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Gene ID: 9150 | CTDP1 Antibody Resource


CTDP1 Antibody Resource
Gene Full Name: 
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Uniprot: 
Q9Y5B0
Protein Name: 
RNA polymerase II subunit A C-terminal domain phosphatase
Nucleotide: 
NM_004715
Alias: 
FCP1;CCFDN;
Ensembl: 
ENSG00000060069
Location: 
18q23
HPRD: 
05377
NCBI Gene: 
9150
MIM: 
604927

Summary: 
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Function: 
Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation.
Subcellular location: 
Nucleus. Cytoplasm › cytoskeleton › microtubule organizing center › centrosome. Cytoplasm › cytoskeleton › spindle. Cytoplasm › cytoskeleton › spindle pole. Midbody. Note: Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively.
PTM: 
Acetylation;
Disease: 
Congenital cataracts, facial dysmorphism, and neuropathy (CCFDN) [MIM:604168]: An autosomal recessive developmental disorder characterized by a complex clinical phenotype with seemingly unrelated features involving multiple organs and systems. Developmental abnormalities include congenital cataracts and microcorneae, hypomyelination of the peripheral nervous system, impaired physical growth, delayed early motor and intellectual development, facial dysmorphism and hypogonadism. Central nervous system involvement, with cerebral and spinal cord atrophy, may be the result of disrupted development with superimposed degenerative changes. Affected individuals are prone to severe rhabdomyolysis after viral infections and to serious complications related to general anesthesia (such as pulmonary edema and epileptic seizures). Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB00235 Goat Anti-FCP1 / CTDP1 Antibody (OAEB00235) ELISA 0.1mg $190 Details
Polyclonal Antibody OAAB03666 CTDP1 antibody - N-terminal region (OAAB03666) Human WB, IHC, FC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB03667 CTDP1 antibody - C-terminal region (OAAB03667) Human WB, FC, ELISA 400ul $289 Details
Polyclonal Antibody ARP65744_P050 CTDP1 Antibody - C-terminal region (ARP65744_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP65743_P050 CTDP1 Antibody (ARP65743_P050) Polyclonal Human Not tested 50 ug $125 Details

Show all CTDP1 antibodies


Product Images
CTDP1 Antibody - C-terminal region (ARP65744_P050) in Human Fetal Kidney cells using Western Blot

Sample Type: Human Fetal Kidney

CTDP1 antibody - N-terminal region (OAAB03666) in 293 cells using Western Blot

Sample Type: 293

CTDP1 antibody - N-terminal region (OAAB03666) in human brain cells using Immunohistochemistry

Sample Type: human brain

CTDP1 antibody - N-terminal region (OAAB03666) in WiDr cells using Flow Cytometry

Sample Type: WiDr


CTDP1 Protocols

Publications
Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP65744 African clawed frog CTDP1 antibody; Xenopus laevis CTDP1 antibody Q641F9 85.0%
ARP65744 Cat CTDP1 antibody; Felis catus CTDP1 antibody M3VV05 100.0%
ARP65744 Chicken CTDP1 antibody; Gallus gallus CTDP1 antibody F1NZN8 93.0%
ARP65744 Chimpanzee CTDP1 antibody; Pan troglodytes CTDP1 antibody H2QER0 100.0%
ARP65744 Chimpanzee CTDP1 antibody; Pan troglodytes CTDP1 antibody K6ZJ11 100.0%
ARP65744 Chimpanzee CTDP1 antibody; Pan troglodytes CTDP1 antibody K7CNU2 100.0%
ARP65744 Chinese softshell turtle CTDP1 antibody; Pelodiscus sinensis CTDP1 antibody K7FCQ3 93.0%
ARP65744 Collared flycatcher CTDP1 antibody; Ficedula albicollis CTDP1 antibody U3KFV6 85.0%
ARP65744 Dog CTDP1 antibody; Canis familiaris CTDP1 antibody E2R1Y2 100.0%
ARP65744 Domestic duck CTDP1 antibody; Anas platyrhynchos CTDP1 antibody U3J536 93.0%
ARP65744 Duckbill platypus CTDP1 antibody; Ornithorhynchus anatinus CTDP1 antibody F7F659 86.0%
ARP65744 Duckbill platypus CTDP1 antibody; Ornithorhynchus anatinus CTDP1 antibody F7F664 86.0%
ARP65744 European domestic ferret CTDP1 antibody; Mustela putorius furo CTDP1 antibody M3YYY9 100.0%
ARP65744 Gray short-tailed opossum CTDP1 antibody; Monodelphis domestica CTDP1 antibody F7B931 92.0%
ARP65744 Guinea pig CTDP1 antibody; Cavia porcellus CTDP1 antibody H0UYY7 92.0%
ARP65744 Horse CTDP1 antibody; Equus caballus CTDP1 antibody F6WRF7 100.0%
ARP65743 Human CTDP1 antibody; Homo sapiens CTDP1 antibody Q9Y5B0-2 100.0%
ARP65744 Human CTDP1 antibody; Homo sapiens CTDP1 antibody Q9Y5B0-2 100.0%
ARP65744 Human CTDP1 antibody; Homo sapiens CTDP1 antibody Q9Y5B0-3 100.0%
ARP65743 Human CTDP1 antibody; Homo sapiens CTDP1 antibody Q9Y5B0-4 100.0%
ARP65744 Human CTDP1 antibody; Homo sapiens CTDP1 antibody Q9Y5B0-4 100.0%
ARP65744 Human CTDP1 antibody; Homo sapiens CTDP1 antibody Q9Y5B0 100.0%
ARP65744 Human CTDP1 antibody; Homo sapiens CTDP1 antibody K7EJD2 100.0%
ARP65744 Mouse CTDP1 antibody; Mus musculus CTDP1 antibody Q7TSG2 100.0%
ARP65744 Mouse CTDP1 antibody; Mus musculus CTDP1 antibody Q3U0S4 100.0%
ARP65744 Pig CTDP1 antibody; Sus scrofa CTDP1 antibody F1RWS7 100.0%
ARP65744 Rabbit CTDP1 antibody; Oryctolagus cuniculus CTDP1 antibody G1SKL9 100.0%
ARP65744 Rat CTDP1 antibody; Rattus norvegicus CTDP1 antibody D3ZMS2 100.0%
ARP65744 Rhesus macaque CTDP1 antibody; Macaca mulatta CTDP1 antibody F7E4V3 100.0%
ARP65744 Rhesus macaque CTDP1 antibody; Macaca mulatta CTDP1 antibody F7HRQ5 100.0%
ARP65743 Rhesus macaque CTDP1 antibody; Macaca mulatta CTDP1 antibody F7HRQ5 86.0%
ARP65744 Small-eared galago CTDP1 antibody; Otolemur garnettii CTDP1 antibody H0XQT5 100.0%
ARP65744 Sumatran orangutan CTDP1 antibody; Pongo abelii CTDP1 antibody H2NWM9 100.0%
ARP65744 Tasmanian devil CTDP1 antibody; Sarcophilus harrisii CTDP1 antibody G3WH29 93.0%
ARP65744 Tasmanian devil CTDP1 antibody; Sarcophilus harrisii CTDP1 antibody G3WH30 93.0%
ARP65744 Thirteen-lined ground squirrel CTDP1 antibody; Spermophilus tridecemlineatus CTDP1 antibody I3MHY0 100.0%
ARP65744 Western clawed frog CTDP1 antibody; Xenopus tropicalis CTDP1 antibody F7AG65 85.0%
ARP65744 Western clawed frog CTDP1 antibody; Xenopus tropicalis CTDP1 antibody F7B1B3 85.0%
ARP65744 Western clawed frog CTDP1 antibody; Xenopus tropicalis CTDP1 antibody Q28F82 85.0%
ARP65744 White-tufted-ear marmoset CTDP1 antibody; Callithrix jacchus CTDP1 antibody U3B9J0 100.0%
ARP65744 White-tufted-ear marmoset CTDP1 antibody; Callithrix jacchus CTDP1 antibody U3CFF3 100.0%
ARP65744 White-tufted-ear marmoset CTDP1 antibody; Callithrix jacchus CTDP1 antibody U3DU16 100.0%
ARP65744 Zebra finch CTDP1 antibody; Taeniopygia guttata CTDP1 antibody H0Z8E0 85.0%
ARP65744 Zebrafish CTDP1 antibody; Danio rerio CTDP1 antibody E7FFL3 85.0%
ARP65744 Zebrafish CTDP1 antibody; Danio rerio CTDP1 antibody F8W4I4 85.0%
ARP65744 Zebrafish CTDP1 antibody; Danio rerio CTDP1 antibody Q6DRN5 85.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205035_at721_B_lymphoblasts9.0006.350Details
BioGPS Gene Atlas205035_atAdipocyte5.7506.350Details
BioGPS Gene Atlas205035_atAdrenalCortex5.8506.350Details
BioGPS Gene Atlas205035_atAdrenalgland4.4006.350Details
BioGPS Gene Atlas205035_atAmygdala5.5006.350Details
BioGPS Gene Atlas205035_atAppendix5.1506.350Details
BioGPS Gene Atlas205035_atAtrioventricularNode4.0506.350Details
BioGPS Gene Atlas205035_atBDCA4+_DentriticCells28.9006.350Details
BioGPS Gene Atlas205035_atBonemarrow5.2006.350Details
BioGPS Gene Atlas205035_atBronchialEpithelialCells5.1006.350Details
BioGPS Gene Atlas205035_atCD105+_Endothelial5.3006.350Details
BioGPS Gene Atlas205035_atCD14+_Monocytes30.1006.350Details
BioGPS Gene Atlas205035_atCD19+_BCells(neg._sel.)10.2506.350Details
BioGPS Gene Atlas205035_atCD33+_Myeloid8.4006.350Details
BioGPS Gene Atlas205035_atCD34+6.5006.350Details
BioGPS Gene Atlas205035_atCD4+_Tcells7.3506.350Details
BioGPS Gene Atlas205035_atCD56+_NKCells10.7506.350Details
BioGPS Gene Atlas205035_atCD71+_EarlyErythroid6.5006.350Details
BioGPS Gene Atlas205035_atCD8+_Tcells5.1006.350Details
BioGPS Gene Atlas205035_atCardiacMyocytes5.6506.350Details
BioGPS Gene Atlas205035_atCaudatenucleus4.7506.350Details
BioGPS Gene Atlas205035_atCerebellum4.2006.350Details
BioGPS Gene Atlas205035_atCerebellumPeduncles5.9006.350Details
BioGPS Gene Atlas205035_atCiliaryGanglion3.8506.350Details
BioGPS Gene Atlas205035_atCingulateCortex5.3506.350Details
BioGPS Gene Atlas205035_atColorectaladenocarcinoma5.0506.350Details
BioGPS Gene Atlas205035_atDorsalRootGanglion4.0006.350Details
BioGPS Gene Atlas205035_atFetalThyroid5.5506.350Details
BioGPS Gene Atlas205035_atFetalbrain5.6506.350Details
BioGPS Gene Atlas205035_atFetalliver4.4506.350Details
BioGPS Gene Atlas205035_atFetallung4.1006.350Details
BioGPS Gene Atlas205035_atGlobusPallidus3.8006.350Details
BioGPS Gene Atlas205035_atHeart6.5006.350Details
BioGPS Gene Atlas205035_atHypothalamus5.7506.350Details
BioGPS Gene Atlas205035_atKidney4.6506.350Details
BioGPS Gene Atlas205035_atLeukemia_chronicMyelogenousK-5624.7006.350Details
BioGPS Gene Atlas205035_atLeukemia_promyelocytic-HL-605.4006.350Details
BioGPS Gene Atlas205035_atLeukemialymphoblastic(MOLT-4)5.1506.350Details
BioGPS Gene Atlas205035_atLiver6.8506.350Details
BioGPS Gene Atlas205035_atLung14.9006.350Details
BioGPS Gene Atlas205035_atLymphnode4.8006.350Details
BioGPS Gene Atlas205035_atLymphoma_burkitts(Daudi)6.7006.350Details
BioGPS Gene Atlas205035_atLymphoma_burkitts(Raji)7.1506.350Details
BioGPS Gene Atlas205035_atMedullaOblongata4.7006.350Details
BioGPS Gene Atlas205035_atOccipitalLobe4.8006.350Details
BioGPS Gene Atlas205035_atOlfactoryBulb4.0506.350Details
BioGPS Gene Atlas205035_atOvary3.4506.350Details
BioGPS Gene Atlas205035_atPancreas4.1506.350Details
BioGPS Gene Atlas205035_atPancreaticIslet5.4506.350Details
BioGPS Gene Atlas205035_atParietalLobe5.5006.350Details
BioGPS Gene Atlas205035_atPituitary6.7506.350Details
BioGPS Gene Atlas205035_atPlacenta6.7006.350Details
BioGPS Gene Atlas205035_atPons5.0006.350Details
BioGPS Gene Atlas205035_atPrefrontalCortex6.3506.350Details
BioGPS Gene Atlas205035_atProstate6.9506.350Details
BioGPS Gene Atlas205035_atSalivarygland4.1506.350Details
BioGPS Gene Atlas205035_atSkeletalMuscle6.0506.350Details
BioGPS Gene Atlas205035_atSkin3.9506.350Details
BioGPS Gene Atlas205035_atSmoothMuscle6.1506.350Details
BioGPS Gene Atlas205035_atSpinalcord5.7006.350Details
BioGPS Gene Atlas205035_atSubthalamicNucleus4.8506.350Details
BioGPS Gene Atlas205035_atSuperiorCervicalGanglion6.6006.350Details
BioGPS Gene Atlas205035_atTemporalLobe4.8506.350Details
BioGPS Gene Atlas205035_atTestis16.6506.350Details
BioGPS Gene Atlas205035_atTestisGermCell5.1506.350Details
BioGPS Gene Atlas205035_atTestisIntersitial4.4506.350Details
BioGPS Gene Atlas205035_atTestisLeydigCell6.0506.350Details
BioGPS Gene Atlas205035_atTestisSeminiferousTubule4.7006.350Details
BioGPS Gene Atlas205035_atThalamus5.3006.350Details
BioGPS Gene Atlas205035_atThymus4.1506.350Details
BioGPS Gene Atlas205035_atThyroid6.6506.350Details
BioGPS Gene Atlas205035_atTongue5.0506.350Details
BioGPS Gene Atlas205035_atTonsil5.1506.350Details
BioGPS Gene Atlas205035_atTrachea4.3506.350Details
BioGPS Gene Atlas205035_atTrigeminalGanglion5.1506.350Details
BioGPS Gene Atlas205035_atUterus4.1006.350Details
BioGPS Gene Atlas205035_atUterusCorpus4.6006.350Details
BioGPS Gene Atlas205035_atWholeBlood9.6006.350Details
BioGPS Gene Atlas205035_atWholebrain4.4006.350Details
BioGPS Gene Atlas205035_atcolon5.1506.350Details
BioGPS Gene Atlas205035_atpineal_day6.0606.350Details
BioGPS Gene Atlas205035_atpineal_night6.0606.350Details
BioGPS Gene Atlas205035_atretina6.2006.350Details
BioGPS Gene Atlas205035_atsmall_intestine4.9006.350Details
BioGPS NCI60205035_at7865.9947.200Details
BioGPS NCI60205035_atA1725.7107.200Details
BioGPS NCI60205035_atA2045.8617.200Details
BioGPS NCI60205035_atA3618.4017.200Details
BioGPS NCI60205035_atA4985.9097.200Details
BioGPS NCI60205035_atA5496.0187.200Details
BioGPS NCI60205035_atACC36.0277.200Details
BioGPS NCI60205035_atACHN7.7367.200Details
BioGPS NCI60205035_atALVA316.0247.200Details
BioGPS NCI60205035_atCAKI16.0167.200Details
BioGPS NCI60205035_atCCRT CEM11.1837.200Details
BioGPS NCI60205035_atCOLO2055.8597.200Details
BioGPS NCI60205035_atDLD111.0787.200Details
BioGPS NCI60205035_atDU1455.7977.200Details
BioGPS NCI60205035_atEKVX11.2227.200Details
BioGPS NCI60205035_atGM1336.0707.200Details
BioGPS NCI60205035_atGM16006.0827.200Details
BioGPS NCI60205035_atGM23135.9947.200Details
BioGPS NCI60205035_atGM23455.9857.200Details
BioGPS NCI60205035_atGM24936.1207.200Details
BioGPS NCI60205035_atGM976.3597.200Details
BioGPS NCI60205035_atHCC299833.9087.200Details
BioGPS NCI60205035_atHCT11610.0197.200Details
BioGPS NCI60205035_atHCT155.7977.200Details
BioGPS NCI60205035_atHEK 293 T-rex5.9547.200Details
BioGPS NCI60205035_atHEK 293T5.8197.200Details
BioGPS NCI60205035_atHEK2935.9367.200Details
BioGPS NCI60205035_atHELA5.7337.200Details
BioGPS NCI60205035_atHEPG26.2587.200Details
BioGPS NCI60205035_atHL607.2507.200Details
BioGPS NCI60205035_atHOP629.0787.200Details
BioGPS NCI60205035_atHOP925.8117.200Details
BioGPS NCI60205035_atHS578T7.3507.200Details
BioGPS NCI60205035_atHSG7.3717.200Details
BioGPS NCI60205035_atHT10805.8707.200Details
BioGPS NCI60205035_atHT296.0957.200Details
BioGPS NCI60205035_atIGROV15.8707.200Details
BioGPS NCI60205035_atIOSE8011.5187.200Details
BioGPS NCI60205035_atJURKAT11.0247.200Details
BioGPS NCI60205035_atK5626.0467.200Details
BioGPS NCI60205035_atKM126.0097.200Details
BioGPS NCI60205035_atLN185.5907.200Details
BioGPS NCI60205035_atLNCAP5.8987.200Details
BioGPS NCI60205035_atLOX IMVI6.5907.200Details
BioGPS NCI60205035_atM145.9067.200Details
BioGPS NCI60205035_atMALME 3M6.0707.200Details
BioGPS NCI60205035_atMCF75.8057.200Details
BioGPS NCI60205035_atMD MB2315.9017.200Details
BioGPS NCI60205035_atMDA MB4356.5687.200Details
BioGPS NCI60205035_atMOLT45.9657.200Details
BioGPS NCI60205035_atNCI 4605.9937.200Details
BioGPS NCI60205035_atNCI H2267.6047.200Details
BioGPS NCI60205035_atNCI H236.1607.200Details
BioGPS NCI60205035_atNCI H322M5.9097.200Details
BioGPS NCI60205035_atNCVADR RES5.5517.200Details
BioGPS NCI60205035_atOVCAR39.2827.200Details
BioGPS NCI60205035_atOVCAR45.8687.200Details
BioGPS NCI60205035_atOVCAR55.8377.200Details
BioGPS NCI60205035_atOVCAR85.8007.200Details
BioGPS NCI60205035_atPANC19.9767.200Details
BioGPS NCI60205035_atRL714.3437.200Details
BioGPS NCI60205035_atRPMI 82266.3957.200Details
BioGPS NCI60205035_atRS118466.4087.200Details
BioGPS NCI60205035_atRXF3938.6747.200Details
BioGPS NCI60205035_atSAOS25.9747.200Details
BioGPS NCI60205035_atSF2685.9267.200Details
BioGPS NCI60205035_atSF2956.2277.200Details
BioGPS NCI60205035_atSF53910.2947.200Details
BioGPS NCI60205035_atSHSYSY+RA5.8787.200Details
BioGPS NCI60205035_atSHSYSY-RA5.8587.200Details
BioGPS NCI60205035_atSKMEL28.4927.200Details
BioGPS NCI60205035_atSKMEL285.9797.200Details
BioGPS NCI60205035_atSKMEL57.4127.200Details
BioGPS NCI60205035_atSKOV35.9517.200Details
BioGPS NCI60205035_atSN12C7.1267.200Details
BioGPS NCI60205035_atSNB195.5737.200Details
BioGPS NCI60205035_atSNB755.8847.200Details
BioGPS NCI60205035_atSR34.5807.200Details
BioGPS NCI60205035_atSW6205.9137.200Details
BioGPS NCI60205035_atT245.9567.200Details
BioGPS NCI60205035_atT3M45.9827.200Details
BioGPS NCI60205035_atTK106.7417.200Details
BioGPS NCI60205035_atU1185.6947.200Details
BioGPS NCI60205035_atU1385.7057.200Details
BioGPS NCI60205035_atU20S5.7857.200Details
BioGPS NCI60205035_atU2515.8997.200Details
BioGPS NCI60205035_atU875.7557.200Details
BioGPS NCI60205035_atUACC2575.8147.200Details
BioGPS NCI60205035_atUACC625.9787.200Details
BioGPS NCI60205035_atUO316.4037.200Details
BioGPS NCI60205035_atZR75_15.9457.200Details
BioGPS NCI60205035_atastrocytes5.8837.200Details
BioGPS NCI60205035_athuh-75.9637.200Details