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Gene ID: 120227 | CYP2R1 Antibody Resource


CYP2R1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 2, subfamily R, polypeptide 1
Uniprot: 
Q6VVX0
Protein Name: 
vitamin D 25-hydroxylase
Nucleotide: 
XR_242777
Alias: 
Ensembl: 
ENSG00000186104
Location: 
11p15.2
HPRD: 
10569
NCBI Gene: 
120227
MIM: 
608713

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]
Function: 
Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D2 and D3.
Subcellular location: 
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
PTM: 
Disease: 
Rickets vitamin D-dependent 1B (VDDR1B) [MIM:600081]: A disorder caused by a selective deficiency of the active form of vitamin D (1,25-dihydroxyvitamin D3) and resulting in defective bone mineralization and clinical features of rickets. The patients sera have low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP49823_P050 CYP2R1 antibody - middle region (ARP49823_P050) Polyclonal Dog, Human, Mouse, Pig, Rabbit, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAAB04973 CYP2R1 antibody - C-terminal region (OAAB04973) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB04974 CYP2R1 antibody - center region (OAAB04974) Human; Mouse WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP49824_P050 CYP2R1 Antibody - C-terminal region (ARP49824_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody OAAF02954 CYP2R1 Antibody (OAAF02954) Polyclonal Human, Mouse IHC, WB, IF, ELISA 100 ug $229 Details

Show all CYP2R1 antibodies


Product Images
CYP2R1 antibody - middle region (ARP49823_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat

CYP2R1 Antibody - C-terminal region (ARP49824_P050) in Human COLO205 cells using Western Blot

Sample Type: Human COLO205

CYP2R1 antibody - C-terminal region (OAAB04973) in human brain cells using Immunohistochemistry

Sample Type: human brain

CYP2R1 antibody - C-terminal region (OAAB04973) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

CYP2R1 antibody - center region (OAAB04974) in human brain cells using Immunohistochemistry

Sample Type: human brain

CYP2R1 antibody - center region (OAAB04974) in NCI-H460 and mouse liver cells using Western Blot

Sample Type: NCI-H460 and mouse liver

CYP2R1 Antibody (OAAF02954) in HT-29 cells using Western Blot

Sample Type: HT-29

CYP2R1 Antibody (OAAF02954) in Human colon carcinoma cells using Immunohistochemistry

Sample Type: Human colon carcinoma


CYP2R1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP49823 Bovine CYP2R1 antibody; Bos taurus CYP2R1 antibody F1MFR3 100.0%
ARP49824 Bovine CYP2R1 antibody; Bos taurus CYP2R1 antibody Q0P5I1 93.0%
ARP49824 Bovine CYP2R1 antibody; Bos taurus CYP2R1 antibody F1MFR3 93.0%
ARP49823 Cat CYP2R1 antibody; Felis catus CYP2R1 antibody M3WF06 100.0%
ARP49824 Cat CYP2R1 antibody; Felis catus CYP2R1 antibody M3WF06 100.0%
ARP49823 Chicken CYP2R1 antibody; Gallus gallus CYP2R1 antibody F1NB14 93.0%
ARP49823 Chimpanzee CYP2R1 antibody; Pan troglodytes CYP2R1 antibody H2Q380 100.0%
ARP49824 Chimpanzee CYP2R1 antibody; Pan troglodytes CYP2R1 antibody H2Q380 100.0%
ARP49823 Chinese softshell turtle CYP2R1 antibody; Pelodiscus sinensis CYP2R1 antibody K7FYI4 93.0%
ARP49823 Collared flycatcher CYP2R1 antibody; Ficedula albicollis CYP2R1 antibody U3JDJ5 93.0%
ARP49823 Dog CYP2R1 antibody; Canis familiaris CYP2R1 antibody E2R3K2 100.0%
ARP49824 Dog CYP2R1 antibody; Canis familiaris CYP2R1 antibody E2R3K2 93.0%
ARP49823 Domestic duck CYP2R1 antibody; Anas platyrhynchos CYP2R1 antibody U3ILD4 93.0%
ARP49823 European domestic ferret CYP2R1 antibody; Mustela putorius furo CYP2R1 antibody M3YP95 100.0%
ARP49824 European domestic ferret CYP2R1 antibody; Mustela putorius furo CYP2R1 antibody M3YP95 92.0%
ARP49823 Giant panda CYP2R1 antibody; Ailuropoda melanoleuca CYP2R1 antibody G1L6X8 100.0%
ARP49824 Giant panda CYP2R1 antibody; Ailuropoda melanoleuca CYP2R1 antibody G1L6X8 93.0%
ARP49823 Gray short-tailed opossum CYP2R1 antibody; Monodelphis domestica CYP2R1 antibody F7FQQ9 86.0%
ARP49823 Green anole CYP2R1 antibody; Anolis carolinensis CYP2R1 antibody G1KMN7 93.0%
ARP49823 Horse CYP2R1 antibody; Equus caballus CYP2R1 antibody F7DCA3 100.0%
ARP49824 Horse CYP2R1 antibody; Equus caballus CYP2R1 antibody F7DCA3 93.0%
ARP49823 Human CYP2R1 antibody; Homo sapiens CYP2R1 antibody Q6VVX0 100.0%
ARP49824 Human CYP2R1 antibody; Homo sapiens CYP2R1 antibody Q6VVX0 100.0%
ARP49824 Human CYP2R1 antibody; Homo sapiens CYP2R1 antibody E9PJT9 100.0%
ARP49823 Indian medaka CYP2R1 antibody; Oryzias melastigma CYP2R1 antibody R9S3N5 79.0%
ARP49823 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody Q32MW1 100.0%
ARP49823 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody Q6VVW9 100.0%
ARP49823 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody F6RCB2 100.0%
ARP49824 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody Q32MW0 93.0%
ARP49824 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody Q32MW1 93.0%
ARP49824 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody Q6VVW9 93.0%
ARP49824 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody Q8BI68 93.0%
ARP49824 Mouse CYP2R1 antibody; Mus musculus CYP2R1 antibody D3YTX0 93.0%
ARP49823 Pig CYP2R1 antibody; Sus scrofa CYP2R1 antibody A7KZR1 100.0%
ARP49823 Pig CYP2R1 antibody; Sus scrofa CYP2R1 antibody F1S984 100.0%
ARP49824 Pig CYP2R1 antibody; Sus scrofa CYP2R1 antibody F1S984 85.0%
ARP49823 Rabbit CYP2R1 antibody; Oryctolagus cuniculus CYP2R1 antibody G1TV70 93.0%
ARP49824 Rabbit CYP2R1 antibody; Oryctolagus cuniculus CYP2R1 antibody G1TV70 93.0%
ARP49823 Rabbit CYP2R1 antibody; Oryctolagus cuniculus CYP2R1 antibody U3KNB1 93.0%
ARP49824 Rabbit CYP2R1 antibody; Oryctolagus cuniculus CYP2R1 antibody U3KNB1 93.0%
ARP49824 Rat CYP2R1 antibody; Rattus norvegicus CYP2R1 antibody F7FAJ1 93.0%
ARP49823 Rhesus macaque CYP2R1 antibody; Macaca mulatta CYP2R1 antibody H9F693 100.0%
ARP49824 Rhesus macaque CYP2R1 antibody; Macaca mulatta CYP2R1 antibody H9F693 100.0%
ARP49823 Rhesus macaque CYP2R1 antibody; Macaca mulatta CYP2R1 antibody F6RJZ8 100.0%
ARP49824 Rhesus macaque CYP2R1 antibody; Macaca mulatta CYP2R1 antibody F6RJZ8 100.0%
ARP49823 Rhesus macaque CYP2R1 antibody; Macaca mulatta CYP2R1 antibody F6XN90 100.0%
ARP49824 Rhesus macaque CYP2R1 antibody; Macaca mulatta CYP2R1 antibody F6XN90 100.0%
ARP49824 Rhesus macaque CYP2R1 antibody; Macaca mulatta CYP2R1 antibody F6XNB4 100.0%
ARP49823 Small-eared galago CYP2R1 antibody; Otolemur garnettii CYP2R1 antibody H0WTV3 93.0%
ARP49824 Small-eared galago CYP2R1 antibody; Otolemur garnettii CYP2R1 antibody H0WTV3 93.0%
ARP49823 Sumatran orangutan CYP2R1 antibody; Pongo abelii CYP2R1 antibody H2NE13 100.0%
ARP49824 Sumatran orangutan CYP2R1 antibody; Pongo abelii CYP2R1 antibody H2NE13 100.0%
ARP49823 Tasmanian devil CYP2R1 antibody; Sarcophilus harrisii CYP2R1 antibody G3WQ15 86.0%
ARP49823 Thirteen-lined ground squirrel CYP2R1 antibody; Spermophilus tridecemlineatus CYP2R1 antibody I3MRG8 100.0%
ARP49824 Thirteen-lined ground squirrel CYP2R1 antibody; Spermophilus tridecemlineatus CYP2R1 antibody I3MRG8 86.0%
ARP49823 White-tufted-ear marmoset CYP2R1 antibody; Callithrix jacchus CYP2R1 antibody F7I9Q1 100.0%
ARP49824 White-tufted-ear marmoset CYP2R1 antibody; Callithrix jacchus CYP2R1 antibody F7I9Q1 93.0%
ARP49823 Zebra finch CYP2R1 antibody; Taeniopygia guttata CYP2R1 antibody H0ZDU4 93.0%
ARP49823 Zebrafish CYP2R1 antibody; Danio rerio CYP2R1 antibody A9JRH5 79.0%
ARP49823 Zebrafish CYP2R1 antibody; Danio rerio CYP2R1 antibody F6P2A1 79.0%
ARP49823 Zebrafish CYP2R1 antibody; Danio rerio CYP2R1 antibody F8W4J4 79.0%
ARP49823 Zebrafish CYP2R1 antibody; Danio rerio CYP2R1 antibody F8W5N4 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207786_at721_B_lymphoblasts6.9005.930Details
BioGPS Gene Atlas207786_atAdipocyte5.8005.930Details
BioGPS Gene Atlas207786_atAdrenalCortex6.4505.930Details
BioGPS Gene Atlas207786_atAdrenalgland4.8505.930Details
BioGPS Gene Atlas207786_atAmygdala5.9005.930Details
BioGPS Gene Atlas207786_atAppendix6.3005.930Details
BioGPS Gene Atlas207786_atAtrioventricularNode5.3005.930Details
BioGPS Gene Atlas207786_atBDCA4+_DentriticCells6.5505.930Details
BioGPS Gene Atlas207786_atBonemarrow5.7005.930Details
BioGPS Gene Atlas207786_atBronchialEpithelialCells5.7505.930Details
BioGPS Gene Atlas207786_atCD105+_Endothelial5.8005.930Details
BioGPS Gene Atlas207786_atCD14+_Monocytes6.2505.930Details
BioGPS Gene Atlas207786_atCD19+_BCells(neg._sel.)6.2505.930Details
BioGPS Gene Atlas207786_atCD33+_Myeloid7.5505.930Details
BioGPS Gene Atlas207786_atCD34+7.4505.930Details
BioGPS Gene Atlas207786_atCD4+_Tcells6.4005.930Details
BioGPS Gene Atlas207786_atCD56+_NKCells7.5505.930Details
BioGPS Gene Atlas207786_atCD71+_EarlyErythroid5.4005.930Details
BioGPS Gene Atlas207786_atCD8+_Tcells5.7505.930Details
BioGPS Gene Atlas207786_atCardiacMyocytes8.7005.930Details
BioGPS Gene Atlas207786_atCaudatenucleus5.2005.930Details
BioGPS Gene Atlas207786_atCerebellum4.7005.930Details
BioGPS Gene Atlas207786_atCerebellumPeduncles6.9005.930Details
BioGPS Gene Atlas207786_atCiliaryGanglion4.7005.930Details
BioGPS Gene Atlas207786_atCingulateCortex5.9505.930Details
BioGPS Gene Atlas207786_atColorectaladenocarcinoma5.9005.930Details
BioGPS Gene Atlas207786_atDorsalRootGanglion4.7005.930Details
BioGPS Gene Atlas207786_atFetalThyroid5.7505.930Details
BioGPS Gene Atlas207786_atFetalbrain5.7005.930Details
BioGPS Gene Atlas207786_atFetalliver4.9505.930Details
BioGPS Gene Atlas207786_atFetallung4.4505.930Details
BioGPS Gene Atlas207786_atGlobusPallidus4.5005.930Details
BioGPS Gene Atlas207786_atHeart7.5005.930Details
BioGPS Gene Atlas207786_atHypothalamus6.1005.930Details
BioGPS Gene Atlas207786_atKidney4.6505.930Details
BioGPS Gene Atlas207786_atLeukemia_chronicMyelogenousK-5625.2005.930Details
BioGPS Gene Atlas207786_atLeukemia_promyelocytic-HL-605.1505.930Details
BioGPS Gene Atlas207786_atLeukemialymphoblastic(MOLT-4)4.6505.930Details
BioGPS Gene Atlas207786_atLiver7.9505.930Details
BioGPS Gene Atlas207786_atLung6.3005.930Details
BioGPS Gene Atlas207786_atLymphnode4.7505.930Details
BioGPS Gene Atlas207786_atLymphoma_burkitts(Daudi)7.6505.930Details
BioGPS Gene Atlas207786_atLymphoma_burkitts(Raji)8.5505.930Details
BioGPS Gene Atlas207786_atMedullaOblongata5.3505.930Details
BioGPS Gene Atlas207786_atOccipitalLobe5.2005.930Details
BioGPS Gene Atlas207786_atOlfactoryBulb4.6005.930Details
BioGPS Gene Atlas207786_atOvary4.1005.930Details
BioGPS Gene Atlas207786_atPancreas4.8005.930Details
BioGPS Gene Atlas207786_atPancreaticIslet6.3005.930Details
BioGPS Gene Atlas207786_atParietalLobe6.2005.930Details
BioGPS Gene Atlas207786_atPituitary6.7005.930Details
BioGPS Gene Atlas207786_atPlacenta5.7505.930Details
BioGPS Gene Atlas207786_atPons5.5505.930Details
BioGPS Gene Atlas207786_atPrefrontalCortex7.1005.930Details
BioGPS Gene Atlas207786_atProstate6.8005.930Details
BioGPS Gene Atlas207786_atSalivarygland4.7505.930Details
BioGPS Gene Atlas207786_atSkeletalMuscle7.3005.930Details
BioGPS Gene Atlas207786_atSkin4.7505.930Details
BioGPS Gene Atlas207786_atSmoothMuscle6.5505.930Details
BioGPS Gene Atlas207786_atSpinalcord6.2005.930Details
BioGPS Gene Atlas207786_atSubthalamicNucleus5.4505.930Details
BioGPS Gene Atlas207786_atSuperiorCervicalGanglion6.8505.930Details
BioGPS Gene Atlas207786_atTemporalLobe5.3505.930Details
BioGPS Gene Atlas207786_atTestis5.0005.930Details
BioGPS Gene Atlas207786_atTestisGermCell4.9505.930Details
BioGPS Gene Atlas207786_atTestisIntersitial4.9005.930Details
BioGPS Gene Atlas207786_atTestisLeydigCell5.8005.930Details
BioGPS Gene Atlas207786_atTestisSeminiferousTubule5.0005.930Details
BioGPS Gene Atlas207786_atThalamus5.9005.930Details
BioGPS Gene Atlas207786_atThymus4.4005.930Details
BioGPS Gene Atlas207786_atThyroid7.0505.930Details
BioGPS Gene Atlas207786_atTongue5.9005.930Details
BioGPS Gene Atlas207786_atTonsil5.7005.930Details
BioGPS Gene Atlas207786_atTrachea4.8005.930Details
BioGPS Gene Atlas207786_atTrigeminalGanglion6.5005.930Details
BioGPS Gene Atlas207786_atUterus4.7005.930Details
BioGPS Gene Atlas207786_atUterusCorpus5.5505.930Details
BioGPS Gene Atlas207786_atWholeBlood6.4505.930Details
BioGPS Gene Atlas207786_atWholebrain4.6005.930Details
BioGPS Gene Atlas207786_atcolon5.8005.930Details
BioGPS Gene Atlas207786_atpineal_day7.1205.930Details
BioGPS Gene Atlas207786_atpineal_night7.0205.930Details
BioGPS Gene Atlas207786_atretina7.0505.930Details
BioGPS Gene Atlas207786_atsmall_intestine5.6505.930Details
BioGPS NCI60207786_at7866.2586.080Details
BioGPS NCI60207786_atA1725.5216.080Details
BioGPS NCI60207786_atA2045.9666.080Details
BioGPS NCI60207786_atA3616.0406.080Details
BioGPS NCI60207786_atA4986.0036.080Details
BioGPS NCI60207786_atA5496.1126.080Details
BioGPS NCI60207786_atACC36.6976.080Details
BioGPS NCI60207786_atACHN5.7896.080Details
BioGPS NCI60207786_atALVA316.8886.080Details
BioGPS NCI60207786_atCAKI16.5016.080Details
BioGPS NCI60207786_atCCRT CEM7.9036.080Details
BioGPS NCI60207786_atCOLO2056.1466.080Details
BioGPS NCI60207786_atDLD15.8926.080Details
BioGPS NCI60207786_atDU1455.8456.080Details
BioGPS NCI60207786_atEKVX5.6096.080Details
BioGPS NCI60207786_atGM1336.2656.080Details
BioGPS NCI60207786_atGM16006.7496.080Details
BioGPS NCI60207786_atGM23136.3606.080Details
BioGPS NCI60207786_atGM23456.0286.080Details
BioGPS NCI60207786_atGM24936.7266.080Details
BioGPS NCI60207786_atGM976.4206.080Details
BioGPS NCI60207786_atHCC29985.1156.080Details
BioGPS NCI60207786_atHCT1166.0056.080Details
BioGPS NCI60207786_atHCT155.7846.080Details
BioGPS NCI60207786_atHEK 293 T-rex6.4126.080Details
BioGPS NCI60207786_atHEK 293T6.0826.080Details
BioGPS NCI60207786_atHEK2936.1106.080Details
BioGPS NCI60207786_atHELA5.4446.080Details
BioGPS NCI60207786_atHEPG26.0156.080Details
BioGPS NCI60207786_atHL606.3206.080Details
BioGPS NCI60207786_atHOP626.0406.080Details
BioGPS NCI60207786_atHOP925.9406.080Details
BioGPS NCI60207786_atHS578T5.8936.080Details
BioGPS NCI60207786_atHSG5.6246.080Details
BioGPS NCI60207786_atHT10805.8836.080Details
BioGPS NCI60207786_atHT296.9836.080Details
BioGPS NCI60207786_atIGROV15.9766.080Details
BioGPS NCI60207786_atIOSE805.9676.080Details
BioGPS NCI60207786_atJURKAT6.0246.080Details
BioGPS NCI60207786_atK5626.9216.080Details
BioGPS NCI60207786_atKM126.4786.080Details
BioGPS NCI60207786_atLN185.3566.080Details
BioGPS NCI60207786_atLNCAP6.0206.080Details
BioGPS NCI60207786_atLOX IMVI6.0156.080Details
BioGPS NCI60207786_atM145.9736.080Details
BioGPS NCI60207786_atMALME 3M6.7706.080Details
BioGPS NCI60207786_atMCF75.9106.080Details
BioGPS NCI60207786_atMD MB2316.1366.080Details
BioGPS NCI60207786_atMDA MB4356.9106.080Details
BioGPS NCI60207786_atMOLT46.5876.080Details
BioGPS NCI60207786_atNCI 4606.2656.080Details
BioGPS NCI60207786_atNCI H2266.3276.080Details
BioGPS NCI60207786_atNCI H236.0076.080Details
BioGPS NCI60207786_atNCI H322M6.0116.080Details
BioGPS NCI60207786_atNCVADR RES5.4426.080Details
BioGPS NCI60207786_atOVCAR36.6006.080Details
BioGPS NCI60207786_atOVCAR45.9526.080Details
BioGPS NCI60207786_atOVCAR55.8096.080Details
BioGPS NCI60207786_atOVCAR85.4506.080Details
BioGPS NCI60207786_atPANC16.0796.080Details
BioGPS NCI60207786_atRL76.2526.080Details
BioGPS NCI60207786_atRPMI 82266.3626.080Details
BioGPS NCI60207786_atRS118466.6346.080Details
BioGPS NCI60207786_atRXF3935.9846.080Details
BioGPS NCI60207786_atSAOS26.0946.080Details
BioGPS NCI60207786_atSF2685.9926.080Details
BioGPS NCI60207786_atSF2955.8836.080Details
BioGPS NCI60207786_atSF5395.8196.080Details
BioGPS NCI60207786_atSHSYSY+RA5.9126.080Details
BioGPS NCI60207786_atSHSYSY-RA5.9926.080Details
BioGPS NCI60207786_atSKMEL25.9966.080Details
BioGPS NCI60207786_atSKMEL286.0356.080Details
BioGPS NCI60207786_atSKMEL55.8966.080Details
BioGPS NCI60207786_atSKOV36.4596.080Details
BioGPS NCI60207786_atSN12C5.9966.080Details
BioGPS NCI60207786_atSNB195.4546.080Details
BioGPS NCI60207786_atSNB755.8986.080Details
BioGPS NCI60207786_atSR6.1056.080Details
BioGPS NCI60207786_atSW6206.2036.080Details
BioGPS NCI60207786_atT246.2076.080Details
BioGPS NCI60207786_atT3M46.4576.080Details
BioGPS NCI60207786_atTK105.9546.080Details
BioGPS NCI60207786_atU1185.7316.080Details
BioGPS NCI60207786_atU1385.4506.080Details
BioGPS NCI60207786_atU20S5.9876.080Details
BioGPS NCI60207786_atU2515.9406.080Details
BioGPS NCI60207786_atU875.6706.080Details
BioGPS NCI60207786_atUACC2575.7426.080Details
BioGPS NCI60207786_atUACC626.0766.080Details
BioGPS NCI60207786_atUO315.7116.080Details
BioGPS NCI60207786_atZR75_16.4026.080Details
BioGPS NCI60207786_atastrocytes6.0716.080Details
BioGPS NCI60207786_athuh-76.2796.080Details