrain819.20067.180Details
BioGPS Gene Atlas220331_atcolon4.60067.180Details
BioGPS Gene Atlas220331_atpineal_day8.80067.180Details
BioGPS Gene Atlas220331_atpineal_night9.52067.180Details
BioGPS Gene Atlas220331_atretina14.52567.180Details
BioGPS Gene Atlas220331_atsmall_intestine4.40067.180Details
BioGPS NCI60220331_at7864.3544.190Details
BioGPS NCI60220331_atA1723.9784.190Details
BioGPS NCI60220331_atA2044.1644.190Details
BioGPS NCI60220331_atA3614.2174.190Details
BioGPS NCI60220331_atA4984.1924.190Details
BioGPS NCI60220331_atA5494.2424.190Details
BioGPS NCI60220331_atACC34.4034.190Details
BioGPS NCI60220331_atACHN3.9784.190Details
BioGPS NCI60220331_atALVA314.3674.190Details
BioGPS NCI60220331_atCAKI14.3684.190Details
BioGPS NCI60220331_atCCRT CEM4.7104.190Details
BioGPS NCI60220331_atCOLO2054.1814.190Details
BioGPS NCI60220331_atDLD14.0734.190Details
BioGPS NCI60220331_atDU1454.0554.190Details
BioGPS NCI60220331_atEKVX4.0714.190Details
BioGPS NCI60220331_atGM1334.2664.190Details
BioGPS NCI60220331_atGM16004.3484.190Details
BioGPS NCI60220331_atGM23134.2464.190Details
BioGPS NCI60220331_atGM23454.2064.190Details
BioGPS NCI60220331_atGM24934.3214.190Details
BioGPS NCI60220331_atGM974.5534.190Details
BioGPS NCI60220331_atHCC29983.8004.190Details
BioGPS NCI60220331_atHCT1164.1654.190Details
BioGPS NCI60220331_atHCT153.9174.190Details
BioGPS NCI60220331_atHEK 293 T-rex4.4144.190Details
BioGPS NCI60220331_atHEK 293T4.1494.190Details
BioGPS NCI60220331_atHEK2934.1764.190Details
BioGPS NCI60220331_atHELA3.8864.190Details
BioGPS NCI60220331_atHEPG24.1524.190Details
BioGPS NCI60220331_atHL604.3014.190Details
BioGPS NCI60220331_atHOP624.1954.190Details
BioGPS NCI60220331_atHOP924.0124.190Details
BioGPS NCI60220331_atHS578T4.1314.190Details
BioGPS NCI60220331_atHSG4.0724.190Details
BioGPS NCI60220331_atHT10804.1494.190Details
BioGPS NCI60220331_atHT294.5164.190Details
BioGPS NCI60220331_atIGROV14.1134.190Details
BioGPS NCI60220331_atIOSE804.1414.190Details
BioGPS NCI60220331_atJURKAT4.1794.190Details
BioGPS NCI60220331_atK5624.5794.190Details
BioGPS NCI60220331_atKM124.3914.190Details
BioGPS NCI60220331_atLN183.9294.190Details
BioGPS NCI60220331_atLNCAP4.1914.190Details
BioGPS NCI60220331_atLOX IMVI4.1834.190Details
BioGPS NCI60220331_atM144.1304.190Details
BioGPS NCI60220331_atMALME 3M4.4724.190Details
BioGPS NCI60220331_atMCF74.0254.190Details
BioGPS NCI60220331_atMD MB2314.2104.190Details
BioGPS NCI60220331_atMDA MB4354.3804.190Details
BioGPS NCI60220331_atMOLT44.2734.190Details
BioGPS NCI60220331_atNCI 4604.3024.190Details
BioGPS NCI60220331_atNCI H2264.2904.190Details
BioGPS NCI60220331_atNCI H234.1654.190Details
BioGPS NCI60220331_atNCI H322M4.1864.190Details
BioGPS NCI60220331_atNCVADR RES4.0104.190Details
BioGPS NCI60220331_atOVCAR34.4034.190Details
BioGPS NCI60220331_atOVCAR44.1694.190Details
BioGPS NCI60220331_atOVCAR54.1504.190Details
BioGPS NCI60220331_atOVCAR83.9824.190Details
BioGPS NCI60220331_atPANC14.2264.190Details
BioGPS NCI60220331_atRL74.2644.190Details
BioGPS NCI60220331_atRPMI 82264.2914.190Details
BioGPS NCI60220331_atRS118464.4904.190Details
BioGPS NCI60220331_atRXF3934.1674.190Details
BioGPS NCI60220331_atSAOS24.2354.190Details
BioGPS NCI60220331_atSF2684.1814.190Details
BioGPS NCI60220331_atSF2954.1134.190Details
BioGPS NCI60220331_atSF5394.0074.190Details
BioGPS NCI60220331_atSHSYSY+RA4.0774.190Details
BioGPS NCI60220331_atSHSYSY-RA4.1404.190Details
BioGPS NCI60220331_atSKMEL24.1634.190Details
BioGPS NCI60220331_atSKMEL284.1924.190Details
BioGPS NCI60220331_atSKMEL54.0374.190Details
BioGPS NCI60220331_atSKOV34.3634.190Details
BioGPS NCI60220331_atSN12C4.1524.190Details
BioGPS NCI60220331_atSNB193.9654.190Details
BioGPS NCI60220331_atSNB754.1634.190Details
BioGPS NCI60220331_atSR4.2754.190Details
BioGPS NCI60220331_atSW6204.2454.190Details
BioGPS NCI60220331_atT244.3084.190Details
BioGPS NCI60220331_atT3M44.3204.190Details
BioGPS NCI60220331_atTK104.1744.190Details
BioGPS NCI60220331_atU1184.0694.190Details
BioGPS NCI60220331_atU1383.9344.190Details
BioGPS NCI60220331_atU20S4.0544.190Details
BioGPS NCI60220331_atU2514.1614.190Details
BioGPS NCI60220331_atU874.0604.190Details
BioGPS NCI60220331_atUACC2574.1354.190Details
BioGPS NCI60220331_atUACC624.2184.190Details
BioGPS NCI60220331_atUO314.0774.190Details
BioGPS NCI60220331_atZR75_14.2704.190Details
BioGPS NCI60220331_atastrocytes4.1914.190Details
BioGPS NCI60220331_athuh-74.2794.190Details