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Gene ID: 1593 | CYP27A1 Antibody Resource


CYP27A1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 27, subfamily A, polypeptide 1
Uniprot: 
Q02318
Protein Name: 
sterol 26-hydroxylase, mitochondrial
Nucleotide: 
NM_000784
Alias: 
CTX;CP27;CYP27;
Ensembl: 
ENSG00000135929
Location: 
2q35
HPRD: 
05939
NCBI Gene: 
1593
MIM: 
606530

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008]
Function: 
Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Subcellular location: 
Mitochondrion membrane.
PTM: 
Acetylation;
Disease: 
Cerebrotendinous xanthomatosis (CTX) [MIM:213700]: Rare sterol storage disorder characterized clinically by progressive neurologic dysfunction, premature atherosclerosis, and cataracts. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP51773_P050 CYP27A1 antibody - middle region (ARP51773_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody OAAB01592 CYP27A1 antibody - N-terminal region (OAAB01592) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP51772_P050 CYP27A1 Antibody (ARP51772_P050) Polyclonal Guinea pig, Horse, Human, Mouse, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAF02944 CYP27A1 Antibody (OAAF02944) Polyclonal Human WB, ELISA 100 ug $289 Details

Show all CYP27A1 antibodies


Product Images
CYP27A1 antibody - middle region (ARP51773_P050) in Human Brain cells using Western Blot

Sample Type: Human Brain

CYP27A1 Antibody (OAAF02944) in HeLa cells using Western Blot

Sample Type: HeLa


CYP27A1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP51773 Cat CYP27A1 antibody; Felis catus CYP27A1 antibody M3W709 83.0%
ARP51772 Chimpanzee CYP27A1 antibody; Pan troglodytes CYP27A1 antibody H2QJF6 100.0%
ARP51773 Chimpanzee CYP27A1 antibody; Pan troglodytes CYP27A1 antibody H2QJF6 100.0%
ARP51772 Chimpanzee CYP27A1 antibody; Pan troglodytes CYP27A1 antibody K7CD19 100.0%
ARP51773 Chimpanzee CYP27A1 antibody; Pan troglodytes CYP27A1 antibody K7CD19 100.0%
ARP51772 Crab-eating macaque CYP27A1 antibody; Macaca fascicularis CYP27A1 antibody B8K1T2 100.0%
ARP51773 Crab-eating macaque CYP27A1 antibody; Macaca fascicularis CYP27A1 antibody B8K1T2 100.0%
ARP51772 Crab-eating macaque CYP27A1 antibody; Macaca fascicularis CYP27A1 antibody Q60HG5 100.0%
ARP51772 Horse CYP27A1 antibody; Equus caballus CYP27A1 antibody F7DXD2 86.0%
ARP51772 Human CYP27A1 antibody; Homo sapiens CYP27A1 antibody C9J1K5 100.0%
ARP51772 Human CYP27A1 antibody; Homo sapiens CYP27A1 antibody Q02318 100.0%
ARP51773 Human CYP27A1 antibody; Homo sapiens CYP27A1 antibody Q02318 100.0%
ARP51772 Mouse CYP27A1 antibody; Mus musculus CYP27A1 antibody Q99LX3 79.0%
ARP51772 Mouse CYP27A1 antibody; Mus musculus CYP27A1 antibody Q9DBG1 79.0%
ARP51772 Rabbit CYP27A1 antibody; Oryctolagus cuniculus CYP27A1 antibody P17177 93.0%
ARP51772 Rat CYP27A1 antibody; Rattus norvegicus CYP27A1 antibody P17178 79.0%
ARP51772 Rhesus macaque CYP27A1 antibody; Macaca mulatta CYP27A1 antibody F7HD06 100.0%
ARP51773 Rhesus macaque CYP27A1 antibody; Macaca mulatta CYP27A1 antibody F7HD06 93.0%
ARP51773 Small-eared galago CYP27A1 antibody; Otolemur garnettii CYP27A1 antibody H0WPE1 79.0%
ARP51772 Thirteen-lined ground squirrel CYP27A1 antibody; Spermophilus tridecemlineatus CYP27A1 antibody I3M880 79.0%
ARP51772 White-tufted-ear marmoset CYP27A1 antibody; Callithrix jacchus CYP27A1 antibody F7CZ63 100.0%
ARP51772 White-tufted-ear marmoset CYP27A1 antibody; Callithrix jacchus CYP27A1 antibody F7DY05 100.0%
ARP51772 White-tufted-ear marmoset CYP27A1 antibody; Callithrix jacchus CYP27A1 antibody U3AV03 100.0%
ARP51773 White-tufted-ear marmoset CYP27A1 antibody; Callithrix jacchus CYP27A1 antibody F7CZ63 86.0%
ARP51773 White-tufted-ear marmoset CYP27A1 antibody; Callithrix jacchus CYP27A1 antibody F7DY05 86.0%
ARP51773 White-tufted-ear marmoset CYP27A1 antibody; Callithrix jacchus CYP27A1 antibody U3AV03 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas203979_at721_B_lymphoblasts23.45052.340Details
BioGPS Gene Atlas203979_atAdipocyte19.25052.340Details
BioGPS Gene Atlas203979_atAdrenalCortex21.10052.340Details
BioGPS Gene Atlas203979_atAdrenalgland20.75052.340Details
BioGPS Gene Atlas203979_atAmygdala18.40052.340Details
BioGPS Gene Atlas203979_atAppendix21.65052.340Details
BioGPS Gene Atlas203979_atAtrioventricularNode17.80052.340Details
BioGPS Gene Atlas203979_atBDCA4+_DentriticCells20.65052.340Details
BioGPS Gene Atlas203979_atBonemarrow20.00052.340Details
BioGPS Gene Atlas203979_atBronchialEpithelialCells19.35052.340Details
BioGPS Gene Atlas203979_atCD105+_Endothelial20.55052.340Details
BioGPS Gene Atlas203979_atCD14+_Monocytes221.45052.340Details
BioGPS Gene Atlas203979_atCD19+_BCells(neg._sel.)20.70052.340Details
BioGPS Gene Atlas203979_atCD33+_Myeloid106.10052.340Details
BioGPS Gene Atlas203979_atCD34+24.75052.340Details
BioGPS Gene Atlas203979_atCD4+_Tcells20.30052.340Details
BioGPS Gene Atlas203979_atCD56+_NKCells22.15052.340Details
BioGPS Gene Atlas203979_atCD71+_EarlyErythroid18.70052.340Details
BioGPS Gene Atlas203979_atCD8+_Tcells18.45052.340Details
BioGPS Gene Atlas203979_atCardiacMyocytes25.20052.340Details
BioGPS Gene Atlas203979_atCaudatenucleus18.10052.340Details
BioGPS Gene Atlas203979_atCerebellum16.25052.340Details
BioGPS Gene Atlas203979_atCerebellumPeduncles22.80052.340Details
BioGPS Gene Atlas203979_atCiliaryGanglion15.05052.340Details
BioGPS Gene Atlas203979_atCingulateCortex20.15052.340Details
BioGPS Gene Atlas203979_atColorectaladenocarcinoma20.15052.340Details
BioGPS Gene Atlas203979_atDorsalRootGanglion15.35052.340Details
BioGPS Gene Atlas203979_atFetalThyroid19.45052.340Details
BioGPS Gene Atlas203979_atFetalbrain19.70052.340Details
BioGPS Gene Atlas203979_atFetalliver27.30052.340Details
BioGPS Gene Atlas203979_atFetallung22.65052.340Details
BioGPS Gene Atlas203979_atGlobusPallidus14.40052.340Details
BioGPS Gene Atlas203979_atHeart28.90052.340Details
BioGPS Gene Atlas203979_atHypothalamus23.40052.340Details
BioGPS Gene Atlas203979_atKidney25.15052.340Details
BioGPS Gene Atlas203979_atLeukemia_chronicMyelogenousK-56218.15052.340Details
BioGPS Gene Atlas203979_atLeukemia_promyelocytic-HL-6017.25052.340Details
BioGPS Gene Atlas203979_atLeukemialymphoblastic(MOLT-4)16.10052.340Details
BioGPS Gene Atlas203979_atLiver2039.25052.340Details
BioGPS Gene Atlas203979_atLung300.85052.340Details
BioGPS Gene Atlas203979_atLymphnode30.50052.340Details
BioGPS Gene Atlas203979_atLymphoma_burkitts(Daudi)25.95052.340Details
BioGPS Gene Atlas203979_atLymphoma_burkitts(Raji)28.55052.340Details
BioGPS Gene Atlas203979_atMedullaOblongata18.05052.340Details
BioGPS Gene Atlas203979_atOccipitalLobe17.60052.340Details
BioGPS Gene Atlas203979_atOlfactoryBulb23.30052.340Details
BioGPS Gene Atlas203979_atOvary21.20052.340Details
BioGPS Gene Atlas203979_atPancreas16.30052.340Details
BioGPS Gene Atlas203979_atPancreaticIslet24.55052.340Details
BioGPS Gene Atlas203979_atParietalLobe21.25052.340Details
BioGPS Gene Atlas203979_atPituitary27.60052.340Details
BioGPS Gene Atlas203979_atPlacenta16.55052.340Details
BioGPS Gene Atlas203979_atPons18.75052.340Details
BioGPS Gene Atlas203979_atPrefrontalCortex23.80052.340Details
BioGPS Gene Atlas203979_atProstate35.20052.340Details
BioGPS Gene Atlas203979_atSalivarygland22.50052.340Details
BioGPS Gene Atlas203979_atSkeletalMuscle22.80052.340Details
BioGPS Gene Atlas203979_atSkin17.05052.340Details
BioGPS Gene Atlas203979_atSmoothMuscle22.70052.340Details
BioGPS Gene Atlas203979_atSpinalcord29.00052.340Details
BioGPS Gene Atlas203979_atSubthalamicNucleus14.65052.340Details
BioGPS Gene Atlas203979_atSuperiorCervicalGanglion23.30052.340Details
BioGPS Gene Atlas203979_atTemporalLobe18.10052.340Details
BioGPS Gene Atlas203979_atTestis17.20052.340Details
BioGPS Gene Atlas203979_atTestisGermCell15.75052.340Details
BioGPS Gene Atlas203979_atTestisIntersitial16.45052.340Details
BioGPS Gene Atlas203979_atTestisLeydigCell19.90052.340Details
BioGPS Gene Atlas203979_atTestisSeminiferousTubule17.30052.340Details
BioGPS Gene Atlas203979_atThalamus24.45052.340Details
BioGPS Gene Atlas203979_atThymus15.95052.340Details
BioGPS Gene Atlas203979_atThyroid22.05052.340Details
BioGPS Gene Atlas203979_atTongue19.35052.340Details
BioGPS Gene Atlas203979_atTonsil20.55052.340Details
BioGPS Gene Atlas203979_atTrachea16.75052.340Details
BioGPS Gene Atlas203979_atTrigeminalGanglion24.65052.340Details
BioGPS Gene Atlas203979_atUterus16.45052.340Details
BioGPS Gene Atlas203979_atUterusCorpus18.90052.340Details
BioGPS Gene Atlas203979_atWholeBlood37.20052.340Details
BioGPS Gene Atlas203979_atWholebrain18.75052.340Details
BioGPS Gene Atlas203979_atcolon16.00052.340Details
BioGPS Gene Atlas203979_atpineal_day46.66052.340Details
BioGPS Gene Atlas203979_atpineal_night34.86052.340Details
BioGPS Gene Atlas203979_atretina61.12552.340Details
BioGPS Gene Atlas203979_atsmall_intestine21.80052.340Details
BioGPS NCI60203979_at78610.22157.520Details
BioGPS NCI60203979_atA1729.63357.520Details
BioGPS NCI60203979_atA20418.57757.520Details
BioGPS NCI60203979_atA36178.52557.520Details
BioGPS NCI60203979_atA49810.11057.520Details
BioGPS NCI60203979_atA54910.25057.520Details
BioGPS NCI60203979_atACC310.36957.520Details
BioGPS NCI60203979_atACHN10.50557.520Details
BioGPS NCI60203979_atALVA3110.38457.520Details
BioGPS NCI60203979_atCAKI110.57957.520Details
BioGPS NCI60203979_atCCRT CEM10.59057.520Details
BioGPS NCI60203979_atCOLO205583.22757.520Details
BioGPS NCI60203979_atDLD19.91957.520Details
BioGPS NCI60203979_atDU1459.79557.520Details
BioGPS NCI60203979_atEKVX5.89357.520Details
BioGPS NCI60203979_atGM13316.72957.520Details
BioGPS NCI60203979_atGM160010.63157.520Details
BioGPS NCI60203979_atGM231310.29557.520Details
BioGPS NCI60203979_atGM234510.53157.520Details
BioGPS NCI60203979_atGM249310.72757.520Details
BioGPS NCI60203979_atGM9710.71857.520Details
BioGPS NCI60203979_atHCC29986.48057.520Details
BioGPS NCI60203979_atHCT11612.68557.520Details
BioGPS NCI60203979_atHCT159.59157.520Details
BioGPS NCI60203979_atHEK 293 T-rex17.01157.520Details
BioGPS NCI60203979_atHEK 293T10.20457.520Details
BioGPS NCI60203979_atHEK29310.12557.520Details
BioGPS NCI60203979_atHELA9.51957.520Details
BioGPS NCI60203979_atHEPG2516.38257.520Details
BioGPS NCI60203979_atHL6010.71157.520Details
BioGPS NCI60203979_atHOP6210.19357.520Details
BioGPS NCI60203979_atHOP9216.47857.520Details
BioGPS NCI60203979_atHS578T9.94557.520Details
BioGPS NCI60203979_atHSG9.74557.520Details
BioGPS NCI60203979_atHT108010.06057.520Details
BioGPS NCI60203979_atHT2910.48657.520Details
BioGPS NCI60203979_atIGROV110.00757.520Details
BioGPS NCI60203979_atIOSE8010.08357.520Details
BioGPS NCI60203979_atJURKAT10.83957.520Details
BioGPS NCI60203979_atK56210.40657.520Details
BioGPS NCI60203979_atKM1210.23757.520Details
BioGPS NCI60203979_atLN188.28657.520Details
BioGPS NCI60203979_atLNCAP10.01957.520Details
BioGPS NCI60203979_atLOX IMVI10.13257.520Details
BioGPS NCI60203979_atM14252.04357.520Details
BioGPS NCI60203979_atMALME 3M116.81257.520Details
BioGPS NCI60203979_atMCF79.79257.520Details
BioGPS NCI60203979_atMD MB23115.21857.520Details
BioGPS NCI60203979_atMDA MB435585.92057.520Details
BioGPS NCI60203979_atMOLT410.17657.520Details
BioGPS NCI60203979_atNCI 46010.26657.520Details
BioGPS NCI60203979_atNCI H22610.23557.520Details
BioGPS NCI60203979_atNCI H2310.81657.520Details
BioGPS NCI60203979_atNCI H322M10.13357.520Details
BioGPS NCI60203979_atNCVADR RES7.24257.520Details
BioGPS NCI60203979_atOVCAR310.36857.520Details
BioGPS NCI60203979_atOVCAR410.05357.520Details
BioGPS NCI60203979_atOVCAR59.98657.520Details
BioGPS NCI60203979_atOVCAR86.73757.520Details
BioGPS NCI60203979_atPANC110.06857.520Details
BioGPS NCI60203979_atRL710.32657.520Details
BioGPS NCI60203979_atRPMI 822610.11257.520Details
BioGPS NCI60203979_atRS1184610.34157.520Details
BioGPS NCI60203979_atRXF39310.04957.520Details
BioGPS NCI60203979_atSAOS210.21157.520Details
BioGPS NCI60203979_atSF26810.24657.520Details
BioGPS NCI60203979_atSF2959.91857.520Details
BioGPS NCI60203979_atSF5399.74157.520Details
BioGPS NCI60203979_atSHSYSY+RA9.88957.520Details
BioGPS NCI60203979_atSHSYSY-RA8.98557.520Details
BioGPS NCI60203979_atSKMEL250.84657.520Details
BioGPS NCI60203979_atSKMEL28355.62257.520Details
BioGPS NCI60203979_atSKMEL5325.39057.520Details
BioGPS NCI60203979_atSKOV310.24657.520Details
BioGPS NCI60203979_atSN12C10.02257.520Details
BioGPS NCI60203979_atSNB1929.26457.520Details
BioGPS NCI60203979_atSNB7510.06257.520Details
BioGPS NCI60203979_atSR10.26757.520Details
BioGPS NCI60203979_atSW62014.79357.520Details
BioGPS NCI60203979_atT2410.24257.520Details
BioGPS NCI60203979_atT3M410.23257.520Details
BioGPS NCI60203979_atTK1010.03357.520Details
BioGPS NCI60203979_atU11810.00857.520Details
BioGPS NCI60203979_atU1389.52857.520Details
BioGPS NCI60203979_atU20S9.98957.520Details
BioGPS NCI60203979_atU25110.00357.520Details
BioGPS NCI60203979_atU879.97057.520Details
BioGPS NCI60203979_atUACC257612.43657.520Details
BioGPS NCI60203979_atUACC621668.46057.520Details
BioGPS NCI60203979_atUO319.79057.520Details
BioGPS NCI60203979_atZR75_110.43357.520Details
BioGPS NCI60203979_atastrocytes10.20457.520Details
BioGPS NCI60203979_athuh-725.82257.520Details