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Gene ID: 3579 | CXCR2 Antibody Resource


CXCR2 Antibody Resource
Gene Full Name: 
chemokine (C-X-C motif) receptor 2
Uniprot: 
P25025
Protein Name: 
C-X-C chemokine receptor type 2
Nucleotide: 
NM_001168298
Alias: 
CD182;IL8R2;IL8RA;IL8RB;CMKAR2;CDw128b;
Ensembl: 
ENSG00000180871
Location: 
2q35
HPRD: 
00907
NCBI Gene: 
3579
MIM: 
146928

Summary: 
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]
Function: 
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular location: 
Cell membrane; Multi-pass membrane protein.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP41956_P050 IL8RB antibody - N-terminal region (ARP41956_P050) Polyclonal Human WB 50ug $289 Details
Monoclonal Antibody OASA01427 CXCR2 Antibody (OASA01427) Human FC 100 Tests $395 Details
Monoclonal Antibody OASA01428 CXCR2 Antibody (OASA01428) Human FC 25 Tests $130 Details
DNA/cDNA/RNA ANA10343 IL8RB (Human) cDNA (1ug) 1ug $189 Details
Polyclonal Antibody OASA07550 RABBIT ANTI HUMAN CD182 (N-TERMINAL) Antibody IHC-FFPE 50ug $600 Details
Protein Lysate APL10343 IL8RB Protein Lysate (GST tagged) (Expressed in bacteria) (200ug) 200ug $219 Details
Polyclonal Antibody OAEB02582 Cxcr2 Antibody - N Terminus (OAEB02582) Mouse WB 100 ug $289 Details
Polyclonal Antibody OAAF01126 CXCR2 Antibody (OAAF01126) Polyclonal Human, Mouse IF, ELISA 100 ug $229 Details
Polyclonal Antibody OAAF00235 CXCR2 (Phospho-Ser347) Antibody (OAAF00235) Polyclonal Human, Mouse WB, IHC, IF, ELISA 100 ug $229 Details

Show all CXCR2 antibodies


Product Images
IL8RB antibody - N-terminal region (ARP41956_P050) in Human  cystic fibrosis epitheial cells using Western Blot

Sample Type: Human cystic fibrosis epitheial

CXCR2 (Phospho-Ser347) Antibody (OAAF00235) in 3T3 cells using Western Blot

Sample Type: 3T3

CXCR2 (Phospho-Ser347) Antibody (OAAF00235) in Human breast carcinoma cells using Immunohistochemistry

Sample Type: Human breast carcinoma

CXCR2 Antibody (OAAF01126) in HepG2 cells using Immunofluorescence

Sample Type: HepG2

Cxcr2 Antibody - N Terminus (OAEB02582) in Mouse Colon cells using Western Blot

Sample Type: Mouse Colon


CXCR2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP41956 Chimpanzee CXCR2 antibody; Pan troglodytes CXCR2 antibody H2QJE1 100.0%
ARP41956 Chimpanzee CXCR2 antibody; Pan troglodytes CXCR2 antibody Q28807 100.0%
ARP41956 Human CXCR2 antibody; Homo sapiens CXCR2 antibody C9J1J7 100.0%
ARP41956 Human CXCR2 antibody; Homo sapiens CXCR2 antibody C9J2F9 100.0%
ARP41956 Human CXCR2 antibody; Homo sapiens CXCR2 antibody C9JG19 100.0%
ARP41956 Human CXCR2 antibody; Homo sapiens CXCR2 antibody C9JW47 100.0%
ARP41956 Human CXCR2 antibody; Homo sapiens CXCR2 antibody P25025 100.0%
ARP41956 Lowland gorilla CXCR2 antibody; Gorilla gorilla gorilla CXCR2 antibody Q28422 92.0%
ARP41956 Sumatran orangutan CXCR2 antibody; Pongo abelii CXCR2 antibody H2P8J7 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207008_at721_B_lymphoblasts14.30071.020Details
BioGPS Gene Atlas207008_atAdipocyte13.90071.020Details
BioGPS Gene Atlas207008_atAdrenalCortex23.10071.020Details
BioGPS Gene Atlas207008_atAdrenalgland13.70071.020Details
BioGPS Gene Atlas207008_atAmygdala10.90071.020Details
BioGPS Gene Atlas207008_atAppendix25.10071.020Details
BioGPS Gene Atlas207008_atAtrioventricularNode39.50071.020Details
BioGPS Gene Atlas207008_atBDCA4+_DentriticCells17.10071.020Details
BioGPS Gene Atlas207008_atBonemarrow77.70071.020Details
BioGPS Gene Atlas207008_atBronchialEpithelialCells11.75071.020Details
BioGPS Gene Atlas207008_atCD105+_Endothelial13.20071.020Details
BioGPS Gene Atlas207008_atCD14+_Monocytes59.80071.020Details
BioGPS Gene Atlas207008_atCD19+_BCells(neg._sel.)13.85071.020Details
BioGPS Gene Atlas207008_atCD33+_Myeloid31.90071.020Details
BioGPS Gene Atlas207008_atCD34+15.10071.020Details
BioGPS Gene Atlas207008_atCD4+_Tcells13.10071.020Details
BioGPS Gene Atlas207008_atCD56+_NKCells160.85071.020Details
BioGPS Gene Atlas207008_atCD71+_EarlyErythroid14.60071.020Details
BioGPS Gene Atlas207008_atCD8+_Tcells11.60071.020Details
BioGPS Gene Atlas207008_atCardiacMyocytes40.20071.020Details
BioGPS Gene Atlas207008_atCaudatenucleus27.45071.020Details
BioGPS Gene Atlas207008_atCerebellum11.90071.020Details
BioGPS Gene Atlas207008_atCerebellumPeduncles23.65071.020Details
BioGPS Gene Atlas207008_atCiliaryGanglion35.15071.020Details
BioGPS Gene Atlas207008_atCingulateCortex20.30071.020Details
BioGPS Gene Atlas207008_atColorectaladenocarcinoma13.90071.020Details
BioGPS Gene Atlas207008_atDorsalRootGanglion16.10071.020Details
BioGPS Gene Atlas207008_atFetalThyroid14.75071.020Details
BioGPS Gene Atlas207008_atFetalbrain12.80071.020Details
BioGPS Gene Atlas207008_atFetalliver12.45071.020Details
BioGPS Gene Atlas207008_atFetallung10.40071.020Details
BioGPS Gene Atlas207008_atGlobusPallidus19.15071.020Details
BioGPS Gene Atlas207008_atHeart30.75071.020Details
BioGPS Gene Atlas207008_atHypothalamus12.45071.020Details
BioGPS Gene Atlas207008_atKidney15.75071.020Details
BioGPS Gene Atlas207008_atLeukemia_chronicMyelogenousK-56212.80071.020Details
BioGPS Gene Atlas207008_atLeukemia_promyelocytic-HL-6012.15071.020Details
BioGPS Gene Atlas207008_atLeukemialymphoblastic(MOLT-4)10.00071.020Details
BioGPS Gene Atlas207008_atLiver28.70071.020Details
BioGPS Gene Atlas207008_atLung15.70071.020Details
BioGPS Gene Atlas207008_atLymphnode11.40071.020Details
BioGPS Gene Atlas207008_atLymphoma_burkitts(Daudi)19.00071.020Details
BioGPS Gene Atlas207008_atLymphoma_burkitts(Raji)23.65071.020Details
BioGPS Gene Atlas207008_atMedullaOblongata16.25071.020Details
BioGPS Gene Atlas207008_atOccipitalLobe13.00071.020Details
BioGPS Gene Atlas207008_atOlfactoryBulb10.15071.020Details
BioGPS Gene Atlas207008_atOvary14.90071.020Details
BioGPS Gene Atlas207008_atPancreas13.75071.020Details
BioGPS Gene Atlas207008_atPancreaticIslet15.35071.020Details
BioGPS Gene Atlas207008_atParietalLobe19.65071.020Details
BioGPS Gene Atlas207008_atPituitary18.50071.020Details
BioGPS Gene Atlas207008_atPlacenta23.85071.020Details
BioGPS Gene Atlas207008_atPons17.60071.020Details
BioGPS Gene Atlas207008_atPrefrontalCortex16.25071.020Details
BioGPS Gene Atlas207008_atProstate14.95071.020Details
BioGPS Gene Atlas207008_atSalivarygland18.15071.020Details
BioGPS Gene Atlas207008_atSkeletalMuscle34.90071.020Details
BioGPS Gene Atlas207008_atSkin22.55071.020Details
BioGPS Gene Atlas207008_atSmoothMuscle15.95071.020Details
BioGPS Gene Atlas207008_atSpinalcord14.75071.020Details
BioGPS Gene Atlas207008_atSubthalamicNucleus16.00071.020Details
BioGPS Gene Atlas207008_atSuperiorCervicalGanglion66.80071.020Details
BioGPS Gene Atlas207008_atTemporalLobe13.95071.020Details
BioGPS Gene Atlas207008_atTestis11.55071.020Details
BioGPS Gene Atlas207008_atTestisGermCell15.05071.020Details
BioGPS Gene Atlas207008_atTestisIntersitial11.05071.020Details
BioGPS Gene Atlas207008_atTestisLeydigCell16.55071.020Details
BioGPS Gene Atlas207008_atTestisSeminiferousTubule12.15071.020Details
BioGPS Gene Atlas207008_atThalamus15.75071.020Details
BioGPS Gene Atlas207008_atThymus9.60071.020Details
BioGPS Gene Atlas207008_atThyroid13.50071.020Details
BioGPS Gene Atlas207008_atTongue20.90071.020Details
BioGPS Gene Atlas207008_atTonsil14.75071.020Details
BioGPS Gene Atlas207008_atTrachea12.85071.020Details
BioGPS Gene Atlas207008_atTrigeminalGanglion31.45071.020Details
BioGPS Gene Atlas207008_atUterus10.85071.020Details
BioGPS Gene Atlas207008_atUterusCorpus15.80071.020Details
BioGPS Gene Atlas207008_atWholeBlood4455.60071.020Details
BioGPS Gene Atlas207008_atWholebrain9.05071.020Details
BioGPS Gene Atlas207008_atcolon13.70071.020Details
BioGPS Gene Atlas207008_atpineal_day16.60071.020Details
BioGPS Gene Atlas207008_atpineal_night15.14071.020Details
BioGPS Gene Atlas207008_atretina19.22571.020Details
BioGPS Gene Atlas207008_atsmall_intestine13.30071.020Details
BioGPS NCI60207008_at78614.16514.250Details
BioGPS NCI60207008_atA1729.61314.250Details
BioGPS NCI60207008_atA20413.40314.250Details
BioGPS NCI60207008_atA36114.13814.250Details
BioGPS NCI60207008_atA49813.00014.250Details
BioGPS NCI60207008_atA54913.76514.250Details
BioGPS NCI60207008_atACC317.74714.250Details
BioGPS NCI60207008_atACHN10.17414.250Details
BioGPS NCI60207008_atALVA3128.10414.250Details
BioGPS NCI60207008_atCAKI115.70714.250Details
BioGPS NCI60207008_atCCRT CEM51.45414.250Details
BioGPS NCI60207008_atCOLO20513.33314.250Details
BioGPS NCI60207008_atDLD112.78014.250Details
BioGPS NCI60207008_atDU14512.17814.250Details
BioGPS NCI60207008_atEKVX12.14214.250Details
BioGPS NCI60207008_atGM13313.62114.250Details
BioGPS NCI60207008_atGM160015.13214.250Details
BioGPS NCI60207008_atGM231313.64014.250Details
BioGPS NCI60207008_atGM234513.09214.250Details
BioGPS NCI60207008_atGM249316.22314.250Details
BioGPS NCI60207008_atGM9719.77814.250Details
BioGPS NCI60207008_atHCC299811.15614.250Details
BioGPS NCI60207008_atHCT11613.54314.250Details
BioGPS NCI60207008_atHCT159.72214.250Details
BioGPS NCI60207008_atHEK 293 T-rex16.75014.250Details
BioGPS NCI60207008_atHEK 293T11.90514.250Details
BioGPS NCI60207008_atHEK29311.62314.250Details
BioGPS NCI60207008_atHELA10.25514.250Details
BioGPS NCI60207008_atHEPG213.19714.250Details
BioGPS NCI60207008_atHL6020.19614.250Details
BioGPS NCI60207008_atHOP6213.33214.250Details
BioGPS NCI60207008_atHOP9211.24914.250Details
BioGPS NCI60207008_atHS578T13.23714.250Details
BioGPS NCI60207008_atHSG12.40114.250Details
BioGPS NCI60207008_atHT108012.88614.250Details
BioGPS NCI60207008_atHT2918.59414.250Details
BioGPS NCI60207008_atIGROV112.76714.250Details
BioGPS NCI60207008_atIOSE8013.17014.250Details
BioGPS NCI60207008_atJURKAT13.10714.250Details
BioGPS NCI60207008_atK56237.96014.250Details
BioGPS NCI60207008_atKM1217.69914.250Details
BioGPS NCI60207008_atLN188.91214.250Details
BioGPS NCI60207008_atLNCAP13.30514.250Details
BioGPS NCI60207008_atLOX IMVI13.01414.250Details
BioGPS NCI60207008_atM1413.04914.250Details
BioGPS NCI60207008_atMALME 3M24.16614.250Details
BioGPS NCI60207008_atMCF711.21914.250Details
BioGPS NCI60207008_atMD MB23114.27514.250Details
BioGPS NCI60207008_atMDA MB43522.22014.250Details
BioGPS NCI60207008_atMOLT416.24414.250Details
BioGPS NCI60207008_atNCI 46013.77914.250Details
BioGPS NCI60207008_atNCI H22616.87414.250Details
BioGPS NCI60207008_atNCI H2313.29314.250Details
BioGPS NCI60207008_atNCI H322M13.00414.250Details
BioGPS NCI60207008_atNCVADR RES10.21714.250Details
BioGPS NCI60207008_atOVCAR317.40814.250Details
BioGPS NCI60207008_atOVCAR413.10114.250Details
BioGPS NCI60207008_atOVCAR511.35114.250Details
BioGPS NCI60207008_atOVCAR89.45514.250Details
BioGPS NCI60207008_atPANC114.47014.250Details
BioGPS NCI60207008_atRL714.27914.250Details
BioGPS NCI60207008_atRPMI 822616.19014.250Details
BioGPS NCI60207008_atRS1184617.97514.250Details
BioGPS NCI60207008_atRXF39313.03514.250Details
BioGPS NCI60207008_atSAOS213.27514.250Details
BioGPS NCI60207008_atSF26813.00114.250Details
BioGPS NCI60207008_atSF29512.25214.250Details
BioGPS NCI60207008_atSF5399.97614.250Details
BioGPS NCI60207008_atSHSYSY+RA12.65614.250Details
BioGPS NCI60207008_atSHSYSY-RA12.29814.250Details
BioGPS NCI60207008_atSKMEL213.04614.250Details
BioGPS NCI60207008_atSKMEL2813.16814.250Details
BioGPS NCI60207008_atSKMEL511.52314.250Details
BioGPS NCI60207008_atSKOV314.97314.250Details
BioGPS NCI60207008_atSN12C12.70114.250Details
BioGPS NCI60207008_atSNB199.87114.250Details
BioGPS NCI60207008_atSNB7513.06314.250Details
BioGPS NCI60207008_atSR20.78114.250Details
BioGPS NCI60207008_atSW62014.46514.250Details
BioGPS NCI60207008_atT2414.34514.250Details
BioGPS NCI60207008_atT3M419.17514.250Details
BioGPS NCI60207008_atTK1013.02614.250Details
BioGPS NCI60207008_atU11811.15914.250Details
BioGPS NCI60207008_atU1388.79514.250Details
BioGPS NCI60207008_atU20S12.09414.250Details
BioGPS NCI60207008_atU25112.80914.250Details
BioGPS NCI60207008_atU8710.21314.250Details
BioGPS NCI60207008_atUACC25712.48314.250Details
BioGPS NCI60207008_atUACC6214.24714.250Details
BioGPS NCI60207008_atUO3110.49114.250Details
BioGPS NCI60207008_atZR75_114.64814.250Details
BioGPS NCI60207008_atastrocytes12.76414.250Details
BioGPS NCI60207008_athuh-714.76314.250Details