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Gene ID: 1584 | CYP11B1 Antibody Resource


CYP11B1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 11, subfamily B, polypeptide 1
Uniprot: 
P15538
Protein Name: 
cytochrome P450 11B1, mitochondrial
Nucleotide: 
NM_001026213
Alias: 
FHI;CPN1;CYP11B;P450C11;
Ensembl: 
ENSG00000160882
Location: 
8q21
HPRD: 
01943
NCBI Gene: 
1584
MIM: 
610613

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Function: 
Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
Subcellular location: 
Mitochondrion membrane.
PTM: 
Disease: 
Adrenal hyperplasia 4 (AH4) [MIM:202010]: A form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. Congenital adrenal hyperplasia is characterized by androgen excess leading to ambiguous genitalia in affected females, rapid somatic growth during childhood in both sexes with premature closure of the epiphyses and short adult stature. Four clinical types: 'salt wasting' (SW, the most severe type), 'simple virilizing' (SV, less severely affected patients), with normal aldosterone biosynthesis, 'non-classic form' or late-onset (NC or LOAH)and 'cryptic' (asymptomatic). Note: The disease is caused by mutations affecting the gene represented in this entry. Familial hyperaldosteronism 1 (FH1) [MIM:103900]: A disorder characterized by hypertension, variable hyperaldosteronism, and abnormal adrenal steroid production, including 18-oxocortisol and 18-hydroxycortisol. There is significant phenotypic heterogeneity, and some individuals never develop hypertension. Note: The disease is caused by mutations affecting the gene represented in this entry. The molecular defect causing hyperaldosteronism familial 1 is an anti-Lepore-type fusion of the CYP11B1 and CYP11B2 genes. The hybrid gene has the promoting part of CYP11B1, ACTH-sensitive, and the coding part of CYP11B2.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP60140_P050 CYP11B1 antibody - C-terminal region (ARP60140_P050) Polyclonal Human IHC, WB 50ug $289 Details
Polyclonal Antibody ARP60141_P050 CYP11B1 antibody - middle region (ARP60141_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody OAAB05320 CYP11B1 antibody - N-terminal region (OAAB05320) Human WB, FC, IHC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB05321 CYP11B1 antibody - C-terminal region (OAAB05321) Human WB, IHC, FC, ELISA 400ul $289 Details
Polyclonal Antibody OAEC03282 Cytochrome P450 11B1/2 Antibody (OAEC03282) Human WB, ELISA 100ug $229 Details
Polyclonal Antibody OAAF04550 CYP11B1 Antibody (OAAF04550) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all CYP11B1 antibodies


Product Images
CYP11B1 antibody - C-terminal region (ARP60140_P050) in Human Liver cells using Western Blot

Sample Type: Human Liver

CYP11B1 antibody - C-terminal region (ARP60140_P050) in Monkey adrenal gland cells using Immunohistochemistry

Sample Type: Monkey adrenal gland

CYP11B1 antibody - C-terminal region (ARP60140_P050) in Monkey vagina cells using Immunohistochemistry

Sample Type: Monkey vagina

CYP11B1 antibody - C-terminal region (ARP60140_P050) in r-CYP11B1 cells using Western Blot

Sample Type: r-CYP11B1

CYP11B1 antibody - middle region (ARP60141_P050) in Human HeLa cells using Western Blot

Sample Type: Human HeLa

CYP11B1 antibody - N-terminal region (OAAB05320) in human lung carcinoma cells using Immunohistochemistry

Sample Type: human lung carcinoma

CYP11B1 antibody - N-terminal region (OAAB05320) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart

CYP11B1 antibody - N-terminal region (OAAB05320) in NCI-H460 cells using Flow Cytometry

Sample Type: NCI-H460

CYP11B1 antibody - C-terminal region (OAAB05321) in human brain carcinoma cells using Immunohistochemistry

Sample Type: human brain carcinoma

CYP11B1 antibody - C-terminal region (OAAB05321) in MDA-MB231 cells using Flow Cytometry

Sample Type: MDA-MB231

CYP11B1 antibody - C-terminal region (OAAB05321) in MDA-MB435 cells using Western Blot

Sample Type: MDA-MB435

CYP11B1 Antibody (OAAF04550) in COLO205 cells using Western Blot

Sample Type: COLO205

Cytochrome P450 11B1/2 Antibody (OAEC03282) in COLO205 cells using Western Blot

Sample Type: COLO205


CYP11B1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60140 Chacma baboon CYP11B1 antibody; Papio hamadryas ursinus CYP11B1 antibody Q29527 100.0%
ARP60140 Chacma baboon CYP11B1 antibody; Papio hamadryas ursinus CYP11B1 antibody Q8MIJ8 100.0%
ARP60141 Chacma baboon CYP11B1 antibody; Papio hamadryas ursinus CYP11B1 antibody Q29527 93.0%
ARP60141 Chacma baboon CYP11B1 antibody; Papio hamadryas ursinus CYP11B1 antibody Q8MIJ8 93.0%
ARP41750 Chacma baboon CYP11B1 antibody; Papio hamadryas ursinus CYP11B1 antibody Q29527 86.0%
ARP41750 Chacma baboon CYP11B1 antibody; Papio hamadryas ursinus CYP11B1 antibody Q8MIJ8 86.0%
ARP60140 Chimpanzee CYP11B1 antibody; Pan troglodytes CYP11B1 antibody H2QWT4 100.0%
ARP60141 Chimpanzee CYP11B1 antibody; Pan troglodytes CYP11B1 antibody H2QWT4 100.0%
ARP41750 Chimpanzee CYP11B1 antibody; Pan troglodytes CYP11B1 antibody H2QWT4 86.0%
ARP41749 Chimpanzee CYP11B1 antibody; Pan troglodytes CYP11B1 antibody H2QWT4 79.0%
ARP60140 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538 100.0%
ARP60141 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538 100.0%
ARP60140 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody Q4VAR0 100.0%
ARP60141 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody Q4VAR0 100.0%
ARP60141 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody Q8TE39 100.0%
ARP60140 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody H0YBR4 100.0%
ARP60140 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538-2 100.0%
ARP60141 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538-2 100.0%
ARP41750 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538 79.0%
ARP41749 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody Q4VAR0 79.0%
ARP41750 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody Q4VAR0 79.0%
ARP41750 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody Q8TE38 79.0%
ARP41749 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody Q8TE39 79.0%
ARP41750 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody H0YBR4 79.0%
ARP41749 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538-2 79.0%
ARP41750 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538-2 79.0%
ARP41749 Human CYP11B1 antibody; Homo sapiens CYP11B1 antibody P15538 79.0%
ARP60140 Pig CYP11B1 antibody; Sus scrofa CYP11B1 antibody Q29552 79.0%
ARP60140 Sheep CYP11B1 antibody; Ovis aries CYP11B1 antibody P51663 79.0%
ARP60140 Sumatran orangutan CYP11B1 antibody; Pongo abelii CYP11B1 antibody H2PRB9 100.0%
ARP60141 Sumatran orangutan CYP11B1 antibody; Pongo abelii CYP11B1 antibody H2PRB9 100.0%
ARP41750 Sumatran orangutan CYP11B1 antibody; Pongo abelii CYP11B1 antibody H2PRB9 86.0%
ARP41749 Sumatran orangutan CYP11B1 antibody; Pongo abelii CYP11B1 antibody H2PRB9 79.0%
ARP41749 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HEB9 93.0%
ARP60140 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HEB9 93.0%
ARP60141 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HEB9 93.0%
ARP41749 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HEK5 93.0%
ARP60140 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HEK5 93.0%
ARP60141 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HEK5 93.0%
ARP41749 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HJJ9 93.0%
ARP60140 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HJJ9 93.0%
ARP60141 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HJJ9 93.0%
ARP41750 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HEK5 85.0%
ARP41750 White-tufted-ear marmoset CYP11B1 antibody; Callithrix jacchus CYP11B1 antibody F7HJJ9 85.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas214610_at721_B_lymphoblasts6.850179.810Details
BioGPS Gene Atlas214610_atAdipocyte6.100179.810Details
BioGPS Gene Atlas214610_atAdrenalCortex9768.800179.810Details
BioGPS Gene Atlas214610_atAdrenalgland5515.400179.810Details
BioGPS Gene Atlas214610_atAmygdala6.500179.810Details
BioGPS Gene Atlas214610_atAppendix6.900179.810Details
BioGPS Gene Atlas214610_atAtrioventricularNode5.050179.810Details
BioGPS Gene Atlas214610_atBDCA4+_DentriticCells6.100179.810Details
BioGPS Gene Atlas214610_atBonemarrow6.550179.810Details
BioGPS Gene Atlas214610_atBronchialEpithelialCells5.950179.810Details
BioGPS Gene Atlas214610_atCD105+_Endothelial6.100179.810Details
BioGPS Gene Atlas214610_atCD14+_Monocytes6.450179.810Details
BioGPS Gene Atlas214610_atCD19+_BCells(neg._sel.)6.400179.810Details
BioGPS Gene Atlas214610_atCD33+_Myeloid7.600179.810Details
BioGPS Gene Atlas214610_atCD34+7.700179.810Details
BioGPS Gene Atlas214610_atCD4+_Tcells6.750179.810Details
BioGPS Gene Atlas214610_atCD56+_NKCells6.800179.810Details
BioGPS Gene Atlas214610_atCD71+_EarlyErythroid5.850179.810Details
BioGPS Gene Atlas214610_atCD8+_Tcells5.800179.810Details
BioGPS Gene Atlas214610_atCardiacMyocytes7.750179.810Details
BioGPS Gene Atlas214610_atCaudatenucleus5.550179.810Details
BioGPS Gene Atlas214610_atCerebellum4.950179.810Details
BioGPS Gene Atlas214610_atCerebellumPeduncles7.150179.810Details
BioGPS Gene Atlas214610_atCiliaryGanglion5.000179.810Details
BioGPS Gene Atlas214610_atCingulateCortex6.450179.810Details
BioGPS Gene Atlas214610_atColorectaladenocarcinoma6.100179.810Details
BioGPS Gene Atlas214610_atDorsalRootGanglion5.050179.810Details
BioGPS Gene Atlas214610_atFetalThyroid5.950179.810Details
BioGPS Gene Atlas214610_atFetalbrain6.150179.810Details
BioGPS Gene Atlas214610_atFetalliver5.450179.810Details
BioGPS Gene Atlas214610_atFetallung4.850179.810Details
BioGPS Gene Atlas214610_atGlobusPallidus4.650179.810Details
BioGPS Gene Atlas214610_atHeart10.100179.810Details
BioGPS Gene Atlas214610_atHypothalamus6.750179.810Details
BioGPS Gene Atlas214610_atKidney5.400179.810Details
BioGPS Gene Atlas214610_atLeukemia_chronicMyelogenousK-5625.500179.810Details
BioGPS Gene Atlas214610_atLeukemia_promyelocytic-HL-605.400179.810Details
BioGPS Gene Atlas214610_atLeukemialymphoblastic(MOLT-4)4.750179.810Details
BioGPS Gene Atlas214610_atLiver8.400179.810Details
BioGPS Gene Atlas214610_atLung6.800179.810Details
BioGPS Gene Atlas214610_atLymphnode5.150179.810Details
BioGPS Gene Atlas214610_atLymphoma_burkitts(Daudi)7.750179.810Details
BioGPS Gene Atlas214610_atLymphoma_burkitts(Raji)8.700179.810Details
BioGPS Gene Atlas214610_atMedullaOblongata5.650179.810Details
BioGPS Gene Atlas214610_atOccipitalLobe5.500179.810Details
BioGPS Gene Atlas214610_atOlfactoryBulb4.850179.810Details
BioGPS Gene Atlas214610_atOvary4.300179.810Details
BioGPS Gene Atlas214610_atPancreas4.900179.810Details
BioGPS Gene Atlas214610_atPancreaticIslet6.500179.810Details
BioGPS Gene Atlas214610_atParietalLobe6.700179.810Details
BioGPS Gene Atlas214610_atPituitary7.050179.810Details
BioGPS Gene Atlas214610_atPlacenta6.050179.810Details
BioGPS Gene Atlas214610_atPons6.050179.810Details
BioGPS Gene Atlas214610_atPrefrontalCortex7.750179.810Details
BioGPS Gene Atlas214610_atProstate7.050179.810Details
BioGPS Gene Atlas214610_atSalivarygland4.800179.810Details
BioGPS Gene Atlas214610_atSkeletalMuscle8.400179.810Details
BioGPS Gene Atlas214610_atSkin4.950179.810Details
BioGPS Gene Atlas214610_atSmoothMuscle6.900179.810Details
BioGPS Gene Atlas214610_atSpinalcord6.550179.810Details
BioGPS Gene Atlas214610_atSubthalamicNucleus5.550179.810Details
BioGPS Gene Atlas214610_atSuperiorCervicalGanglion7.150179.810Details
BioGPS Gene Atlas214610_atTemporalLobe5.700179.810Details
BioGPS Gene Atlas214610_atTestis5.300179.810Details
BioGPS Gene Atlas214610_atTestisGermCell5.100179.810Details
BioGPS Gene Atlas214610_atTestisIntersitial5.250179.810Details
BioGPS Gene Atlas214610_atTestisLeydigCell6.300179.810Details
BioGPS Gene Atlas214610_atTestisSeminiferousTubule5.250179.810Details
BioGPS Gene Atlas214610_atThalamus6.350179.810Details
BioGPS Gene Atlas214610_atThymus4.600179.810Details
BioGPS Gene Atlas214610_atThyroid7.350179.810Details
BioGPS Gene Atlas214610_atTongue6.650179.810Details
BioGPS Gene Atlas214610_atTonsil6.100179.810Details
BioGPS Gene Atlas214610_atTrachea5.100179.810Details
BioGPS Gene Atlas214610_atTrigeminalGanglion7.600179.810Details
BioGPS Gene Atlas214610_atUterus4.900179.810Details
BioGPS Gene Atlas214610_atUterusCorpus5.850179.810Details
BioGPS Gene Atlas214610_atWholeBlood6.600179.810Details
BioGPS Gene Atlas214610_atWholebrain5.250179.810Details
BioGPS Gene Atlas214610_atcolon6.100179.810Details
BioGPS Gene Atlas214610_atpineal_day7.500179.810Details
BioGPS Gene Atlas214610_atpineal_night7.340179.810Details
BioGPS Gene Atlas214610_atretina7.400179.810Details
BioGPS Gene Atlas214610_atsmall_intestine5.850179.810Details
BioGPS NCI60214610_at7863.7093.670Details
BioGPS NCI60214610_atA1723.5213.670Details
BioGPS NCI60214610_atA2043.6123.670Details
BioGPS NCI60214610_atA3613.7153.670Details
BioGPS NCI60214610_atA4983.6563.670Details
BioGPS NCI60214610_atA5493.6873.670Details
BioGPS NCI60214610_atACC33.7813.670Details
BioGPS NCI60214610_atACHN3.3463.670Details
BioGPS NCI60214610_atALVA313.7333.670Details
BioGPS NCI60214610_atCAKI13.7223.670Details
BioGPS NCI60214610_atCCRT CEM5.0263.670Details
BioGPS NCI60214610_atCOLO2053.6113.670Details
BioGPS NCI60214610_atDLD13.5983.670Details
BioGPS NCI60214610_atDU1453.3703.670Details
BioGPS NCI60214610_atEKVX3.4393.670Details
BioGPS NCI60214610_atGM1333.6753.670Details
BioGPS NCI60214610_atGM16003.6853.670Details
BioGPS NCI60214610_atGM23133.6803.670Details
BioGPS NCI60214610_atGM23453.6423.670Details
BioGPS NCI60214610_atGM24933.7453.670Details
BioGPS NCI60214610_atGM974.6643.670Details
BioGPS NCI60214610_atHCC29983.2583.670Details
BioGPS NCI60214610_atHCT1163.6283.670Details
BioGPS NCI60214610_atHCT153.2953.670Details
BioGPS NCI60214610_atHEK 293 T-rex4.0753.670Details
BioGPS NCI60214610_atHEK 293T3.6943.670Details
BioGPS NCI60214610_atHEK2933.7253.670Details
BioGPS NCI60214610_atHELA3.2723.670Details
BioGPS NCI60214610_atHEPG23.6313.670Details
BioGPS NCI60214610_atHL604.1893.670Details
BioGPS NCI60214610_atHOP623.6563.670Details
BioGPS NCI60214610_atHOP923.5963.670Details
BioGPS NCI60214610_atHS578T3.6263.670Details
BioGPS NCI60214610_atHSG3.4063.670Details
BioGPS NCI60214610_atHT10803.5273.670Details
BioGPS NCI60214610_atHT293.7733.670Details
BioGPS NCI60214610_atIGROV13.5653.670Details
BioGPS NCI60214610_atIOSE803.6453.670Details
BioGPS NCI60214610_atJURKAT3.6953.670Details
BioGPS NCI60214610_atK5624.2543.670Details
BioGPS NCI60214610_atKM123.7173.670Details
BioGPS NCI60214610_atLN183.4743.670Details
BioGPS NCI60214610_atLNCAP3.6553.670Details
BioGPS NCI60214610_atLOX IMVI3.6263.670Details
BioGPS NCI60214610_atM143.6173.670Details
BioGPS NCI60214610_atMALME 3M3.7583.670Details
BioGPS NCI60214610_atMCF73.4443.670Details
BioGPS NCI60214610_atMD MB2313.6943.670Details
BioGPS NCI60214610_atMDA MB4353.8343.670Details
BioGPS NCI60214610_atMOLT43.6923.670Details
BioGPS NCI60214610_atNCI 4603.6963.670Details
BioGPS NCI60214610_atNCI H2263.6973.670Details
BioGPS NCI60214610_atNCI H233.6123.670Details
BioGPS NCI60214610_atNCI H322M3.6383.670Details
BioGPS NCI60214610_atNCVADR RES3.4063.670Details
BioGPS NCI60214610_atOVCAR33.7353.670Details
BioGPS NCI60214610_atOVCAR43.6143.670Details
BioGPS NCI60214610_atOVCAR53.5953.670Details
BioGPS NCI60214610_atOVCAR83.5453.670Details
BioGPS NCI60214610_atPANC13.7203.670Details
BioGPS NCI60214610_atRL73.6863.670Details
BioGPS NCI60214610_atRPMI 82263.6693.670Details
BioGPS NCI60214610_atRS118464.0493.670Details
BioGPS NCI60214610_atRXF3933.6333.670Details
BioGPS NCI60214610_atSAOS23.7083.670Details
BioGPS NCI60214610_atSF2683.6193.670Details
BioGPS NCI60214610_atSF2953.5783.670Details
BioGPS NCI60214610_atSF5393.2703.670Details
BioGPS NCI60214610_atSHSYSY+RA3.5763.670Details
BioGPS NCI60214610_atSHSYSY-RA3.6153.670Details
BioGPS NCI60214610_atSKMEL23.6433.670Details
BioGPS NCI60214610_atSKMEL283.6533.670Details
BioGPS NCI60214610_atSKMEL53.5083.670Details
BioGPS NCI60214610_atSKOV33.6913.670Details
BioGPS NCI60214610_atSN12C3.5993.670Details
BioGPS NCI60214610_atSNB193.3953.670Details
BioGPS NCI60214610_atSNB753.6203.670Details
BioGPS NCI60214610_atSR3.7313.670Details
BioGPS NCI60214610_atSW6203.7923.670Details
BioGPS NCI60214610_atT243.6933.670Details
BioGPS NCI60214610_atT3M43.8263.670Details
BioGPS NCI60214610_atTK103.5963.670Details
BioGPS NCI60214610_atU1183.6213.670Details
BioGPS NCI60214610_atU1383.4823.670Details
BioGPS NCI60214610_atU20S3.5713.670Details
BioGPS NCI60214610_atU2513.5393.670Details
BioGPS NCI60214610_atU873.5563.670Details
BioGPS NCI60214610_atUACC2573.6023.670Details
BioGPS NCI60214610_atUACC623.7673.670Details
BioGPS NCI60214610_atUO313.4183.670Details
BioGPS NCI60214610_atZR75_13.6893.670Details
BioGPS NCI60214610_atastrocytes3.7343.670Details
BioGPS NCI60214610_athuh-73.8923.670Details