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Gene ID: 8722 | CTSF Antibody Resource


CTSF Antibody Resource
Gene Full Name: 
cathepsin F
Uniprot: 
Q9UBX1
Protein Name: 
cathepsin F
Nucleotide: 
NM_003793
Alias: 
CATSF;CLN13;
Ensembl: 
ENSG00000174080
Location: 
11q13
HPRD: 
04643
NCBI Gene: 
8722
MIM: 
603539

Summary: 
Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008]
Function: 
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Subcellular location: 
Lysosome.
PTM: 
Disulfide bond;
Disease: 
Ceroid lipofuscinosis, neuronal, 13 (CLN13) [MIM:615362]: A form of neuronal ceroid lipofuscinosis characterized by adult onset of progressive cognitive decline and motor dysfunction leading to dementia and often early death. Some patients develop seizures. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB01899 CTSF Antibody (OAEB01899) Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat WB 0.1mg $289 Details
Polyclonal Antibody OAAB03579 CTSF Antibody (OAAB03579) Human WB, IHC, FC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB03580 CTSF Antibody (OAAB03580) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP64650_P050 CTSF Antibody (ARP64650_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody ARP64651_P050 CTSF Antibody (ARP64651_P050) Polyclonal Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details

Show all CTSF antibodies


Product Images
CTSF Antibody (OAAB03580) in Human Skeletal Muscle cells using Immunohistochemistry

Sample Type: Human Skeletal Muscle

CTSF Antibody (OAAB03580) in MDA-MB231 cells using Western Blot

Sample Type: MDA-MB231

CTSF Antibody (OAEB01899) in Human Ovary cells using Western Blot

Sample Type: Human Ovary


CTSF Protocols

Publications
Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP64650 Chimpanzee CTSF antibody; Pan troglodytes CTSF antibody H2Q471 100.0%
ARP64651 Chimpanzee CTSF antibody; Pan troglodytes CTSF antibody H2Q471 100.0%
ARP64651 Dog CTSF antibody; Canis familiaris CTSF antibody E2RR02 79.0%
ARP64651 European domestic ferret CTSF antibody; Mustela putorius furo CTSF antibody M3XWE6 79.0%
ARP64651 Giant panda CTSF antibody; Ailuropoda melanoleuca CTSF antibody G1LWU5 86.0%
ARP64651 Horse CTSF antibody; Equus caballus CTSF antibody F6YUR2 79.0%
ARP64650 Human CTSF antibody; Homo sapiens CTSF antibody E9PSC2 100.0%
ARP64651 Human CTSF antibody; Homo sapiens CTSF antibody E9PSC2 100.0%
ARP64650 Human CTSF antibody; Homo sapiens CTSF antibody H0YD65 100.0%
ARP64650 Human CTSF antibody; Homo sapiens CTSF antibody Q6FHS1 100.0%
ARP64651 Human CTSF antibody; Homo sapiens CTSF antibody Q6FHS1 100.0%
ARP64650 Human CTSF antibody; Homo sapiens CTSF antibody Q9UBX1 100.0%
ARP64651 Human CTSF antibody; Homo sapiens CTSF antibody Q9UBX1 100.0%
ARP64651 Human CTSF antibody; Homo sapiens CTSF antibody H0YD65 93.0%
ARP64651 Mouse CTSF antibody; Mus musculus CTSF antibody Q99KQ9 86.0%
ARP64651 Mouse CTSF antibody; Mus musculus CTSF antibody Q9ES93 86.0%
ARP64651 Mouse CTSF antibody; Mus musculus CTSF antibody Q9R013 86.0%
ARP64651 Pig CTSF antibody; Sus scrofa CTSF antibody F1RU48 79.0%
ARP64651 Rat CTSF antibody; Rattus norvegicus CTSF antibody Q499S6 86.0%
ARP64651 Small-eared galago CTSF antibody; Otolemur garnettii CTSF antibody H0WLC6 86.0%
ARP64650 Sumatran orangutan CTSF antibody; Pongo abelii CTSF antibody H2NCQ9 100.0%
ARP64651 Sumatran orangutan CTSF antibody; Pongo abelii CTSF antibody H2NCQ9 100.0%
ARP64651 Thirteen-lined ground squirrel CTSF antibody; Spermophilus tridecemlineatus CTSF antibody I3ME67 79.0%
ARP64651 White-tufted-ear marmoset CTSF antibody; Callithrix jacchus CTSF antibody U3EDA6 93.0%
ARP64651 White-tufted-ear marmoset CTSF antibody; Callithrix jacchus CTSF antibody U3EVC0 93.0%
ARP64651 White-tufted-ear marmoset CTSF antibody; Callithrix jacchus CTSF antibody F7IIX5 93.0%
ARP64651 White-tufted-ear marmoset CTSF antibody; Callithrix jacchus CTSF antibody F7IL49 93.0%
ARP64651 White-tufted-ear marmoset CTSF antibody; Callithrix jacchus CTSF antibody U3E7F4 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas203657_s_at721_B_lymphoblasts29.800148.800Details
BioGPS Gene Atlas203657_s_atAdipocyte88.850148.800Details
BioGPS Gene Atlas203657_s_atAdrenalCortex119.900148.800Details
BioGPS Gene Atlas203657_s_atAdrenalgland101.850148.800Details
BioGPS Gene Atlas203657_s_atAmygdala273.600148.800Details
BioGPS Gene Atlas203657_s_atAppendix102.400148.800Details
BioGPS Gene Atlas203657_s_atAtrioventricularNode31.500148.800Details
BioGPS Gene Atlas203657_s_atBDCA4+_DentriticCells36.300148.800Details
BioGPS Gene Atlas203657_s_atBonemarrow60.250148.800Details
BioGPS Gene Atlas203657_s_atBronchialEpithelialCells11.050148.800Details
BioGPS Gene Atlas203657_s_atCD105+_Endothelial57.250148.800Details
BioGPS Gene Atlas203657_s_atCD14+_Monocytes28.450148.800Details
BioGPS Gene Atlas203657_s_atCD19+_BCells(neg._sel.)33.000148.800Details
BioGPS Gene Atlas203657_s_atCD33+_Myeloid43.050148.800Details
BioGPS Gene Atlas203657_s_atCD34+75.400148.800Details
BioGPS Gene Atlas203657_s_atCD4+_Tcells78.350148.800Details
BioGPS Gene Atlas203657_s_atCD56+_NKCells70.200148.800Details
BioGPS Gene Atlas203657_s_atCD71+_EarlyErythroid33.600148.800Details
BioGPS Gene Atlas203657_s_atCD8+_Tcells74.500148.800Details
BioGPS Gene Atlas203657_s_atCardiacMyocytes80.750148.800Details
BioGPS Gene Atlas203657_s_atCaudatenucleus221.900148.800Details
BioGPS Gene Atlas203657_s_atCerebellum129.300148.800Details
BioGPS Gene Atlas203657_s_atCerebellumPeduncles320.150148.800Details
BioGPS Gene Atlas203657_s_atCiliaryGanglion31.600148.800Details
BioGPS Gene Atlas203657_s_atCingulateCortex176.300148.800Details
BioGPS Gene Atlas203657_s_atColorectaladenocarcinoma43.700148.800Details
BioGPS Gene Atlas203657_s_atDorsalRootGanglion57.850148.800Details
BioGPS Gene Atlas203657_s_atFetalThyroid68.100148.800Details
BioGPS Gene Atlas203657_s_atFetalbrain80.200148.800Details
BioGPS Gene Atlas203657_s_atFetalliver50.350148.800Details
BioGPS Gene Atlas203657_s_atFetallung30.750148.800Details
BioGPS Gene Atlas203657_s_atGlobusPallidus98.450148.800Details
BioGPS Gene Atlas203657_s_atHeart344.950148.800Details
BioGPS Gene Atlas203657_s_atHypothalamus260.000148.800Details
BioGPS Gene Atlas203657_s_atKidney110.250148.800Details
BioGPS Gene Atlas203657_s_atLeukemia_chronicMyelogenousK-56238.050148.800Details
BioGPS Gene Atlas203657_s_atLeukemia_promyelocytic-HL-6029.750148.800Details
BioGPS Gene Atlas203657_s_atLeukemialymphoblastic(MOLT-4)26.050148.800Details
BioGPS Gene Atlas203657_s_atLiver800.150148.800Details
BioGPS Gene Atlas203657_s_atLung333.050148.800Details
BioGPS Gene Atlas203657_s_atLymphnode44.150148.800Details
BioGPS Gene Atlas203657_s_atLymphoma_burkitts(Daudi)54.850148.800Details
BioGPS Gene Atlas203657_s_atLymphoma_burkitts(Raji)36.650148.800Details
BioGPS Gene Atlas203657_s_atMedullaOblongata131.400148.800Details
BioGPS Gene Atlas203657_s_atOccipitalLobe170.600148.800Details
BioGPS Gene Atlas203657_s_atOlfactoryBulb122.250148.800Details
BioGPS Gene Atlas203657_s_atOvary40.600148.800Details
BioGPS Gene Atlas203657_s_atPancreas33.350148.800Details
BioGPS Gene Atlas203657_s_atPancreaticIslet69.100148.800Details
BioGPS Gene Atlas203657_s_atParietalLobe140.500148.800Details
BioGPS Gene Atlas203657_s_atPituitary89.650148.800Details
BioGPS Gene Atlas203657_s_atPlacenta99.150148.800Details
BioGPS Gene Atlas203657_s_atPons102.900148.800Details
BioGPS Gene Atlas203657_s_atPrefrontalCortex228.250148.800Details
BioGPS Gene Atlas203657_s_atProstate248.750148.800Details
BioGPS Gene Atlas203657_s_atSalivarygland73.200148.800Details
BioGPS Gene Atlas203657_s_atSkeletalMuscle61.350148.800Details
BioGPS Gene Atlas203657_s_atSkin28.850148.800Details
BioGPS Gene Atlas203657_s_atSmoothMuscle60.800148.800Details
BioGPS Gene Atlas203657_s_atSpinalcord226.300148.800Details
BioGPS Gene Atlas203657_s_atSubthalamicNucleus134.700148.800Details
BioGPS Gene Atlas203657_s_atSuperiorCervicalGanglion49.350148.800Details
BioGPS Gene Atlas203657_s_atTemporalLobe106.600148.800Details
BioGPS Gene Atlas203657_s_atTestis555.250148.800Details
BioGPS Gene Atlas203657_s_atTestisGermCell294.550148.800Details
BioGPS Gene Atlas203657_s_atTestisIntersitial195.550148.800Details
BioGPS Gene Atlas203657_s_atTestisLeydigCell195.500148.800Details
BioGPS Gene Atlas203657_s_atTestisSeminiferousTubule141.600148.800Details
BioGPS Gene Atlas203657_s_atThalamus259.500148.800Details
BioGPS Gene Atlas203657_s_atThymus31.700148.800Details
BioGPS Gene Atlas203657_s_atThyroid206.400148.800Details
BioGPS Gene Atlas203657_s_atTongue53.550148.800Details
BioGPS Gene Atlas203657_s_atTonsil36.100148.800Details
BioGPS Gene Atlas203657_s_atTrachea49.900148.800Details
BioGPS Gene Atlas203657_s_atTrigeminalGanglion66.400148.800Details
BioGPS Gene Atlas203657_s_atUterus238.150148.800Details
BioGPS Gene Atlas203657_s_atUterusCorpus91.800148.800Details
BioGPS Gene Atlas203657_s_atWholeBlood20.900148.800Details
BioGPS Gene Atlas203657_s_atWholebrain490.200148.800Details
BioGPS Gene Atlas203657_s_atcolon63.500148.800Details
BioGPS Gene Atlas203657_s_atpineal_day486.380148.800Details
BioGPS Gene Atlas203657_s_atpineal_night404.240148.800Details
BioGPS Gene Atlas203657_s_atretina386.900148.800Details
BioGPS Gene Atlas203657_s_atsmall_intestine69.450148.800Details
BioGPS NCI60203657_s_at7868.78317.620Details
BioGPS NCI60203657_s_atA1726.03417.620Details
BioGPS NCI60203657_s_atA2048.62517.620Details
BioGPS NCI60203657_s_atA36126.46517.620Details
BioGPS NCI60203657_s_atA49811.75417.620Details
BioGPS NCI60203657_s_atA54924.73117.620Details
BioGPS NCI60203657_s_atACC351.66117.620Details
BioGPS NCI60203657_s_atACHN5.46417.620Details
BioGPS NCI60203657_s_atALVA318.39217.620Details
BioGPS NCI60203657_s_atCAKI19.26117.620Details
BioGPS NCI60203657_s_atCCRT CEM18.05217.620Details
BioGPS NCI60203657_s_atCOLO2058.68617.620Details
BioGPS NCI60203657_s_atDLD16.26517.620Details
BioGPS NCI60203657_s_atDU14517.50117.620Details
BioGPS NCI60203657_s_atEKVX122.02217.620Details
BioGPS NCI60203657_s_atGM1338.87417.620Details
BioGPS NCI60203657_s_atGM16009.65217.620Details
BioGPS NCI60203657_s_atGM23139.44217.620Details
BioGPS NCI60203657_s_atGM234510.58117.620Details
BioGPS NCI60203657_s_atGM24939.65717.620Details
BioGPS NCI60203657_s_atGM9713.40517.620Details
BioGPS NCI60203657_s_atHCC29988.68917.620Details
BioGPS NCI60203657_s_atHCT1165.84417.620Details
BioGPS NCI60203657_s_atHCT155.46317.620Details
BioGPS NCI60203657_s_atHEK 293 T-rex9.08217.620Details
BioGPS NCI60203657_s_atHEK 293T8.94117.620Details
BioGPS NCI60203657_s_atHEK2937.52317.620Details
BioGPS NCI60203657_s_atHELA5.46417.620Details
BioGPS NCI60203657_s_atHEPG27.65417.620Details
BioGPS NCI60203657_s_atHL608.50817.620Details
BioGPS NCI60203657_s_atHOP628.69317.620Details
BioGPS NCI60203657_s_atHOP9233.55017.620Details
BioGPS NCI60203657_s_atHS578T16.45217.620Details
BioGPS NCI60203657_s_atHSG15.42117.620Details
BioGPS NCI60203657_s_atHT10807.06617.620Details
BioGPS NCI60203657_s_atHT298.93817.620Details
BioGPS NCI60203657_s_atIGROV19.51617.620Details
BioGPS NCI60203657_s_atIOSE809.23517.620Details
BioGPS NCI60203657_s_atJURKAT8.64017.620Details
BioGPS NCI60203657_s_atK5629.86217.620Details
BioGPS NCI60203657_s_atKM128.19817.620Details
BioGPS NCI60203657_s_atLN1863.88717.620Details
BioGPS NCI60203657_s_atLNCAP21.11717.620Details
BioGPS NCI60203657_s_atLOX IMVI8.63417.620Details
BioGPS NCI60203657_s_atM1427.10117.620Details
BioGPS NCI60203657_s_atMALME 3M26.46217.620Details
BioGPS NCI60203657_s_atMCF75.92217.620Details
BioGPS NCI60203657_s_atMD MB23115.77017.620Details
BioGPS NCI60203657_s_atMDA MB435217.62317.620Details
BioGPS NCI60203657_s_atMOLT48.73817.620Details
BioGPS NCI60203657_s_atNCI 4609.47717.620Details
BioGPS NCI60203657_s_atNCI H2268.81817.620Details
BioGPS NCI60203657_s_atNCI H2317.51217.620Details
BioGPS NCI60203657_s_atNCI H322M8.66017.620Details
BioGPS NCI60203657_s_atNCVADR RES15.39517.620Details
BioGPS NCI60203657_s_atOVCAR325.00317.620Details
BioGPS NCI60203657_s_atOVCAR48.61017.620Details
BioGPS NCI60203657_s_atOVCAR58.59417.620Details
BioGPS NCI60203657_s_atOVCAR811.41617.620Details
BioGPS NCI60203657_s_atPANC134.68317.620Details
BioGPS NCI60203657_s_atRL79.33917.620Details
BioGPS NCI60203657_s_atRPMI 822618.77517.620Details
BioGPS NCI60203657_s_atRS118468.79417.620Details
BioGPS NCI60203657_s_atRXF3936.48617.620Details
BioGPS NCI60203657_s_atSAOS214.63617.620Details
BioGPS NCI60203657_s_atSF2688.79117.620Details
BioGPS NCI60203657_s_atSF29510.84317.620Details
BioGPS NCI60203657_s_atSF5398.29017.620Details
BioGPS NCI60203657_s_atSHSYSY+RA12.53917.620Details
BioGPS NCI60203657_s_atSHSYSY-RA47.88417.620Details
BioGPS NCI60203657_s_atSKMEL212.53617.620Details
BioGPS NCI60203657_s_atSKMEL2842.44717.620Details
BioGPS NCI60203657_s_atSKMEL570.18917.620Details
BioGPS NCI60203657_s_atSKOV312.09317.620Details
BioGPS NCI60203657_s_atSN12C14.92717.620Details
BioGPS NCI60203657_s_atSNB1910.55417.620Details
BioGPS NCI60203657_s_atSNB7527.07717.620Details
BioGPS NCI60203657_s_atSR8.72517.620Details
BioGPS NCI60203657_s_atSW6208.62617.620Details
BioGPS NCI60203657_s_atT248.72417.620Details
BioGPS NCI60203657_s_atT3M48.77617.620Details
BioGPS NCI60203657_s_atTK108.62717.620Details
BioGPS NCI60203657_s_atU1189.80817.620Details
BioGPS NCI60203657_s_atU1388.72517.620Details
BioGPS NCI60203657_s_atU20S7.51017.620Details
BioGPS NCI60203657_s_atU2518.51617.620Details
BioGPS NCI60203657_s_atU8729.07817.620Details
BioGPS NCI60203657_s_atUACC25733.36417.620Details
BioGPS NCI60203657_s_atUACC6210.52617.620Details
BioGPS NCI60203657_s_atUO317.48417.620Details
BioGPS NCI60203657_s_atZR75_138.90317.620Details
BioGPS NCI60203657_s_atastrocytes9.30317.620Details
BioGPS NCI60203657_s_athuh-78.96617.620Details