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Gene ID: 1514 | CTSL Antibody Resource


CTSL Antibody Resource
Gene Full Name: 
cathepsin L
Uniprot: 
P07711
Protein Name: 
cathepsin L1
Nucleotide: 
NM_001912
Alias: 
MEP;CATL;CTSL1;
Ensembl: 
ENSG00000135047
Location: 
9q21.33
HPRD: 
00293
NCBI Gene: 
1514
MIM: 
116880

Summary: 
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
Function: 
Important for the overall degradation of proteins in lysosomes.
Subcellular location: 
Lysosome.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP63239_P050 CTSL1 antibody - C-terminal region (ARP63239_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP63240_P050 CTSL1 Antibody (ARP63240_P050) Polyclonal Bovine, Dog, Horse, Human, Pig, Rabbit, Sheep Not tested 50 ug $125 Details

Show all CTSL antibodies


Product Images
CTSL1 antibody - C-terminal region (ARP63239_P050) in Human HT1080 cells using Western Blot

Sample Type: Human HT1080


CTSL Protocols
Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP61285 Atlantic halibut CTSL antibody; Hippoglossus hippoglossus CTSL antibody A0FJU7 86.0%
ARP61285 Bovine CTSL antibody; Bos taurus CTSL antibody P25975 93.0%
ARP63240 Bovine CTSL antibody; Bos taurus CTSL antibody P25975 85.0%
ARP61284 Cat CTSL antibody; Felis catus CTSL antibody P25773 100.0%
ARP61285 Chicken CTSL antibody; Gallus gallus CTSL antibody P09648 86.0%
ARP60949 Chicken CTSL antibody; Gallus gallus CTSL antibody P09648 80.0%
ARP61285 Dog CTSL antibody; Canis familiaris CTSL antibody Q9GL24 93.0%
ARP63239 Green monkey CTSL antibody; Chlorocebus aethiops CTSL antibody Q9GKL8 100.0%
ARP61285 Green monkey CTSL antibody; Chlorocebus aethiops CTSL antibody Q9GKL8 93.0%
ARP61284 Green monkey CTSL antibody; Chlorocebus aethiops CTSL antibody Q9GKL8 86.0%
ARP63240 Green monkey CTSL antibody; Chlorocebus aethiops CTSL antibody Q9GKL8 86.0%
ARP63239 Human CTSL antibody; Homo sapiens CTSL antibody Q9HBQ7 100.0%
ARP63239 Human CTSL antibody; Homo sapiens CTSL antibody P07711 100.0%
ARP63240 Human CTSL antibody; Homo sapiens CTSL antibody P07711 100.0%
ARP61285 Human CTSL antibody; Homo sapiens CTSL antibody P07711 93.0%
ARP61284 Human CTSL antibody; Homo sapiens CTSL antibody Q9HBQ7 79.0%
ARP61284 Human CTSL antibody; Homo sapiens CTSL antibody P07711 79.0%
ARP61285 Medaka fish CTSL antibody; Oryzias latipes CTSL antibody Q6F6A1 86.0%
ARP61285 Medaka fish CTSL antibody; Oryzias latipes CTSL antibody H2N2S1 86.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q3UHZ4 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q3UWH6 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q543M3 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q6LAF5 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q9D0C0 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody P06797 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q3TNC8 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q3TVJ1 79.0%
ARP61284 Mouse CTSL antibody; Mus musculus CTSL antibody Q3U5U9 79.0%
ARP63240 Pig CTSL antibody; Sus scrofa CTSL antibody Q28944 85.0%
ARP61284 Rat CTSL antibody; Rattus norvegicus CTSL antibody P07154 79.0%
ARP63239 Rhesus macaque CTSL antibody; Macaca mulatta CTSL antibody F6VSF4 100.0%
ARP61285 Rhesus macaque CTSL antibody; Macaca mulatta CTSL antibody F6VSF4 93.0%
ARP61284 Rhesus macaque CTSL antibody; Macaca mulatta CTSL antibody F6VSF4 86.0%
ARP63240 Rhesus macaque CTSL antibody; Macaca mulatta CTSL antibody F6VSF4 86.0%
ARP61285 Sheep CTSL antibody; Ovis aries CTSL antibody Q10991 93.0%
ARP63239 Sumatran orangutan CTSL antibody; Pongo abelii CTSL antibody H2PSK9 100.0%
ARP63240 Sumatran orangutan CTSL antibody; Pongo abelii CTSL antibody H2PSK9 100.0%
ARP61285 Sumatran orangutan CTSL antibody; Pongo abelii CTSL antibody H2PSK9 93.0%
ARP61284 Sumatran orangutan CTSL antibody; Pongo abelii CTSL antibody H2PSK9 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas202087_s_at721_B_lymphoblasts42.000147.500Details
BioGPS Gene Atlas202087_s_atAdipocyte420.500147.500Details
BioGPS Gene Atlas202087_s_atAdrenalCortex89.450147.500Details
BioGPS Gene Atlas202087_s_atAdrenalgland72.200147.500Details
BioGPS Gene Atlas202087_s_atAmygdala69.450147.500Details
BioGPS Gene Atlas202087_s_atAppendix77.850147.500Details
BioGPS Gene Atlas202087_s_atAtrioventricularNode56.050147.500Details
BioGPS Gene Atlas202087_s_atBDCA4+_DentriticCells28.200147.500Details
BioGPS Gene Atlas202087_s_atBonemarrow93.600147.500Details
BioGPS Gene Atlas202087_s_atBronchialEpithelialCells210.400147.500Details
BioGPS Gene Atlas202087_s_atCD105+_Endothelial314.600147.500Details
BioGPS Gene Atlas202087_s_atCD14+_Monocytes93.800147.500Details
BioGPS Gene Atlas202087_s_atCD19+_BCells(neg._sel.)31.200147.500Details
BioGPS Gene Atlas202087_s_atCD33+_Myeloid57.950147.500Details
BioGPS Gene Atlas202087_s_atCD34+64.500147.500Details
BioGPS Gene Atlas202087_s_atCD4+_Tcells47.050147.500Details
BioGPS Gene Atlas202087_s_atCD56+_NKCells70.850147.500Details
BioGPS Gene Atlas202087_s_atCD71+_EarlyErythroid695.150147.500Details
BioGPS Gene Atlas202087_s_atCD8+_Tcells34.800147.500Details
BioGPS Gene Atlas202087_s_atCardiacMyocytes167.500147.500Details
BioGPS Gene Atlas202087_s_atCaudatenucleus64.250147.500Details
BioGPS Gene Atlas202087_s_atCerebellum35.550147.500Details
BioGPS Gene Atlas202087_s_atCerebellumPeduncles80.750147.500Details
BioGPS Gene Atlas202087_s_atCiliaryGanglion86.150147.500Details
BioGPS Gene Atlas202087_s_atCingulateCortex81.000147.500Details
BioGPS Gene Atlas202087_s_atColorectaladenocarcinoma52.700147.500Details
BioGPS Gene Atlas202087_s_atDorsalRootGanglion52.550147.500Details
BioGPS Gene Atlas202087_s_atFetalThyroid183.550147.500Details
BioGPS Gene Atlas202087_s_atFetalbrain53.100147.500Details
BioGPS Gene Atlas202087_s_atFetalliver159.950147.500Details
BioGPS Gene Atlas202087_s_atFetallung348.950147.500Details
BioGPS Gene Atlas202087_s_atGlobusPallidus43.700147.500Details
BioGPS Gene Atlas202087_s_atHeart103.950147.500Details
BioGPS Gene Atlas202087_s_atHypothalamus160.600147.500Details
BioGPS Gene Atlas202087_s_atKidney198.800147.500Details
BioGPS Gene Atlas202087_s_atLeukemia_chronicMyelogenousK-562261.250147.500Details
BioGPS Gene Atlas202087_s_atLeukemia_promyelocytic-HL-6037.700147.500Details
BioGPS Gene Atlas202087_s_atLeukemialymphoblastic(MOLT-4)33.300147.500Details
BioGPS Gene Atlas202087_s_atLiver135.650147.500Details
BioGPS Gene Atlas202087_s_atLung229.850147.500Details
BioGPS Gene Atlas202087_s_atLymphnode163.350147.500Details
BioGPS Gene Atlas202087_s_atLymphoma_burkitts(Daudi)55.150147.500Details
BioGPS Gene Atlas202087_s_atLymphoma_burkitts(Raji)69.300147.500Details
BioGPS Gene Atlas202087_s_atMedullaOblongata60.800147.500Details
BioGPS Gene Atlas202087_s_atOccipitalLobe86.750147.500Details
BioGPS Gene Atlas202087_s_atOlfactoryBulb102.200147.500Details
BioGPS Gene Atlas202087_s_atOvary80.850147.500Details
BioGPS Gene Atlas202087_s_atPancreas55.050147.500Details
BioGPS Gene Atlas202087_s_atPancreaticIslet412.450147.500Details
BioGPS Gene Atlas202087_s_atParietalLobe75.450147.500Details
BioGPS Gene Atlas202087_s_atPituitary153.300147.500Details
BioGPS Gene Atlas202087_s_atPlacenta1212.750147.500Details
BioGPS Gene Atlas202087_s_atPons113.800147.500Details
BioGPS Gene Atlas202087_s_atPrefrontalCortex141.900147.500Details
BioGPS Gene Atlas202087_s_atProstate177.250147.500Details
BioGPS Gene Atlas202087_s_atSalivarygland87.950147.500Details
BioGPS Gene Atlas202087_s_atSkeletalMuscle77.100147.500Details
BioGPS Gene Atlas202087_s_atSkin50.900147.500Details
BioGPS Gene Atlas202087_s_atSmoothMuscle279.100147.500Details
BioGPS Gene Atlas202087_s_atSpinalcord120.500147.500Details
BioGPS Gene Atlas202087_s_atSubthalamicNucleus55.450147.500Details
BioGPS Gene Atlas202087_s_atSuperiorCervicalGanglion59.950147.500Details
BioGPS Gene Atlas202087_s_atTemporalLobe54.400147.500Details
BioGPS Gene Atlas202087_s_atTestis148.250147.500Details
BioGPS Gene Atlas202087_s_atTestisGermCell184.800147.500Details
BioGPS Gene Atlas202087_s_atTestisIntersitial173.950147.500Details
BioGPS Gene Atlas202087_s_atTestisLeydigCell157.250147.500Details
BioGPS Gene Atlas202087_s_atTestisSeminiferousTubule138.300147.500Details
BioGPS Gene Atlas202087_s_atThalamus89.300147.500Details
BioGPS Gene Atlas202087_s_atThymus55.900147.500Details
BioGPS Gene Atlas202087_s_atThyroid283.200147.500Details
BioGPS Gene Atlas202087_s_atTongue55.750147.500Details
BioGPS Gene Atlas202087_s_atTonsil65.150147.500Details
BioGPS Gene Atlas202087_s_atTrachea57.800147.500Details
BioGPS Gene Atlas202087_s_atTrigeminalGanglion156.200147.500Details
BioGPS Gene Atlas202087_s_atUterus132.850147.500Details
BioGPS Gene Atlas202087_s_atUterusCorpus414.500147.500Details
BioGPS Gene Atlas202087_s_atWholeBlood39.050147.500Details
BioGPS Gene Atlas202087_s_atWholebrain124.550147.500Details
BioGPS Gene Atlas202087_s_atcolon177.800147.500Details
BioGPS Gene Atlas202087_s_atpineal_day135.660147.500Details
BioGPS Gene Atlas202087_s_atpineal_night175.760147.500Details
BioGPS Gene Atlas202087_s_atretina360.950147.500Details
BioGPS Gene Atlas202087_s_atsmall_intestine138.500147.500Details
BioGPS NCI60202087_s_at7861168.1091573.150Details
BioGPS NCI60202087_s_atA1724116.2911573.150Details
BioGPS NCI60202087_s_atA2041011.3861573.150Details
BioGPS NCI60202087_s_atA3618222.1441573.150Details
BioGPS NCI60202087_s_atA4983889.6001573.150Details
BioGPS NCI60202087_s_atA5492592.0991573.150Details
BioGPS NCI60202087_s_atACC3666.2961573.150Details
BioGPS NCI60202087_s_atACHN665.5351573.150Details
BioGPS NCI60202087_s_atALVA31599.5001573.150Details
BioGPS NCI60202087_s_atCAKI1725.4761573.150Details
BioGPS NCI60202087_s_atCCRT CEM29.3961573.150Details
BioGPS NCI60202087_s_atCOLO20527.0991573.150Details
BioGPS NCI60202087_s_atDLD1720.7581573.150Details
BioGPS NCI60202087_s_atDU1452471.3081573.150Details
BioGPS NCI60202087_s_atEKVX1437.8811573.150Details
BioGPS NCI60202087_s_atGM1331992.2521573.150Details
BioGPS NCI60202087_s_atGM16001155.7411573.150Details
BioGPS NCI60202087_s_atGM23133589.7861573.150Details
BioGPS NCI60202087_s_atGM23452617.0111573.150Details
BioGPS NCI60202087_s_atGM24933111.9381573.150Details
BioGPS NCI60202087_s_atGM973870.0991573.150Details
BioGPS NCI60202087_s_atHCC299865.5501573.150Details
BioGPS NCI60202087_s_atHCT116603.3861573.150Details
BioGPS NCI60202087_s_atHCT15388.3391573.150Details
BioGPS NCI60202087_s_atHEK 293 T-rex738.8941573.150Details
BioGPS NCI60202087_s_atHEK 293T497.6131573.150Details
BioGPS NCI60202087_s_atHEK293901.1781573.150Details
BioGPS NCI60202087_s_atHELA1550.0391573.150Details
BioGPS NCI60202087_s_atHEPG2363.9061573.150Details
BioGPS NCI60202087_s_atHL6030.0591573.150Details
BioGPS NCI60202087_s_atHOP62899.4551573.150Details
BioGPS NCI60202087_s_atHOP92460.4121573.150Details
BioGPS NCI60202087_s_atHS578T1757.4221573.150Details
BioGPS NCI60202087_s_atHSG653.5621573.150Details
BioGPS NCI60202087_s_atHT1080746.9011573.150Details
BioGPS NCI60202087_s_atHT29110.0341573.150Details
BioGPS NCI60202087_s_atIGROV11008.6141573.150Details
BioGPS NCI60202087_s_atIOSE80903.6951573.150Details
BioGPS NCI60202087_s_atJURKAT28.0671573.150Details
BioGPS NCI60202087_s_atK562758.9391573.150Details
BioGPS NCI60202087_s_atKM1227.6131573.150Details
BioGPS NCI60202087_s_atLN18464.8511573.150Details
BioGPS NCI60202087_s_atLNCAP728.0401573.150Details
BioGPS NCI60202087_s_atLOX IMVI1316.9831573.150Details
BioGPS NCI60202087_s_atM14303.1331573.150Details
BioGPS NCI60202087_s_atMALME 3M1422.9731573.150Details
BioGPS NCI60202087_s_atMCF71173.2721573.150Details
BioGPS NCI60202087_s_atMD MB231807.3431573.150Details
BioGPS NCI60202087_s_atMDA MB435179.8751573.150Details
BioGPS NCI60202087_s_atMOLT427.4731573.150Details
BioGPS NCI60202087_s_atNCI 4609161.7101573.150Details
BioGPS NCI60202087_s_atNCI H2261394.3041573.150Details
BioGPS NCI60202087_s_atNCI H232636.2871573.150Details
BioGPS NCI60202087_s_atNCI H322M643.3791573.150Details
BioGPS NCI60202087_s_atNCVADR RES463.3441573.150Details
BioGPS NCI60202087_s_atOVCAR3483.9011573.150Details
BioGPS NCI60202087_s_atOVCAR4305.8451573.150Details
BioGPS NCI60202087_s_atOVCAR5662.0211573.150Details
BioGPS NCI60202087_s_atOVCAR8921.7731573.150Details
BioGPS NCI60202087_s_atPANC1401.0671573.150Details
BioGPS NCI60202087_s_atRL727.4531573.150Details
BioGPS NCI60202087_s_atRPMI 822627.3871573.150Details
BioGPS NCI60202087_s_atRS1184630.2651573.150Details
BioGPS NCI60202087_s_atRXF3931273.9501573.150Details
BioGPS NCI60202087_s_atSAOS21326.9681573.150Details
BioGPS NCI60202087_s_atSF268858.7411573.150Details
BioGPS NCI60202087_s_atSF2951714.6271573.150Details
BioGPS NCI60202087_s_atSF5392279.7781573.150Details
BioGPS NCI60202087_s_atSHSYSY+RA331.9451573.150Details
BioGPS NCI60202087_s_atSHSYSY-RA293.4561573.150Details
BioGPS NCI60202087_s_atSKMEL21280.0371573.150Details
BioGPS NCI60202087_s_atSKMEL282713.5651573.150Details
BioGPS NCI60202087_s_atSKMEL56221.0861573.150Details
BioGPS NCI60202087_s_atSKOV31264.5951573.150Details
BioGPS NCI60202087_s_atSN12C2107.9031573.150Details
BioGPS NCI60202087_s_atSNB191166.7061573.150Details
BioGPS NCI60202087_s_atSNB752257.3581573.150Details
BioGPS NCI60202087_s_atSR3068.2281573.150Details
BioGPS NCI60202087_s_atSW62027.2341573.150Details
BioGPS NCI60202087_s_atT241003.6331573.150Details
BioGPS NCI60202087_s_atT3M4929.4851573.150Details
BioGPS NCI60202087_s_atTK101120.2061573.150Details
BioGPS NCI60202087_s_atU1186217.5161573.150Details
BioGPS NCI60202087_s_atU1385777.0591573.150Details
BioGPS NCI60202087_s_atU20S801.5441573.150Details
BioGPS NCI60202087_s_atU2511523.1971573.150Details
BioGPS NCI60202087_s_atU876551.3991573.150Details
BioGPS NCI60202087_s_atUACC2572335.0971573.150Details
BioGPS NCI60202087_s_atUACC621341.0241573.150Details
BioGPS NCI60202087_s_atUO31659.8021573.150Details
BioGPS NCI60202087_s_atZR75_168.6411573.150Details
BioGPS NCI60202087_s_atastrocytes630.9951573.150Details
BioGPS NCI60202087_s_athuh-7318.5771573.150Details