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Gene ID: 5476 | CTSA Antibody Resource


CTSA Antibody Resource
Gene Full Name: 
cathepsin A
Uniprot: 
P10619
Protein Name: 
lysosomal protective protein
Nucleotide: 
NM_001127695
Alias: 
GSL;GLB2;NGBE;PPCA;PPGB;
Ensembl: 
ENSG00000064601
Location: 
20q13.1
HPRD: 
02020
NCBI Gene: 
5476
MIM: 
613111

Summary: 
This gene encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function: 
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
Subcellular location: 
Lysosome.
PTM: 
Disulfide bond;
Disease: 
Galactosialidosis (GSL) [MIM:256540]: A lysosomal storage disease associated with a combined deficiency of beta-galactosidase and neuraminidase, secondary to a defect in cathepsin A. All patients have clinical manifestations typical of a lysosomal disorder, such as coarse facies, cherry red spots, vertebral changes, foam cells in the bone marrow, and vacuolated lymphocytes. Three phenotypic subtypes are recognized. The early infantile form is associated with fetal hydrops, edema, ascites, visceromegaly, skeletal dysplasia, and early death. The late infantile type is characterized by hepatosplenomegaly, growth retardation, cardiac involvement, and a normal or mildly affected mental state. The juvenile/adult form is characterized by myoclonus, ataxia, angiokeratoma, mental retardation, neurologic deterioration, absence of visceromegaly, and long survival. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB00489 CTSA antibody - N-terminal region (OAAB00489) Human; Mouse WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP63511_P050 CTSA Antibody (ARP63511_P050) Polyclonal Guinea pig, Horse, Human, Mouse, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP63512_P050 CTSA Antibody (ARP63512_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAEC01782 PPGB (32k,Cleaved-Arg326) Antibody (OAEC01782) Human; Mouse WB, ELISA 100ug $229 Details
Polyclonal Antibody OAAF05384 CTSA (32k, Cleaved-Arg326) Antibody (OAAF05384) Polyclonal Human, Mouse WB, ELISA 100 ug $229 Details

Show all CTSA antibodies


Product Images
CTSA antibody - N-terminal region (OAAB00489) in HepG2 cells using Western Blot

Sample Type: HepG2

CTSA antibody - N-terminal region (OAAB00489) in human hepatocarcinoma cells using Immunohistochemistry

Sample Type: human hepatocarcinoma

CTSA antibody - N-terminal region (OAAB00489) in mouse bladder cells using Western Blot

Sample Type: mouse bladder

CTSA (32k, Cleaved-Arg326) Antibody (OAAF05384) in Jurkat, 293 cells using Western Blot

Sample Type: Jurkat, 293

PPGB (32k,Cleaved-Arg326) Antibody (OAEC01782) in Jurkat cells using Western Blot

Sample Type: Jurkat


CTSA Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP63512 Bovine CTSA antibody; Bos taurus CTSA antibody Q3MI05 86.0%
ARP63511 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7APT9 100.0%
ARP63512 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7APT9 100.0%
ARP63511 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7AVN6 100.0%
ARP63512 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7AVN6 100.0%
ARP63511 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7DGW3 100.0%
ARP63512 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7DGW3 100.0%
ARP63511 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7DKL0 100.0%
ARP63512 Chimpanzee CTSA antibody; Pan troglodytes CTSA antibody K7DKL0 100.0%
ARP63512 Dog CTSA antibody; Canis familiaris CTSA antibody F1P9I9 85.0%
ARP63512 European domestic ferret CTSA antibody; Mustela putorius furo CTSA antibody M3Z1N8 85.0%
ARP63512 Giant panda CTSA antibody; Ailuropoda melanoleuca CTSA antibody D2HZ11 85.0%
ARP63512 Gray short-tailed opossum CTSA antibody; Monodelphis domestica CTSA antibody F6YAH2 86.0%
ARP63512 Horse CTSA antibody; Equus caballus CTSA antibody F6QJ78 86.0%
ARP63511 Horse CTSA antibody; Equus caballus CTSA antibody F6QJ78 83.0%
ARP63511 Human CTSA antibody; Homo sapiens CTSA antibody P10619 100.0%
ARP63512 Human CTSA antibody; Homo sapiens CTSA antibody P10619 100.0%
ARP63511 Human CTSA antibody; Homo sapiens CTSA antibody Q5JZG9 100.0%
ARP63512 Human CTSA antibody; Homo sapiens CTSA antibody Q5JZG9 100.0%
ARP63511 Human CTSA antibody; Homo sapiens CTSA antibody U3KQ41 100.0%
ARP63512 Human CTSA antibody; Homo sapiens CTSA antibody U3KQ41 100.0%
ARP63511 Human CTSA antibody; Homo sapiens CTSA antibody U3KQF1 100.0%
ARP63511 Human CTSA antibody; Homo sapiens CTSA antibody U3KQU6 100.0%
ARP63512 Human CTSA antibody; Homo sapiens CTSA antibody U3KQU6 100.0%
ARP63511 Mouse CTSA antibody; Mus musculus CTSA antibody P16675 91.0%
ARP63511 Mouse CTSA antibody; Mus musculus CTSA antibody Q544R6 91.0%
ARP63511 Mouse CTSA antibody; Mus musculus CTSA antibody A2A5J8 91.0%
ARP63511 Mouse CTSA antibody; Mus musculus CTSA antibody Q9D2D1 91.0%
ARP63511 Mouse CTSA antibody; Mus musculus CTSA antibody A2A5J9 91.0%
ARP63511 Mouse CTSA antibody; Mus musculus CTSA antibody G3X8T3 91.0%
ARP63512 Mouse CTSA antibody; Mus musculus CTSA antibody G3X8T3 86.0%
ARP63512 Mouse CTSA antibody; Mus musculus CTSA antibody P16675 86.0%
ARP63512 Mouse CTSA antibody; Mus musculus CTSA antibody Q544R6 86.0%
ARP63512 Mouse CTSA antibody; Mus musculus CTSA antibody A2A5J6 86.0%
ARP63512 Mouse CTSA antibody; Mus musculus CTSA antibody A2A5J8 86.0%
ARP63512 Mouse CTSA antibody; Mus musculus CTSA antibody Q9D2D1 86.0%
ARP63512 Mouse CTSA antibody; Mus musculus CTSA antibody A2A5J9 86.0%
ARP63511 Northern white-cheeked gibbon CTSA antibody; Nomascus leucogenys CTSA antibody M3ZAP1 100.0%
ARP63512 Northern white-cheeked gibbon CTSA antibody; Nomascus leucogenys CTSA antibody M3ZAP1 100.0%
ARP63511 Northern white-cheeked gibbon CTSA antibody; Nomascus leucogenys CTSA antibody G1R517 100.0%
ARP63512 Northern white-cheeked gibbon CTSA antibody; Nomascus leucogenys CTSA antibody G1R517 100.0%
ARP63512 Pig CTSA antibody; Sus scrofa CTSA antibody F1SC70 86.0%
ARP63512 Rabbit CTSA antibody; Oryctolagus cuniculus CTSA antibody G1SDZ0 86.0%
ARP63511 Rat CTSA antibody; Rattus norvegicus CTSA antibody Q6AYS3 91.0%
ARP63512 Rat CTSA antibody; Rattus norvegicus CTSA antibody Q6AYS3 86.0%
ARP63511 Rhesus macaque CTSA antibody; Macaca mulatta CTSA antibody F6RBN1 100.0%
ARP63512 Rhesus macaque CTSA antibody; Macaca mulatta CTSA antibody F6RBN1 100.0%
ARP63511 Rhesus macaque CTSA antibody; Macaca mulatta CTSA antibody F7G1E1 100.0%
ARP63512 Rhesus macaque CTSA antibody; Macaca mulatta CTSA antibody F7G1E1 100.0%
ARP63512 Small-eared galago CTSA antibody; Otolemur garnettii CTSA antibody H0WR38 93.0%
ARP63511 Small-eared galago CTSA antibody; Otolemur garnettii CTSA antibody H0WR38 92.0%
ARP63512 Sumatran orangutan CTSA antibody; Pongo abelii CTSA antibody H2P250 100.0%
ARP63511 Sumatran orangutan CTSA antibody; Pongo abelii CTSA antibody H2P250 93.0%
ARP63512 Tasmanian devil CTSA antibody; Sarcophilus harrisii CTSA antibody G3VL36 86.0%
ARP63512 Thirteen-lined ground squirrel CTSA antibody; Spermophilus tridecemlineatus CTSA antibody I3MY47 93.0%
ARP63512 Western clawed frog CTSA antibody; Xenopus tropicalis CTSA antibody Q28C48 100.0%
ARP63512 Western clawed frog CTSA antibody; Xenopus tropicalis CTSA antibody F6S0F9 100.0%
ARP63511 White-tufted-ear marmoset CTSA antibody; Callithrix jacchus CTSA antibody U3EL03 100.0%
ARP63512 White-tufted-ear marmoset CTSA antibody; Callithrix jacchus CTSA antibody U3EL03 100.0%
ARP63511 White-tufted-ear marmoset CTSA antibody; Callithrix jacchus CTSA antibody F7GMX2 100.0%
ARP63512 White-tufted-ear marmoset CTSA antibody; Callithrix jacchus CTSA antibody F7GMX2 100.0%
ARP63511 White-tufted-ear marmoset CTSA antibody; Callithrix jacchus CTSA antibody F7IA20 100.0%
ARP63512 White-tufted-ear marmoset CTSA antibody; Callithrix jacchus CTSA antibody F7IA20 100.0%
ARP63512 Zebrafish CTSA antibody; Danio rerio CTSA antibody Q6PHJ3 86.0%
ARP63512 Zebrafish CTSA antibody; Danio rerio CTSA antibody F1QKN4 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas200661_at721_B_lymphoblasts199.100399.060Details
BioGPS Gene Atlas200661_atAdipocyte576.100399.060Details
BioGPS Gene Atlas200661_atAdrenalCortex753.350399.060Details
BioGPS Gene Atlas200661_atAdrenalgland1580.200399.060Details
BioGPS Gene Atlas200661_atAmygdala135.200399.060Details
BioGPS Gene Atlas200661_atAppendix32.650399.060Details
BioGPS Gene Atlas200661_atAtrioventricularNode21.900399.060Details
BioGPS Gene Atlas200661_atBDCA4+_DentriticCells422.500399.060Details
BioGPS Gene Atlas200661_atBonemarrow305.800399.060Details
BioGPS Gene Atlas200661_atBronchialEpithelialCells50.100399.060Details
BioGPS Gene Atlas200661_atCD105+_Endothelial111.700399.060Details
BioGPS Gene Atlas200661_atCD14+_Monocytes1878.050399.060Details
BioGPS Gene Atlas200661_atCD19+_BCells(neg._sel.)150.850399.060Details
BioGPS Gene Atlas200661_atCD33+_Myeloid2909.700399.060Details
BioGPS Gene Atlas200661_atCD34+372.750399.060Details
BioGPS Gene Atlas200661_atCD4+_Tcells373.400399.060Details
BioGPS Gene Atlas200661_atCD56+_NKCells274.900399.060Details
BioGPS Gene Atlas200661_atCD71+_EarlyErythroid47.050399.060Details
BioGPS Gene Atlas200661_atCD8+_Tcells495.700399.060Details
BioGPS Gene Atlas200661_atCardiacMyocytes483.250399.060Details
BioGPS Gene Atlas200661_atCaudatenucleus100.750399.060Details
BioGPS Gene Atlas200661_atCerebellum115.800399.060Details
BioGPS Gene Atlas200661_atCerebellumPeduncles98.950399.060Details
BioGPS Gene Atlas200661_atCiliaryGanglion23.400399.060Details
BioGPS Gene Atlas200661_atCingulateCortex104.150399.060Details
BioGPS Gene Atlas200661_atColorectaladenocarcinoma379.100399.060Details
BioGPS Gene Atlas200661_atDorsalRootGanglion55.100399.060Details
BioGPS Gene Atlas200661_atFetalThyroid167.400399.060Details
BioGPS Gene Atlas200661_atFetalbrain87.550399.060Details
BioGPS Gene Atlas200661_atFetalliver159.750399.060Details
BioGPS Gene Atlas200661_atFetallung289.800399.060Details
BioGPS Gene Atlas200661_atGlobusPallidus35.500399.060Details
BioGPS Gene Atlas200661_atHeart426.250399.060Details
BioGPS Gene Atlas200661_atHypothalamus238.400399.060Details
BioGPS Gene Atlas200661_atKidney1268.300399.060Details
BioGPS Gene Atlas200661_atLeukemia_chronicMyelogenousK-56243.800399.060Details
BioGPS Gene Atlas200661_atLeukemia_promyelocytic-HL-6039.000399.060Details
BioGPS Gene Atlas200661_atLeukemialymphoblastic(MOLT-4)39.400399.060Details
BioGPS Gene Atlas200661_atLiver472.550399.060Details
BioGPS Gene Atlas200661_atLung838.900399.060Details
BioGPS Gene Atlas200661_atLymphnode387.350399.060Details
BioGPS Gene Atlas200661_atLymphoma_burkitts(Daudi)35.800399.060Details
BioGPS Gene Atlas200661_atLymphoma_burkitts(Raji)67.450399.060Details
BioGPS Gene Atlas200661_atMedullaOblongata69.550399.060Details
BioGPS Gene Atlas200661_atOccipitalLobe111.000399.060Details
BioGPS Gene Atlas200661_atOlfactoryBulb191.550399.060Details
BioGPS Gene Atlas200661_atOvary60.350399.060Details
BioGPS Gene Atlas200661_atPancreas183.900399.060Details
BioGPS Gene Atlas200661_atPancreaticIslet530.300399.060Details
BioGPS Gene Atlas200661_atParietalLobe84.650399.060Details
BioGPS Gene Atlas200661_atPituitary150.550399.060Details
BioGPS Gene Atlas200661_atPlacenta888.750399.060Details
BioGPS Gene Atlas200661_atPons27.550399.060Details
BioGPS Gene Atlas200661_atPrefrontalCortex213.850399.060Details
BioGPS Gene Atlas200661_atProstate242.400399.060Details
BioGPS Gene Atlas200661_atSalivarygland46.100399.060Details
BioGPS Gene Atlas200661_atSkeletalMuscle33.300399.060Details
BioGPS Gene Atlas200661_atSkin24.850399.060Details
BioGPS Gene Atlas200661_atSmoothMuscle938.750399.060Details
BioGPS Gene Atlas200661_atSpinalcord135.300399.060Details
BioGPS Gene Atlas200661_atSubthalamicNucleus49.800399.060Details
BioGPS Gene Atlas200661_atSuperiorCervicalGanglion21.150399.060Details
BioGPS Gene Atlas200661_atTemporalLobe69.400399.060Details
BioGPS Gene Atlas200661_atTestis165.000399.060Details
BioGPS Gene Atlas200661_atTestisGermCell122.050399.060Details
BioGPS Gene Atlas200661_atTestisIntersitial38.600399.060Details
BioGPS Gene Atlas200661_atTestisLeydigCell47.600399.060Details
BioGPS Gene Atlas200661_atTestisSeminiferousTubule68.200399.060Details
BioGPS Gene Atlas200661_atThalamus158.700399.060Details
BioGPS Gene Atlas200661_atThymus191.600399.060Details
BioGPS Gene Atlas200661_atThyroid360.000399.060Details
BioGPS Gene Atlas200661_atTongue158.350399.060Details
BioGPS Gene Atlas200661_atTonsil150.000399.060Details
BioGPS Gene Atlas200661_atTrachea100.900399.060Details
BioGPS Gene Atlas200661_atTrigeminalGanglion28.750399.060Details
BioGPS Gene Atlas200661_atUterus180.300399.060Details
BioGPS Gene Atlas200661_atUterusCorpus193.050399.060Details
BioGPS Gene Atlas200661_atWholeBlood947.400399.060Details
BioGPS Gene Atlas200661_atWholebrain273.850399.060Details
BioGPS Gene Atlas200661_atcolon497.050399.060Details
BioGPS Gene Atlas200661_atpineal_day1446.940399.060Details
BioGPS Gene Atlas200661_atpineal_night2294.620399.060Details
BioGPS Gene Atlas200661_atretina594.650399.060Details
BioGPS Gene Atlas200661_atsmall_intestine170.700399.060Details
BioGPS NCI60200661_at786823.7251705.530Details
BioGPS NCI60200661_atA1724048.2291705.530Details
BioGPS NCI60200661_atA2041267.0401705.530Details
BioGPS NCI60200661_atA3612435.3721705.530Details
BioGPS NCI60200661_atA4982953.8751705.530Details
BioGPS NCI60200661_atA549523.5461705.530Details
BioGPS NCI60200661_atACC3733.0861705.530Details
BioGPS NCI60200661_atACHN1685.8531705.530Details
BioGPS NCI60200661_atALVA31589.3801705.530Details
BioGPS NCI60200661_atCAKI11326.4821705.530Details
BioGPS NCI60200661_atCCRT CEM124.7661705.530Details
BioGPS NCI60200661_atCOLO205985.4931705.530Details
BioGPS NCI60200661_atDLD1631.4701705.530Details
BioGPS NCI60200661_atDU1451499.7141705.530Details
BioGPS NCI60200661_atEKVX2007.9141705.530Details
BioGPS NCI60200661_atGM1331346.8161705.530Details
BioGPS NCI60200661_atGM16002547.0431705.530Details
BioGPS NCI60200661_atGM23132071.3171705.530Details
BioGPS NCI60200661_atGM2345803.0691705.530Details
BioGPS NCI60200661_atGM24931487.5101705.530Details
BioGPS NCI60200661_atGM974145.1321705.530Details
BioGPS NCI60200661_atHCC29981174.1891705.530Details
BioGPS NCI60200661_atHCT116812.7161705.530Details
BioGPS NCI60200661_atHCT15700.8681705.530Details
BioGPS NCI60200661_atHEK 293 T-rex32.2481705.530Details
BioGPS NCI60200661_atHEK 293T55.1521705.530Details
BioGPS NCI60200661_atHEK293219.6511705.530Details
BioGPS NCI60200661_atHELA918.8871705.530Details
BioGPS NCI60200661_atHEPG22978.4151705.530Details
BioGPS NCI60200661_atHL6026.6011705.530Details
BioGPS NCI60200661_atHOP622772.3141705.530Details
BioGPS NCI60200661_atHOP921042.7721705.530Details
BioGPS NCI60200661_atHS578T1547.7411705.530Details
BioGPS NCI60200661_atHSG1529.2811705.530Details
BioGPS NCI60200661_atHT10801100.5231705.530Details
BioGPS NCI60200661_atHT291104.5711705.530Details
BioGPS NCI60200661_atIGROV11824.6421705.530Details
BioGPS NCI60200661_atIOSE801181.4061705.530Details
BioGPS NCI60200661_atJURKAT172.0971705.530Details
BioGPS NCI60200661_atK56276.9361705.530Details
BioGPS NCI60200661_atKM121154.9931705.530Details
BioGPS NCI60200661_atLN181844.9631705.530Details
BioGPS NCI60200661_atLNCAP172.3551705.530Details
BioGPS NCI60200661_atLOX IMVI663.3591705.530Details
BioGPS NCI60200661_atM142511.4531705.530Details
BioGPS NCI60200661_atMALME 3M3481.8631705.530Details
BioGPS NCI60200661_atMCF7676.2441705.530Details
BioGPS NCI60200661_atMD MB2311105.1711705.530Details
BioGPS NCI60200661_atMDA MB4355631.3061705.530Details
BioGPS NCI60200661_atMOLT4106.8191705.530Details
BioGPS NCI60200661_atNCI 460568.3151705.530Details
BioGPS NCI60200661_atNCI H2261325.6321705.530Details
BioGPS NCI60200661_atNCI H232479.3511705.530Details
BioGPS NCI60200661_atNCI H322M1316.7671705.530Details
BioGPS NCI60200661_atNCVADR RES1145.7231705.530Details
BioGPS NCI60200661_atOVCAR3793.1491705.530Details
BioGPS NCI60200661_atOVCAR4913.8821705.530Details
BioGPS NCI60200661_atOVCAR5880.2441705.530Details
BioGPS NCI60200661_atOVCAR8758.2781705.530Details
BioGPS NCI60200661_atPANC1800.8711705.530Details
BioGPS NCI60200661_atRL767.5971705.530Details
BioGPS NCI60200661_atRPMI 8226777.6551705.530Details
BioGPS NCI60200661_atRS1184691.7081705.530Details
BioGPS NCI60200661_atRXF3932484.0811705.530Details
BioGPS NCI60200661_atSAOS21081.2081705.530Details
BioGPS NCI60200661_atSF2681363.3511705.530Details
BioGPS NCI60200661_atSF295875.9831705.530Details
BioGPS NCI60200661_atSF5391041.2701705.530Details
BioGPS NCI60200661_atSHSYSY+RA95.3361705.530Details
BioGPS NCI60200661_atSHSYSY-RA360.9621705.530Details
BioGPS NCI60200661_atSKMEL24016.7331705.530Details
BioGPS NCI60200661_atSKMEL282578.9391705.530Details
BioGPS NCI60200661_atSKMEL57675.0891705.530Details
BioGPS NCI60200661_atSKOV3121.2971705.530Details
BioGPS NCI60200661_atSN12C3319.1121705.530Details
BioGPS NCI60200661_atSNB19727.1451705.530Details
BioGPS NCI60200661_atSNB752546.5391705.530Details
BioGPS NCI60200661_atSR347.7521705.530Details
BioGPS NCI60200661_atSW620860.6451705.530Details
BioGPS NCI60200661_atT241310.8261705.530Details
BioGPS NCI60200661_atT3M4644.8831705.530Details
BioGPS NCI60200661_atTK10809.4621705.530Details
BioGPS NCI60200661_atU1188397.4831705.530Details
BioGPS NCI60200661_atU1384950.9541705.530Details
BioGPS NCI60200661_atU20S452.3991705.530Details
BioGPS NCI60200661_atU251660.7541705.530Details
BioGPS NCI60200661_atU878240.1621705.530Details
BioGPS NCI60200661_atUACC2573835.9881705.530Details
BioGPS NCI60200661_atUACC624091.8261705.530Details
BioGPS NCI60200661_atUO311229.6941705.530Details
BioGPS NCI60200661_atZR75_11166.9631705.530Details
BioGPS NCI60200661_atastrocytes499.6351705.530Details
BioGPS NCI60200661_athuh-71225.1711705.530Details