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Gene ID: 1591 | CYP24A1 Antibody Resource


CYP24A1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 24, subfamily A, polypeptide 1
Uniprot: 
Q07973
Protein Name: 
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
Nucleotide: 
XM_005260305
Alias: 
CP24;HCAI;CYP24;P450-CC24;
Ensembl: 
ENSG00000019186
Location: 
20q13
HPRD: 
00522
NCBI Gene: 
1591
MIM: 
126065

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function: 
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Subcellular location: 
Mitochondrion.
PTM: 
Disease: 
Hypercalcemia infantile (HCAI) [MIM:143880]: A disorder characterized by abnormally high level of calcium in the blood, failure to thrive, vomiting, dehydration, and nephrocalcinosis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP60146_P050 CYP24A1 antibody - C-terminal region (ARP60146_P050) Polyclonal Dog, Human, Mouse, Pig WB 50ug $289 Details
Polyclonal Antibody ARP60147_P050 CYP24A1 antibody - C-terminal region (ARP60147_P050) Polyclonal Bovine, Dog, Human, Mouse, Pig WB 50ug $289 Details
Polyclonal Antibody OAEB01016 CYP24A1 Antibody (OAEB01016) Human WB 0.1mg $289 Details
Polyclonal Antibody OAAB05242 CYP24A1 antibody - C-terminal region (OAAB05242) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody OAGA00442 CYP24A1 antibody (OAGA00442) Polyclonal Human, Mouse IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details
Polyclonal Antibody OAAF02941 CYP24A1 Antibody (OAAF02941) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all CYP24A1 antibodies


Product Images
CYP24A1 antibody - C-terminal region (ARP60146_P050) in Human MCF-7 cells using Western Blot

Sample Type: Human MCF-7

CYP24A1 antibody - C-terminal region (ARP60147_P050) in Human MDA-MB-435S cells using Western Blot

Sample Type: Human MDA-MB-435S

CYP24A1 antibody - C-terminal region (OAAB05242) in human spleen cells using Immunohistochemistry

Sample Type: human spleen

CYP24A1 antibody - C-terminal region (OAAB05242) in mouse spleen cells using Western Blot

Sample Type: mouse spleen

CYP24A1 Antibody (OAAF02941) in HUVEC cells using Western Blot

Sample Type: HUVEC

CYP24A1 Antibody (OAEB01016) in Human Liver cells using Western Blot

Sample Type: Human Liver


CYP24A1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60147 Bovine CYP24A1 antibody; Bos taurus CYP24A1 antibody E1BKM8 86.0%
ARP60146 Cat CYP24A1 antibody; Felis catus CYP24A1 antibody M3VYI6 79.0%
ARP60147 Cat CYP24A1 antibody; Felis catus CYP24A1 antibody M3VYI6 79.0%
ARP60147 Chimpanzee CYP24A1 antibody; Pan troglodytes CYP24A1 antibody H2R8V0 100.0%
ARP60147 Chinese softshell turtle CYP24A1 antibody; Pelodiscus sinensis CYP24A1 antibody K7GD85 79.0%
ARP60147 Chinese softshell turtle CYP24A1 antibody; Pelodiscus sinensis CYP24A1 antibody K7GD90 79.0%
ARP60147 Dog CYP24A1 antibody; Canis familiaris CYP24A1 antibody E2QZL2 86.0%
ARP60146 Dog CYP24A1 antibody; Canis familiaris CYP24A1 antibody E2QZL2 79.0%
ARP60147 European domestic ferret CYP24A1 antibody; Mustela putorius furo CYP24A1 antibody M3Y465 86.0%
ARP60146 European domestic ferret CYP24A1 antibody; Mustela putorius furo CYP24A1 antibody M3Y465 79.0%
ARP60147 Giant panda CYP24A1 antibody; Ailuropoda melanoleuca CYP24A1 antibody G1M3K6 79.0%
ARP60147 Horse CYP24A1 antibody; Equus caballus CYP24A1 antibody F6YIY6 86.0%
ARP60147 Human CYP24A1 antibody; Homo sapiens CYP24A1 antibody Q07973-2 100.0%
ARP60146 Human CYP24A1 antibody; Homo sapiens CYP24A1 antibody Q07973-3 100.0%
ARP60147 Human CYP24A1 antibody; Homo sapiens CYP24A1 antibody Q07973-3 100.0%
ARP60146 Human CYP24A1 antibody; Homo sapiens CYP24A1 antibody Q07973 100.0%
ARP60147 Human CYP24A1 antibody; Homo sapiens CYP24A1 antibody Q07973 100.0%
ARP60147 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TP55 86.0%
ARP60147 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TWW0 86.0%
ARP60147 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TWZ8 86.0%
ARP60147 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q64441 86.0%
ARP60146 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TP55 79.0%
ARP60146 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TWW0 79.0%
ARP60146 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TWZ8 79.0%
ARP60146 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TXU0 79.0%
ARP60147 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q3TXU0 79.0%
ARP60146 Mouse CYP24A1 antibody; Mus musculus CYP24A1 antibody Q64441 79.0%
ARP60147 Pig CYP24A1 antibody; Sus scrofa CYP24A1 antibody A5GFV8 86.0%
ARP60146 Pig CYP24A1 antibody; Sus scrofa CYP24A1 antibody A5GFV8 79.0%
ARP60147 Rabbit CYP24A1 antibody; Oryctolagus cuniculus CYP24A1 antibody G1SMU5 100.0%
ARP60146 Rabbit CYP24A1 antibody; Oryctolagus cuniculus CYP24A1 antibody G1SMU5 93.0%
ARP60146 Rat CYP24A1 antibody; Rattus norvegicus CYP24A1 antibody Q09128 86.0%
ARP60147 Rat CYP24A1 antibody; Rattus norvegicus CYP24A1 antibody Q09128 79.0%
ARP60146 Small-eared galago CYP24A1 antibody; Otolemur garnettii CYP24A1 antibody H0XF79 100.0%
ARP60147 Small-eared galago CYP24A1 antibody; Otolemur garnettii CYP24A1 antibody H0XF79 93.0%
ARP60146 Sumatran orangutan CYP24A1 antibody; Pongo abelii CYP24A1 antibody H2P2C1 100.0%
ARP60147 Sumatran orangutan CYP24A1 antibody; Pongo abelii CYP24A1 antibody H2P2C1 93.0%
ARP60147 Sumatran orangutan CYP24A1 antibody; Pongo abelii CYP24A1 antibody K7EW31 93.0%
ARP60146 Thirteen-lined ground squirrel CYP24A1 antibody; Spermophilus tridecemlineatus CYP24A1 antibody I3LZJ0 93.0%
ARP60147 Thirteen-lined ground squirrel CYP24A1 antibody; Spermophilus tridecemlineatus CYP24A1 antibody I3LZJ0 93.0%
ARP60146 White-tufted-ear marmoset CYP24A1 antibody; Callithrix jacchus CYP24A1 antibody F6ZJJ5 100.0%
ARP60147 White-tufted-ear marmoset CYP24A1 antibody; Callithrix jacchus CYP24A1 antibody F6ZJJ5 79.0%
ARP60147 White-tufted-ear marmoset CYP24A1 antibody; Callithrix jacchus CYP24A1 antibody F6ZJK8 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206504_at721_B_lymphoblasts9.1508.630Details
BioGPS Gene Atlas206504_atAdipocyte7.5008.630Details
BioGPS Gene Atlas206504_atAdrenalCortex10.1508.630Details
BioGPS Gene Atlas206504_atAdrenalgland7.1508.630Details
BioGPS Gene Atlas206504_atAmygdala7.7008.630Details
BioGPS Gene Atlas206504_atAppendix18.7508.630Details
BioGPS Gene Atlas206504_atAtrioventricularNode8.8508.630Details
BioGPS Gene Atlas206504_atBDCA4+_DentriticCells7.5508.630Details
BioGPS Gene Atlas206504_atBonemarrow8.4508.630Details
BioGPS Gene Atlas206504_atBronchialEpithelialCells7.6508.630Details
BioGPS Gene Atlas206504_atCD105+_Endothelial7.8508.630Details
BioGPS Gene Atlas206504_atCD14+_Monocytes9.8508.630Details
BioGPS Gene Atlas206504_atCD19+_BCells(neg._sel.)7.9508.630Details
BioGPS Gene Atlas206504_atCD33+_Myeloid9.5508.630Details
BioGPS Gene Atlas206504_atCD34+9.4008.630Details
BioGPS Gene Atlas206504_atCD4+_Tcells8.1008.630Details
BioGPS Gene Atlas206504_atCD56+_NKCells8.9008.630Details
BioGPS Gene Atlas206504_atCD71+_EarlyErythroid7.7008.630Details
BioGPS Gene Atlas206504_atCD8+_Tcells6.6008.630Details
BioGPS Gene Atlas206504_atCardiacMyocytes15.4508.630Details
BioGPS Gene Atlas206504_atCaudatenucleus7.0508.630Details
BioGPS Gene Atlas206504_atCerebellum6.2508.630Details
BioGPS Gene Atlas206504_atCerebellumPeduncles9.7008.630Details
BioGPS Gene Atlas206504_atCiliaryGanglion8.2508.630Details
BioGPS Gene Atlas206504_atCingulateCortex8.5008.630Details
BioGPS Gene Atlas206504_atColorectaladenocarcinoma21.0508.630Details
BioGPS Gene Atlas206504_atDorsalRootGanglion8.2008.630Details
BioGPS Gene Atlas206504_atFetalThyroid7.7508.630Details
BioGPS Gene Atlas206504_atFetalbrain7.2008.630Details
BioGPS Gene Atlas206504_atFetalliver7.0008.630Details
BioGPS Gene Atlas206504_atFetallung5.6008.630Details
BioGPS Gene Atlas206504_atGlobusPallidus8.3008.630Details
BioGPS Gene Atlas206504_atHeart14.0508.630Details
BioGPS Gene Atlas206504_atHypothalamus7.9508.630Details
BioGPS Gene Atlas206504_atKidney8.6008.630Details
BioGPS Gene Atlas206504_atLeukemia_chronicMyelogenousK-5626.8508.630Details
BioGPS Gene Atlas206504_atLeukemia_promyelocytic-HL-606.8008.630Details
BioGPS Gene Atlas206504_atLeukemialymphoblastic(MOLT-4)5.6008.630Details
BioGPS Gene Atlas206504_atLiver11.7508.630Details
BioGPS Gene Atlas206504_atLung8.1008.630Details
BioGPS Gene Atlas206504_atLymphnode6.0008.630Details
BioGPS Gene Atlas206504_atLymphoma_burkitts(Daudi)10.3008.630Details
BioGPS Gene Atlas206504_atLymphoma_burkitts(Raji)12.8008.630Details
BioGPS Gene Atlas206504_atMedullaOblongata7.9008.630Details
BioGPS Gene Atlas206504_atOccipitalLobe6.9508.630Details
BioGPS Gene Atlas206504_atOlfactoryBulb5.9008.630Details
BioGPS Gene Atlas206504_atOvary5.9008.630Details
BioGPS Gene Atlas206504_atPancreas6.6508.630Details
BioGPS Gene Atlas206504_atPancreaticIslet8.2008.630Details
BioGPS Gene Atlas206504_atParietalLobe9.3008.630Details
BioGPS Gene Atlas206504_atPituitary9.0508.630Details
BioGPS Gene Atlas206504_atPlacenta7.2508.630Details
BioGPS Gene Atlas206504_atPons10.2008.630Details
BioGPS Gene Atlas206504_atPrefrontalCortex9.0008.630Details
BioGPS Gene Atlas206504_atProstate8.6008.630Details
BioGPS Gene Atlas206504_atSalivarygland6.9508.630Details
BioGPS Gene Atlas206504_atSkeletalMuscle14.3008.630Details
BioGPS Gene Atlas206504_atSkin9.6008.630Details
BioGPS Gene Atlas206504_atSmoothMuscle8.7508.630Details
BioGPS Gene Atlas206504_atSpinalcord8.0508.630Details
BioGPS Gene Atlas206504_atSubthalamicNucleus7.4508.630Details
BioGPS Gene Atlas206504_atSuperiorCervicalGanglion12.5008.630Details
BioGPS Gene Atlas206504_atTemporalLobe7.2508.630Details
BioGPS Gene Atlas206504_atTestis6.4508.630Details
BioGPS Gene Atlas206504_atTestisGermCell6.3008.630Details
BioGPS Gene Atlas206504_atTestisIntersitial6.8008.630Details
BioGPS Gene Atlas206504_atTestisLeydigCell8.0008.630Details
BioGPS Gene Atlas206504_atTestisSeminiferousTubule6.6008.630Details
BioGPS Gene Atlas206504_atThalamus8.1508.630Details
BioGPS Gene Atlas206504_atThymus5.8008.630Details
BioGPS Gene Atlas206504_atThyroid9.0508.630Details
BioGPS Gene Atlas206504_atTongue9.2008.630Details
BioGPS Gene Atlas206504_atTonsil8.6008.630Details
BioGPS Gene Atlas206504_atTrachea6.5008.630Details
BioGPS Gene Atlas206504_atTrigeminalGanglion10.5508.630Details
BioGPS Gene Atlas206504_atUterus5.8508.630Details
BioGPS Gene Atlas206504_atUterusCorpus8.1008.630Details
BioGPS Gene Atlas206504_atWholeBlood8.2008.630Details
BioGPS Gene Atlas206504_atWholebrain5.9508.630Details
BioGPS Gene Atlas206504_atcolon7.6008.630Details
BioGPS Gene Atlas206504_atpineal_day9.5808.630Details
BioGPS Gene Atlas206504_atpineal_night9.6608.630Details
BioGPS Gene Atlas206504_atretina9.6258.630Details
BioGPS Gene Atlas206504_atsmall_intestine7.1508.630Details
BioGPS NCI60206504_at7869.283102.550Details
BioGPS NCI60206504_atA1727.001102.550Details
BioGPS NCI60206504_atA204435.712102.550Details
BioGPS NCI60206504_atA3618.750102.550Details
BioGPS NCI60206504_atA4988.252102.550Details
BioGPS NCI60206504_atA5491739.057102.550Details
BioGPS NCI60206504_atACC310.650102.550Details
BioGPS NCI60206504_atACHN7.027102.550Details
BioGPS NCI60206504_atALVA3112.280102.550Details
BioGPS NCI60206504_atCAKI110.708102.550Details
BioGPS NCI60206504_atCCRT CEM22.230102.550Details
BioGPS NCI60206504_atCOLO20517.688102.550Details
BioGPS NCI60206504_atDLD18.050102.550Details
BioGPS NCI60206504_atDU14526.576102.550Details
BioGPS NCI60206504_atEKVX2832.210102.550Details
BioGPS NCI60206504_atGM1338.854102.550Details
BioGPS NCI60206504_atGM16009.089102.550Details
BioGPS NCI60206504_atGM231310.922102.550Details
BioGPS NCI60206504_atGM23458.055102.550Details
BioGPS NCI60206504_atGM24939.961102.550Details
BioGPS NCI60206504_atGM9724.144102.550Details
BioGPS NCI60206504_atHCC29986.260102.550Details
BioGPS NCI60206504_atHCT116511.089102.550Details
BioGPS NCI60206504_atHCT156.819102.550Details
BioGPS NCI60206504_atHEK 293 T-rex9.520102.550Details
BioGPS NCI60206504_atHEK 293T7.982102.550Details
BioGPS NCI60206504_atHEK2938.213102.550Details
BioGPS NCI60206504_atHELA6.825102.550Details
BioGPS NCI60206504_atHEPG228.030102.550Details
BioGPS NCI60206504_atHL609.717102.550Details
BioGPS NCI60206504_atHOP628.281102.550Details
BioGPS NCI60206504_atHOP927.290102.550Details
BioGPS NCI60206504_atHS578T7.824102.550Details
BioGPS NCI60206504_atHSG7.851102.550Details
BioGPS NCI60206504_atHT10807.735102.550Details
BioGPS NCI60206504_atHT2913.518102.550Details
BioGPS NCI60206504_atIGROV18.030102.550Details
BioGPS NCI60206504_atIOSE809.056102.550Details
BioGPS NCI60206504_atJURKAT8.276102.550Details
BioGPS NCI60206504_atK56213.323102.550Details
BioGPS NCI60206504_atKM129.263102.550Details
BioGPS NCI60206504_atLN186.734102.550Details
BioGPS NCI60206504_atLNCAP8.377102.550Details
BioGPS NCI60206504_atLOX IMVI17.158102.550Details
BioGPS NCI60206504_atM148.210102.550Details
BioGPS NCI60206504_atMALME 3M11.309102.550Details
BioGPS NCI60206504_atMCF77.958102.550Details
BioGPS NCI60206504_atMD MB2319.196102.550Details
BioGPS NCI60206504_atMDA MB43510.726102.550Details
BioGPS NCI60206504_atMOLT49.015102.550Details
BioGPS NCI60206504_atNCI 4609.086102.550Details
BioGPS NCI60206504_atNCI H22611.043102.550Details
BioGPS NCI60206504_atNCI H23213.917102.550Details
BioGPS NCI60206504_atNCI H322M8.607102.550Details
BioGPS NCI60206504_atNCVADR RES6.741102.550Details
BioGPS NCI60206504_atOVCAR3243.001102.550Details
BioGPS NCI60206504_atOVCAR48.617102.550Details
BioGPS NCI60206504_atOVCAR536.515102.550Details
BioGPS NCI60206504_atOVCAR86.703102.550Details
BioGPS NCI60206504_atPANC18.308102.550Details
BioGPS NCI60206504_atRL79.361102.550Details
BioGPS NCI60206504_atRPMI 8226219.649102.550Details
BioGPS NCI60206504_atRS118469.621102.550Details
BioGPS NCI60206504_atRXF3938.444102.550Details
BioGPS NCI60206504_atSAOS28.505102.550Details
BioGPS NCI60206504_atSF26847.196102.550Details
BioGPS NCI60206504_atSF2957.774102.550Details
BioGPS NCI60206504_atSF5396.813102.550Details
BioGPS NCI60206504_atSHSYSY+RA7.587102.550Details
BioGPS NCI60206504_atSHSYSY-RA7.869102.550Details
BioGPS NCI60206504_atSKMEL28.201102.550Details
BioGPS NCI60206504_atSKMEL288.552102.550Details
BioGPS NCI60206504_atSKMEL57.259102.550Details
BioGPS NCI60206504_atSKOV311.806102.550Details
BioGPS NCI60206504_atSN12C794.520102.550Details
BioGPS NCI60206504_atSNB196.841102.550Details
BioGPS NCI60206504_atSNB758.947102.550Details
BioGPS NCI60206504_atSR9.057102.550Details
BioGPS NCI60206504_atSW6209.438102.550Details
BioGPS NCI60206504_atT248.912102.550Details
BioGPS NCI60206504_atT3M410.134102.550Details
BioGPS NCI60206504_atTK108.227102.550Details
BioGPS NCI60206504_atU1187.370102.550Details
BioGPS NCI60206504_atU1386.695102.550Details
BioGPS NCI60206504_atU20S28.120102.550Details
BioGPS NCI60206504_atU25114.096102.550Details
BioGPS NCI60206504_atU877.186102.550Details
BioGPS NCI60206504_atUACC2577.377102.550Details
BioGPS NCI60206504_atUACC628.467102.550Details
BioGPS NCI60206504_atUO312327.566102.550Details
BioGPS NCI60206504_atZR75_19.966102.550Details
BioGPS NCI60206504_atastrocytes8.367102.550Details
BioGPS NCI60206504_athuh-79.764102.550Details