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Gene ID: 1586 | CYP17A1 Antibody Resource


CYP17A1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 17, subfamily A, polypeptide 1
Uniprot: 
P05093
Protein Name: 
steroid 17-alpha-hydroxylase/17,20 lyase
Nucleotide: 
NM_000102
Alias: 
CPT7;CYP17;S17AH;P450C17;
Ensembl: 
ENSG00000148795
Location: 
10q24.3
HPRD: 
01944
NCBI Gene: 
1586
MIM: 
609300

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
Function: 
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Subcellular location: 
Membrane Potential.
PTM: 
Phosphoprotein;
Disease: 
Adrenal hyperplasia 5 (AH5) [MIM:202110]: A form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. Congenital adrenal hyperplasia is characterized by androgen excess leading to ambiguous genitalia in affected females, rapid somatic growth during childhood in both sexes with premature closure of the epiphyses and short adult stature. Four clinical types: 'salt wasting' (SW, the most severe type), 'simple virilizing' (SV, less severely affected patients), with normal aldosterone biosynthesis, 'non-classic form' or late-onset (NC or LOAH)and 'cryptic' (asymptomatic). Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB02090 CYP17A1 Antibody (OAEB02090) Human WB 0.1mg $289 Details
Polyclonal Antibody OAAB04952 CYP17A1 antibody - center region (OAAB04952) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP60142_P050 CYP17A1 Antibody (ARP60142_P050) Polyclonal Bovine, Dog, Goat, Guinea pig, Horse, Human, Pig, Rabbit, Rat, Sheep Not tested 50 ug $125 Details
Polyclonal Antibody OAAF02936 CYP17A1 Antibody (OAAF02936) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all CYP17A1 antibodies


Product Images
CYP17A1 antibody - center region (OAAB04952) in K562 cells using Western Blot

Sample Type: K562

CYP17A1 Antibody (OAAF02936) in A549, Jurkat, HeLa cells using Western Blot

Sample Type: A549, Jurkat, HeLa

CYP17A1 Antibody (OAEB02090) in Human Ovary cells using Western Blot

Sample Type: Human Ovary


CYP17A1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP41405 Gobiocypris rarus CYP17A1 antibody G9JKN7 92.0%
ARP41405 American alligator CYP17A1 antibody; Alligator mississippiensis CYP17A1 antibody Q3SCK0 100.0%
ARP60142 American bison CYP17A1 antibody; Bison bison CYP17A1 antibody Q9GMC7 93.0%
ARP60142 Bovine CYP17A1 antibody; Bos taurus CYP17A1 antibody F1MJA7 93.0%
ARP60142 Bovine CYP17A1 antibody; Bos taurus CYP17A1 antibody P05185 93.0%
ARP60142 Cat CYP17A1 antibody; Felis catus CYP17A1 antibody Q9GMC8 100.0%
ARP60142 Cat CYP17A1 antibody; Felis catus CYP17A1 antibody M3VWA9 93.0%
ARP60142 Chacma baboon CYP17A1 antibody; Papio hamadryas ursinus CYP17A1 antibody Q9GLD2 100.0%
ARP41405 Channel catfish CYP17A1 antibody; Ictalurus punctatus CYP17A1 antibody O73853 92.0%
ARP60142 Chimpanzee CYP17A1 antibody; Pan troglodytes CYP17A1 antibody Q8HYN1 100.0%
ARP60142 Chimpanzee CYP17A1 antibody; Pan troglodytes CYP17A1 antibody H2RB49 100.0%
ARP60142 Crab-eating macaque CYP17A1 antibody; Macaca fascicularis CYP17A1 antibody Q2XVA1 100.0%
ARP60142 Crab-eating macaque CYP17A1 antibody; Macaca fascicularis CYP17A1 antibody B8K1T1 100.0%
ARP60142 Dog CYP17A1 antibody; Canis familiaris CYP17A1 antibody E2RKV5 100.0%
ARP60142 European domestic ferret CYP17A1 antibody; Mustela putorius furo CYP17A1 antibody M3YZJ5 85.0%
ARP60142 Giant panda CYP17A1 antibody; Ailuropoda melanoleuca CYP17A1 antibody D2GXX0 93.0%
ARP60142 Goat CYP17A1 antibody; Capra hircus CYP17A1 antibody Q9N0U7 93.0%
ARP41405 Green anole CYP17A1 antibody; Anolis carolinensis CYP17A1 antibody G1KCU3 83.0%
ARP60142 Guinea pig CYP17A1 antibody; Cavia porcellus CYP17A1 antibody Q64410 85.0%
ARP60142 Horse CYP17A1 antibody; Equus caballus CYP17A1 antibody Q95328 100.0%
ARP60142 Human CYP17A1 antibody; Homo sapiens CYP17A1 antibody Q1HB44 100.0%
ARP60142 Human CYP17A1 antibody; Homo sapiens CYP17A1 antibody P05093 100.0%
ARP41405 Japanese sea perch CYP17A1 antibody; Lateolabrax japonicus CYP17A1 antibody G1EFQ6 83.0%
ARP41405 Mangrove killifish CYP17A1 antibody; Kryptolebias marmoratus CYP17A1 antibody H5ZVK1 91.0%
ARP41405 Orange-spotted grouper CYP17A1 antibody; Epinephelus coioides CYP17A1 antibody C1KAE8 83.0%
ARP60142 Rabbit CYP17A1 antibody; Oryctolagus cuniculus CYP17A1 antibody G1TEG0 93.0%
ARP60142 Rat CYP17A1 antibody; Rattus norvegicus CYP17A1 antibody P11715 79.0%
ARP60142 Rhesus macaque CYP17A1 antibody; Macaca mulatta CYP17A1 antibody Q8HYM9 100.0%
ARP60142 Rhesus macaque CYP17A1 antibody; Macaca mulatta CYP17A1 antibody F6WI15 100.0%
ARP60142 Sheep CYP17A1 antibody; Ovis aries CYP17A1 antibody Q29497 93.0%
ARP60142 Small-eared galago CYP17A1 antibody; Otolemur garnettii CYP17A1 antibody H0X9A2 93.0%
ARP60142 Sumatran orangutan CYP17A1 antibody; Pongo abelii CYP17A1 antibody H2NBG5 93.0%
ARP60142 Thirteen-lined ground squirrel CYP17A1 antibody; Spermophilus tridecemlineatus CYP17A1 antibody I3MMZ9 79.0%
ARP41405 Three-spined stickleback CYP17A1 antibody; Gasterosteus aculeatus CYP17A1 antibody A7U486 83.0%
ARP41405 Three-spined stickleback CYP17A1 antibody; Gasterosteus aculeatus CYP17A1 antibody G3NDF2 83.0%
ARP41405 Three-spined stickleback CYP17A1 antibody; Gasterosteus aculeatus CYP17A1 antibody G3NDG0 83.0%
ARP60142 White-footed mouse CYP17A1 antibody; Peromyscus leucopus CYP17A1 antibody Q91Z85 82.0%
ARP60142 White-tufted-ear marmoset CYP17A1 antibody; Callithrix jacchus CYP17A1 antibody F6QQY3 100.0%
ARP60142 Yellow baboon CYP17A1 antibody; Papio cynocephalus CYP17A1 antibody Q8HYN0 100.0%
ARP41405 Zebrafish CYP17A1 antibody; Danio rerio CYP17A1 antibody Q1ECZ3 92.0%
ARP41405 Zebrafish CYP17A1 antibody; Danio rerio CYP17A1 antibody Q6PFI1 92.0%
ARP41405 Zebrafish CYP17A1 antibody; Danio rerio CYP17A1 antibody Q7T3J1 92.0%
ARP41405 Zebrafish CYP17A1 antibody; Danio rerio CYP17A1 antibody A2ATX9 92.0%
ARP41405 Zebrafish CYP17A1 antibody; Danio rerio CYP17A1 antibody B3DH80 92.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205502_at721_B_lymphoblasts5.550228.650Details
BioGPS Gene Atlas205502_atAdipocyte4.550228.650Details
BioGPS Gene Atlas205502_atAdrenalCortex7888.750228.650Details
BioGPS Gene Atlas205502_atAdrenalgland11557.350228.650Details
BioGPS Gene Atlas205502_atAmygdala4.800228.650Details
BioGPS Gene Atlas205502_atAppendix4.800228.650Details
BioGPS Gene Atlas205502_atAtrioventricularNode3.550228.650Details
BioGPS Gene Atlas205502_atBDCA4+_DentriticCells4.800228.650Details
BioGPS Gene Atlas205502_atBonemarrow4.800228.650Details
BioGPS Gene Atlas205502_atBronchialEpithelialCells4.500228.650Details
BioGPS Gene Atlas205502_atCD105+_Endothelial4.550228.650Details
BioGPS Gene Atlas205502_atCD14+_Monocytes4.850228.650Details
BioGPS Gene Atlas205502_atCD19+_BCells(neg._sel.)4.800228.650Details
BioGPS Gene Atlas205502_atCD33+_Myeloid5.750228.650Details
BioGPS Gene Atlas205502_atCD34+5.800228.650Details
BioGPS Gene Atlas205502_atCD4+_Tcells4.850228.650Details
BioGPS Gene Atlas205502_atCD56+_NKCells5.350228.650Details
BioGPS Gene Atlas205502_atCD71+_EarlyErythroid4.250228.650Details
BioGPS Gene Atlas205502_atCD8+_Tcells4.400228.650Details
BioGPS Gene Atlas205502_atCardiacMyocytes5.850228.650Details
BioGPS Gene Atlas205502_atCaudatenucleus4.100228.650Details
BioGPS Gene Atlas205502_atCerebellum3.750228.650Details
BioGPS Gene Atlas205502_atCerebellumPeduncles5.250228.650Details
BioGPS Gene Atlas205502_atCiliaryGanglion3.200228.650Details
BioGPS Gene Atlas205502_atCingulateCortex4.700228.650Details
BioGPS Gene Atlas205502_atColorectaladenocarcinoma4.550228.650Details
BioGPS Gene Atlas205502_atDorsalRootGanglion3.550228.650Details
BioGPS Gene Atlas205502_atFetalThyroid4.450228.650Details
BioGPS Gene Atlas205502_atFetalbrain4.500228.650Details
BioGPS Gene Atlas205502_atFetalliver3.950228.650Details
BioGPS Gene Atlas205502_atFetallung3.750228.650Details
BioGPS Gene Atlas205502_atGlobusPallidus3.500228.650Details
BioGPS Gene Atlas205502_atHeart5.950228.650Details
BioGPS Gene Atlas205502_atHypothalamus4.950228.650Details
BioGPS Gene Atlas205502_atKidney111.400228.650Details
BioGPS Gene Atlas205502_atLeukemia_chronicMyelogenousK-5624.100228.650Details
BioGPS Gene Atlas205502_atLeukemia_promyelocytic-HL-604.050228.650Details
BioGPS Gene Atlas205502_atLeukemialymphoblastic(MOLT-4)3.700228.650Details
BioGPS Gene Atlas205502_atLiver6.450228.650Details
BioGPS Gene Atlas205502_atLung5.000228.650Details
BioGPS Gene Atlas205502_atLymphnode16.800228.650Details
BioGPS Gene Atlas205502_atLymphoma_burkitts(Daudi)5.900228.650Details
BioGPS Gene Atlas205502_atLymphoma_burkitts(Raji)6.500228.650Details
BioGPS Gene Atlas205502_atMedullaOblongata4.200228.650Details
BioGPS Gene Atlas205502_atOccipitalLobe4.050228.650Details
BioGPS Gene Atlas205502_atOlfactoryBulb3.600228.650Details
BioGPS Gene Atlas205502_atOvary3.050228.650Details
BioGPS Gene Atlas205502_atPancreas3.700228.650Details
BioGPS Gene Atlas205502_atPancreaticIslet4.950228.650Details
BioGPS Gene Atlas205502_atParietalLobe4.900228.650Details
BioGPS Gene Atlas205502_atPituitary5.300228.650Details
BioGPS Gene Atlas205502_atPlacenta4.750228.650Details
BioGPS Gene Atlas205502_atPons4.350228.650Details
BioGPS Gene Atlas205502_atPrefrontalCortex5.600228.650Details
BioGPS Gene Atlas205502_atProstate5.350228.650Details
BioGPS Gene Atlas205502_atSalivarygland3.700228.650Details
BioGPS Gene Atlas205502_atSkeletalMuscle5.550228.650Details
BioGPS Gene Atlas205502_atSkin3.550228.650Details
BioGPS Gene Atlas205502_atSmoothMuscle5.200228.650Details
BioGPS Gene Atlas205502_atSpinalcord4.900228.650Details
BioGPS Gene Atlas205502_atSubthalamicNucleus4.250228.650Details
BioGPS Gene Atlas205502_atSuperiorCervicalGanglion5.400228.650Details
BioGPS Gene Atlas205502_atTemporalLobe4.200228.650Details
BioGPS Gene Atlas205502_atTestis42.600228.650Details
BioGPS Gene Atlas205502_atTestisGermCell6.350228.650Details
BioGPS Gene Atlas205502_atTestisIntersitial50.800228.650Details
BioGPS Gene Atlas205502_atTestisLeydigCell72.800228.650Details
BioGPS Gene Atlas205502_atTestisSeminiferousTubule3.900228.650Details
BioGPS Gene Atlas205502_atThalamus4.650228.650Details
BioGPS Gene Atlas205502_atThymus3.600228.650Details
BioGPS Gene Atlas205502_atThyroid5.850228.650Details
BioGPS Gene Atlas205502_atTongue4.550228.650Details
BioGPS Gene Atlas205502_atTonsil4.450228.650Details
BioGPS Gene Atlas205502_atTrachea3.950228.650Details
BioGPS Gene Atlas205502_atTrigeminalGanglion4.750228.650Details
BioGPS Gene Atlas205502_atUterus3.700228.650Details
BioGPS Gene Atlas205502_atUterusCorpus4.250228.650Details
BioGPS Gene Atlas205502_atWholeBlood5.000228.650Details
BioGPS Gene Atlas205502_atWholebrain3.750228.650Details
BioGPS Gene Atlas205502_atcolon4.600228.650Details
BioGPS Gene Atlas205502_atpineal_day5.680228.650Details
BioGPS Gene Atlas205502_atpineal_night5.540228.650Details
BioGPS Gene Atlas205502_atretina5.550228.650Details
BioGPS Gene Atlas205502_atsmall_intestine4.400228.650Details
BioGPS NCI60205502_at7864.8994.840Details
BioGPS NCI60205502_atA1724.5924.840Details
BioGPS NCI60205502_atA2044.7954.840Details
BioGPS NCI60205502_atA3614.8694.840Details
BioGPS NCI60205502_atA4984.8364.840Details
BioGPS NCI60205502_atA5494.9124.840Details
BioGPS NCI60205502_atACC34.9444.840Details
BioGPS NCI60205502_atACHN4.6044.840Details
BioGPS NCI60205502_atALVA315.0464.840Details
BioGPS NCI60205502_atCAKI14.9334.840Details
BioGPS NCI60205502_atCCRT CEM5.8874.840Details
BioGPS NCI60205502_atCOLO2054.8474.840Details
BioGPS NCI60205502_atDLD14.7424.840Details
BioGPS NCI60205502_atDU1454.6434.840Details
BioGPS NCI60205502_atEKVX4.7124.840Details
BioGPS NCI60205502_atGM1334.9364.840Details
BioGPS NCI60205502_atGM16004.9354.840Details
BioGPS NCI60205502_atGM23134.8754.840Details
BioGPS NCI60205502_atGM23454.8354.840Details
BioGPS NCI60205502_atGM24934.9294.840Details
BioGPS NCI60205502_atGM975.2584.840Details
BioGPS NCI60205502_atHCC29984.5024.840Details
BioGPS NCI60205502_atHCT1164.8444.840Details
BioGPS NCI60205502_atHCT154.6364.840Details
BioGPS NCI60205502_atHEK 293 T-rex4.9104.840Details
BioGPS NCI60205502_atHEK 293T4.8154.840Details
BioGPS NCI60205502_atHEK2934.7584.840Details
BioGPS NCI60205502_atHELA4.6304.840Details
BioGPS NCI60205502_atHEPG24.8234.840Details
BioGPS NCI60205502_atHL605.0724.840Details
BioGPS NCI60205502_atHOP624.8444.840Details
BioGPS NCI60205502_atHOP924.6184.840Details
BioGPS NCI60205502_atHS578T4.7644.840Details
BioGPS NCI60205502_atHSG4.7104.840Details
BioGPS NCI60205502_atHT10804.7934.840Details
BioGPS NCI60205502_atHT294.9804.840Details
BioGPS NCI60205502_atIGROV14.7834.840Details
BioGPS NCI60205502_atIOSE804.7904.840Details
BioGPS NCI60205502_atJURKAT4.8264.840Details
BioGPS NCI60205502_atK5625.0734.840Details
BioGPS NCI60205502_atKM125.0514.840Details
BioGPS NCI60205502_atLN184.5974.840Details
BioGPS NCI60205502_atLNCAP4.8414.840Details
BioGPS NCI60205502_atLOX IMVI4.8234.840Details
BioGPS NCI60205502_atM144.7764.840Details
BioGPS NCI60205502_atMALME 3M5.1384.840Details
BioGPS NCI60205502_atMCF74.7054.840Details
BioGPS NCI60205502_atMD MB2314.8914.840Details
BioGPS NCI60205502_atMDA MB4355.4394.840Details
BioGPS NCI60205502_atMOLT44.9394.840Details
BioGPS NCI60205502_atNCI 4605.0104.840Details
BioGPS NCI60205502_atNCI H2265.0014.840Details
BioGPS NCI60205502_atNCI H234.8804.840Details
BioGPS NCI60205502_atNCI H322M4.8494.840Details
BioGPS NCI60205502_atNCVADR RES4.5774.840Details
BioGPS NCI60205502_atOVCAR35.1164.840Details
BioGPS NCI60205502_atOVCAR44.8144.840Details
BioGPS NCI60205502_atOVCAR54.7724.840Details
BioGPS NCI60205502_atOVCAR84.6114.840Details
BioGPS NCI60205502_atPANC14.9014.840Details
BioGPS NCI60205502_atRL75.0124.840Details
BioGPS NCI60205502_atRPMI 82264.9064.840Details
BioGPS NCI60205502_atRS118465.2714.840Details
BioGPS NCI60205502_atRXF3934.7984.840Details
BioGPS NCI60205502_atSAOS24.8974.840Details
BioGPS NCI60205502_atSF2684.8274.840Details
BioGPS NCI60205502_atSF2954.7584.840Details
BioGPS NCI60205502_atSF5394.6324.840Details
BioGPS NCI60205502_atSHSYSY+RA4.7284.840Details
BioGPS NCI60205502_atSHSYSY-RA4.7734.840Details
BioGPS NCI60205502_atSKMEL24.8084.840Details
BioGPS NCI60205502_atSKMEL284.8434.840Details
BioGPS NCI60205502_atSKMEL54.7344.840Details
BioGPS NCI60205502_atSKOV34.9624.840Details
BioGPS NCI60205502_atSN12C4.7994.840Details
BioGPS NCI60205502_atSNB194.6064.840Details
BioGPS NCI60205502_atSNB754.8074.840Details
BioGPS NCI60205502_atSR4.9204.840Details
BioGPS NCI60205502_atSW6204.9744.840Details
BioGPS NCI60205502_atT244.9394.840Details
BioGPS NCI60205502_atT3M44.9944.840Details
BioGPS NCI60205502_atTK104.7994.840Details
BioGPS NCI60205502_atU1184.7104.840Details
BioGPS NCI60205502_atU1384.4844.840Details
BioGPS NCI60205502_atU20S4.6804.840Details
BioGPS NCI60205502_atU2514.7804.840Details
BioGPS NCI60205502_atU874.7054.840Details
BioGPS NCI60205502_atUACC2574.7634.840Details
BioGPS NCI60205502_atUACC624.9524.840Details
BioGPS NCI60205502_atUO314.6254.840Details
BioGPS NCI60205502_atZR75_15.0994.840Details
BioGPS NCI60205502_atastrocytes4.8274.840Details
BioGPS NCI60205502_athuh-74.9304.840Details