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Gene ID: 1583 | CYP11A1 Antibody Resource


CYP11A1 Antibody Resource
Gene Full Name: 
cytochrome P450, family 11, subfamily A, polypeptide 1
Uniprot: 
P05108
Protein Name: 
cholesterol side-chain cleavage enzyme, mitochondrial
Nucleotide: 
NM_000781
Alias: 
CYP11A;CYPXIA1;P450SCC;
Ensembl: 
ENSG00000140459
Location: 
15q23-q24
HPRD: 
00326
NCBI Gene: 
1583
MIM: 
118485

Summary: 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
Function: 
Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.
Subcellular location: 
Mitochondrion membrane.
PTM: 
Disease: 
Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) [MIM:613743]: A rare disorder that can present as acute adrenal insufficiency in infancy or childhood. ACTH and plasma renin activity are elevated and adrenal steroids are inappropriately low or absent; the 46,XY patients have female external genitalia, sometimes with clitoromegaly. The phenotypic spectrum ranges from prematurity, complete underandrogenization, and severe early-onset adrenal failure to term birth with clitoromegaly and later-onset adrenal failure. Patients with congenital adrenal insufficiency do not manifest the massive adrenal enlargement typical of congenital lipoid adrenal hyperplasia. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP51905_P050 CYP11A1 antibody - middle region (ARP51905_P050) Polyclonal Human IHC, WB 50ug $289 Details
Polyclonal Antibody OASA08637 Cyp11a1 Antibody (OASA08637) IHC-AFF, WB, IHC-FFPE 0.1ml $765 Details
Polyclonal Antibody OAAB04982 CYP11A1 antibody - N-terminal region (OAAB04982) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP51906_P050 CYP11A1 Antibody (ARP51906_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody OAEC03284 Cytochrome P450 11A1 Antibody (OAEC03284) Human WB, ELISA 100ug $229 Details
Polyclonal Antibody OAAF04552 CYP11A1 Antibody (OAAF04552) Polyclonal Human WB, ELISA 100 ug $289 Details

Show all CYP11A1 antibodies


Product Images
CYP11A1 antibody - middle region (ARP51905_P050) in Hum. Fetal Liver cells using Western Blot

Sample Type: Hum. Fetal Liver

CYP11A1 antibody - middle region (ARP51905_P050) in Human HeLa cells using Western Blot

Sample Type: Human HeLa

CYP11A1 antibody - middle region (ARP51905_P050) in Human Hela cells using Western Blot

Sample Type: Human Hela

CYP11A1 antibody - middle region (ARP51905_P050) in Human HK2 cells using Immunohistochemistry

Sample Type: Human HK2

CYP11A1 antibody - middle region (ARP51905_P050) in Human HK2 cells using Immunohistochemistry

Sample Type: Human HK2

CYP11A1 antibody - middle region (ARP51905_P050) in Human HK2 cells using Immunohistochemistry

Sample Type: Human HK2

CYP11A1 antibody - middle region (ARP51905_P050) in Human Placenta cells using Immunohistochemistry

Sample Type: Human Placenta

CYP11A1 antibody - N-terminal region (OAAB04982) in HepG2 cells using Western Blot

Sample Type: HepG2

CYP11A1 Antibody (OAAF04552) in HeLa, A549 cells using Western Blot

Sample Type: HeLa, A549

Cytochrome P450 11A1 Antibody (OAEC03284) in Human Hela cells using Western Blot

Sample Type: Human Hela


CYP11A1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP51906 Chacma baboon CYP11A1 antibody; Papio hamadryas ursinus CYP11A1 antibody Q66VB4 100.0%
ARP51905 Chacma baboon CYP11A1 antibody; Papio hamadryas ursinus CYP11A1 antibody Q66VB4 93.0%
ARP51906 Crab-eating macaque CYP11A1 antibody; Macaca fascicularis CYP11A1 antibody Q2XV99 100.0%
ARP51905 Crab-eating macaque CYP11A1 antibody; Macaca fascicularis CYP11A1 antibody Q2XV99 93.0%
ARP51905 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody E7EPP8 100.0%
ARP51906 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody E7EPP8 100.0%
ARP51905 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody H3BSZ1 100.0%
ARP51906 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody H3BSZ1 100.0%
ARP51905 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody P05108-2 100.0%
ARP51906 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody P05108-2 100.0%
ARP51905 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody P05108 100.0%
ARP51906 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody P05108 100.0%
ARP51905 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody Q2HZF3 100.0%
ARP51906 Human CYP11A1 antibody; Homo sapiens CYP11A1 antibody Q2HZF3 100.0%
ARP51906 Rabbit CYP11A1 antibody; Oryctolagus cuniculus CYP11A1 antibody G1U3L3 83.0%
ARP51906 Rabbit CYP11A1 antibody; Oryctolagus cuniculus CYP11A1 antibody Q28827 83.0%
ARP51906 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7DNQ0 100.0%
ARP51906 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7GRM8 100.0%
ARP51906 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7GRN0 100.0%
ARP51906 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7GRN2 100.0%
ARP51905 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7DNQ0 93.0%
ARP51905 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7GRM8 93.0%
ARP51905 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7GRN0 93.0%
ARP51905 Rhesus macaque CYP11A1 antibody; Macaca mulatta CYP11A1 antibody F7GRN2 93.0%
ARP51905 Sumatran orangutan CYP11A1 antibody; Pongo abelii CYP11A1 antibody H2NPF0 100.0%
ARP51906 Sumatran orangutan CYP11A1 antibody; Pongo abelii CYP11A1 antibody H2NPF0 100.0%
ARP51906 White-tufted-ear marmoset CYP11A1 antibody; Callithrix jacchus CYP11A1 antibody U3EDR8 86.0%
ARP51906 White-tufted-ear marmoset CYP11A1 antibody; Callithrix jacchus CYP11A1 antibody F6ZLD0 86.0%
ARP51906 White-tufted-ear marmoset CYP11A1 antibody; Callithrix jacchus CYP11A1 antibody F7HGJ9 86.0%
ARP51905 White-tufted-ear marmoset CYP11A1 antibody; Callithrix jacchus CYP11A1 antibody U3EDR8 79.0%
ARP51905 White-tufted-ear marmoset CYP11A1 antibody; Callithrix jacchus CYP11A1 antibody F6ZLD0 79.0%
ARP51905 White-tufted-ear marmoset CYP11A1 antibody; Callithrix jacchus CYP11A1 antibody F7HGJ9 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas204309_at721_B_lymphoblasts4.50051.930Details
BioGPS Gene Atlas204309_atAdipocyte3.60051.930Details
BioGPS Gene Atlas204309_atAdrenalCortex1193.00051.930Details
BioGPS Gene Atlas204309_atAdrenalgland1978.85051.930Details
BioGPS Gene Atlas204309_atAmygdala3.85051.930Details
BioGPS Gene Atlas204309_atAppendix3.65051.930Details
BioGPS Gene Atlas204309_atAtrioventricularNode2.75051.930Details
BioGPS Gene Atlas204309_atBDCA4+_DentriticCells4.00051.930Details
BioGPS Gene Atlas204309_atBonemarrow3.55051.930Details
BioGPS Gene Atlas204309_atBronchialEpithelialCells3.60051.930Details
BioGPS Gene Atlas204309_atCD105+_Endothelial3.70051.930Details
BioGPS Gene Atlas204309_atCD14+_Monocytes3.90051.930Details
BioGPS Gene Atlas204309_atCD19+_BCells(neg._sel.)3.90051.930Details
BioGPS Gene Atlas204309_atCD33+_Myeloid4.65051.930Details
BioGPS Gene Atlas204309_atCD34+4.60051.930Details
BioGPS Gene Atlas204309_atCD4+_Tcells4.00051.930Details
BioGPS Gene Atlas204309_atCD56+_NKCells4.35051.930Details
BioGPS Gene Atlas204309_atCD71+_EarlyErythroid3.45051.930Details
BioGPS Gene Atlas204309_atCD8+_Tcells3.50051.930Details
BioGPS Gene Atlas204309_atCardiacMyocytes4.70051.930Details
BioGPS Gene Atlas204309_atCaudatenucleus3.25051.930Details
BioGPS Gene Atlas204309_atCerebellum2.90051.930Details
BioGPS Gene Atlas204309_atCerebellumPeduncles4.10051.930Details
BioGPS Gene Atlas204309_atCiliaryGanglion2.55051.930Details
BioGPS Gene Atlas204309_atCingulateCortex3.70051.930Details
BioGPS Gene Atlas204309_atColorectaladenocarcinoma3.65051.930Details
BioGPS Gene Atlas204309_atDorsalRootGanglion2.75051.930Details
BioGPS Gene Atlas204309_atFetalThyroid3.55051.930Details
BioGPS Gene Atlas204309_atFetalbrain3.60051.930Details
BioGPS Gene Atlas204309_atFetalliver3.15051.930Details
BioGPS Gene Atlas204309_atFetallung3.00051.930Details
BioGPS Gene Atlas204309_atGlobusPallidus2.65051.930Details
BioGPS Gene Atlas204309_atHeart4.65051.930Details
BioGPS Gene Atlas204309_atHypothalamus3.95051.930Details
BioGPS Gene Atlas204309_atKidney2.90051.930Details
BioGPS Gene Atlas204309_atLeukemia_chronicMyelogenousK-5623.30051.930Details
BioGPS Gene Atlas204309_atLeukemia_promyelocytic-HL-603.20051.930Details
BioGPS Gene Atlas204309_atLeukemialymphoblastic(MOLT-4)2.90051.930Details
BioGPS Gene Atlas204309_atLiver4.80051.930Details
BioGPS Gene Atlas204309_atLung4.00051.930Details
BioGPS Gene Atlas204309_atLymphnode3.15051.930Details
BioGPS Gene Atlas204309_atLymphoma_burkitts(Daudi)4.60051.930Details
BioGPS Gene Atlas204309_atLymphoma_burkitts(Raji)5.10051.930Details
BioGPS Gene Atlas204309_atMedullaOblongata3.35051.930Details
BioGPS Gene Atlas204309_atOccipitalLobe3.25051.930Details
BioGPS Gene Atlas204309_atOlfactoryBulb2.85051.930Details
BioGPS Gene Atlas204309_atOvary5.90051.930Details
BioGPS Gene Atlas204309_atPancreas2.95051.930Details
BioGPS Gene Atlas204309_atPancreaticIslet3.90051.930Details
BioGPS Gene Atlas204309_atParietalLobe3.85051.930Details
BioGPS Gene Atlas204309_atPituitary4.25051.930Details
BioGPS Gene Atlas204309_atPlacenta1030.40051.930Details
BioGPS Gene Atlas204309_atPons3.45051.930Details
BioGPS Gene Atlas204309_atPrefrontalCortex4.55051.930Details
BioGPS Gene Atlas204309_atProstate4.25051.930Details
BioGPS Gene Atlas204309_atSalivarygland2.90051.930Details
BioGPS Gene Atlas204309_atSkeletalMuscle4.25051.930Details
BioGPS Gene Atlas204309_atSkin4.00051.930Details
BioGPS Gene Atlas204309_atSmoothMuscle4.15051.930Details
BioGPS Gene Atlas204309_atSpinalcord3.90051.930Details
BioGPS Gene Atlas204309_atSubthalamicNucleus3.30051.930Details
BioGPS Gene Atlas204309_atSuperiorCervicalGanglion4.10051.930Details
BioGPS Gene Atlas204309_atTemporalLobe3.35051.930Details
BioGPS Gene Atlas204309_atTestis14.40051.930Details
BioGPS Gene Atlas204309_atTestisGermCell15.05051.930Details
BioGPS Gene Atlas204309_atTestisIntersitial6.60051.930Details
BioGPS Gene Atlas204309_atTestisLeydigCell23.80051.930Details
BioGPS Gene Atlas204309_atTestisSeminiferousTubule6.70051.930Details
BioGPS Gene Atlas204309_atThalamus3.70051.930Details
BioGPS Gene Atlas204309_atThymus2.90051.930Details
BioGPS Gene Atlas204309_atThyroid4.60051.930Details
BioGPS Gene Atlas204309_atTongue3.55051.930Details
BioGPS Gene Atlas204309_atTonsil3.85051.930Details
BioGPS Gene Atlas204309_atTrachea3.10051.930Details
BioGPS Gene Atlas204309_atTrigeminalGanglion3.65051.930Details
BioGPS Gene Atlas204309_atUterus2.95051.930Details
BioGPS Gene Atlas204309_atUterusCorpus3.25051.930Details
BioGPS Gene Atlas204309_atWholeBlood4.00051.930Details
BioGPS Gene Atlas204309_atWholebrain3.05051.930Details
BioGPS Gene Atlas204309_atcolon3.70051.930Details
BioGPS Gene Atlas204309_atpineal_day4.58051.930Details
BioGPS Gene Atlas204309_atpineal_night4.46051.930Details
BioGPS Gene Atlas204309_atretina4.37551.930Details
BioGPS Gene Atlas204309_atsmall_intestine3.50051.930Details
BioGPS NCI60204309_at7863.8324.690Details
BioGPS NCI60204309_atA1723.6164.690Details
BioGPS NCI60204309_atA2043.7024.690Details
BioGPS NCI60204309_atA3613.7664.690Details
BioGPS NCI60204309_atA4983.7414.690Details
BioGPS NCI60204309_atA5493.7934.690Details
BioGPS NCI60204309_atACC33.8804.690Details
BioGPS NCI60204309_atACHN3.5714.690Details
BioGPS NCI60204309_atALVA313.9044.690Details
BioGPS NCI60204309_atCAKI13.8444.690Details
BioGPS NCI60204309_atCCRT CEM4.0844.690Details
BioGPS NCI60204309_atCOLO2053.7404.690Details
BioGPS NCI60204309_atDLD13.6944.690Details
BioGPS NCI60204309_atDU1453.6084.690Details
BioGPS NCI60204309_atEKVX3.6524.690Details
BioGPS NCI60204309_atGM1333.8384.690Details
BioGPS NCI60204309_atGM16003.8964.690Details
BioGPS NCI60204309_atGM23133.8044.690Details
BioGPS NCI60204309_atGM23453.7714.690Details
BioGPS NCI60204309_atGM24933.9074.690Details
BioGPS NCI60204309_atGM974.0854.690Details
BioGPS NCI60204309_atHCC29983.4924.690Details
BioGPS NCI60204309_atHCT1163.7134.690Details
BioGPS NCI60204309_atHCT153.5794.690Details
BioGPS NCI60204309_atHEK 293 T-rex3.7924.690Details
BioGPS NCI60204309_atHEK 293T3.7364.690Details
BioGPS NCI60204309_atHEK2933.7234.690Details
BioGPS NCI60204309_atHELA16.0634.690Details
BioGPS NCI60204309_atHEPG23.7304.690Details
BioGPS NCI60204309_atHL603.8084.690Details
BioGPS NCI60204309_atHOP623.7474.690Details
BioGPS NCI60204309_atHOP923.6734.690Details
BioGPS NCI60204309_atHS578T3.6974.690Details
BioGPS NCI60204309_atHSG4.4864.690Details
BioGPS NCI60204309_atHT10803.7204.690Details
BioGPS NCI60204309_atHT293.9464.690Details
BioGPS NCI60204309_atIGROV13.7104.690Details
BioGPS NCI60204309_atIOSE803.7174.690Details
BioGPS NCI60204309_atJURKAT3.7364.690Details
BioGPS NCI60204309_atK5623.9374.690Details
BioGPS NCI60204309_atKM123.8704.690Details
BioGPS NCI60204309_atLN183.5884.690Details
BioGPS NCI60204309_atLNCAP92.4334.690Details
BioGPS NCI60204309_atLOX IMVI3.7364.690Details
BioGPS NCI60204309_atM143.6994.690Details
BioGPS NCI60204309_atMALME 3M3.9014.690Details
BioGPS NCI60204309_atMCF73.6394.690Details
BioGPS NCI60204309_atMD MB2313.7714.690Details
BioGPS NCI60204309_atMDA MB4353.9444.690Details
BioGPS NCI60204309_atMOLT43.8114.690Details
BioGPS NCI60204309_atNCI 4603.8224.690Details
BioGPS NCI60204309_atNCI H2263.8134.690Details
BioGPS NCI60204309_atNCI H233.7364.690Details
BioGPS NCI60204309_atNCI H322M3.7464.690Details
BioGPS NCI60204309_atNCVADR RES3.6014.690Details
BioGPS NCI60204309_atOVCAR33.8654.690Details
BioGPS NCI60204309_atOVCAR43.7274.690Details
BioGPS NCI60204309_atOVCAR53.6964.690Details
BioGPS NCI60204309_atOVCAR83.5804.690Details
BioGPS NCI60204309_atPANC13.7854.690Details
BioGPS NCI60204309_atRL73.7924.690Details
BioGPS NCI60204309_atRPMI 82263.7804.690Details
BioGPS NCI60204309_atRS118463.8684.690Details
BioGPS NCI60204309_atRXF3933.7224.690Details
BioGPS NCI60204309_atSAOS23.7804.690Details
BioGPS NCI60204309_atSF2683.7434.690Details
BioGPS NCI60204309_atSF2953.6904.690Details
BioGPS NCI60204309_atSF5393.5944.690Details
BioGPS NCI60204309_atSHSYSY+RA3.6554.690Details
BioGPS NCI60204309_atSHSYSY-RA3.7054.690Details
BioGPS NCI60204309_atSKMEL23.7304.690Details
BioGPS NCI60204309_atSKMEL283.7434.690Details
BioGPS NCI60204309_atSKMEL53.6484.690Details
BioGPS NCI60204309_atSKOV33.8394.690Details
BioGPS NCI60204309_atSN12C3.7154.690Details
BioGPS NCI60204309_atSNB193.5974.690Details
BioGPS NCI60204309_atSNB753.7284.690Details
BioGPS NCI60204309_atSR3.7794.690Details
BioGPS NCI60204309_atSW6203.7534.690Details
BioGPS NCI60204309_atT243.8254.690Details
BioGPS NCI60204309_atT3M43.8634.690Details
BioGPS NCI60204309_atTK103.7344.690Details
BioGPS NCI60204309_atU1183.6754.690Details
BioGPS NCI60204309_atU1383.5924.690Details
BioGPS NCI60204309_atU20S3.6524.690Details
BioGPS NCI60204309_atU2513.6984.690Details
BioGPS NCI60204309_atU873.6734.690Details
BioGPS NCI60204309_atUACC2573.6994.690Details
BioGPS NCI60204309_atUACC623.7734.690Details
BioGPS NCI60204309_atUO313.6544.690Details
BioGPS NCI60204309_atZR75_13.8134.690Details
BioGPS NCI60204309_atastrocytes3.7474.690Details
BioGPS NCI60204309_athuh-73.8284.690Details