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Gene ID: 140690 | CTCFL Antibody Resource


CTCFL Antibody Resource
Gene Full Name: 
CCCTC-binding factor (zinc finger protein)-like
Uniprot: 
Q8NI51
Protein Name: 
transcriptional repressor CTCFL
Nucleotide: 
NM_001269043
Alias: 
CT27;BORIS;CTCF-T;HMGB1L1;dJ579F20.2;
Ensembl: 
ENSG00000124092
Location: 
20q13.31
HPRD: 
09512
NCBI Gene: 
140690
MIM: 
607022

Summary: 
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Function: 
Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites . Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
Subcellular location: 
Cytoplasm. Nucleus.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP36128_P050 CTCFL antibody - N-terminal region (ARP36128_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody ARP36127_P050 CTCFL antibody - N-terminal region (ARP36127_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody OARA02106 CTCFL Antibody (OARA02106) Human; chimpanzee ELISA, WB 100ug $475 Details

Show all CTCFL antibodies


Product Images
CTCFL antibody - N-terminal region (ARP36127_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat

CTCFL antibody - N-terminal region (ARP36128_P050) in Human 721_B cells using Western Blot

Sample Type: Human 721_B


CTCFL Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP36128 Chimpanzee CTCFL antibody; Pan troglodytes CTCFL antibody H2QKN0 100.0%
ARP36127 Chimpanzee CTCFL antibody; Pan troglodytes CTCFL antibody H2QKN0 93.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody F5H2V8 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody F5H2V8 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-2 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-2 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-3 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-3 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-4 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-4 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-5 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-7 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-7 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-8 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-8 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-9 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51-9 100.0%
ARP36127 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51 100.0%
ARP36128 Human CTCFL antibody; Homo sapiens CTCFL antibody Q8NI51 100.0%
ARP36127 Northern white-cheeked gibbon CTCFL antibody; Nomascus leucogenys CTCFL antibody G1R5Y4 100.0%
ARP36128 Northern white-cheeked gibbon CTCFL antibody; Nomascus leucogenys CTCFL antibody G1R5Y4 100.0%
ARP36127 Rhesus macaque CTCFL antibody; Macaca mulatta CTCFL antibody F7CYR4 93.0%
ARP36127 Sumatran orangutan CTCFL antibody; Pongo abelii CTCFL antibody H2P2D8 100.0%
ARP36128 Sumatran orangutan CTCFL antibody; Pongo abelii CTCFL antibody H2P2D8 93.0%
ARP38354 Sumatran orangutan CTCFL antibody; Pongo abelii CTCFL antibody H2P2D8 80.0%
ARP36127 Thirteen-lined ground squirrel CTCFL antibody; Spermophilus tridecemlineatus CTCFL antibody I3MNK6 79.0%
ARP36128 White-tufted-ear marmoset CTCFL antibody; Callithrix jacchus CTCFL antibody F7I6B0 92.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas216508_x_at721_B_lymphoblasts728.200214.040Details
BioGPS Gene Atlas216508_x_atAdipocyte178.700214.040Details
BioGPS Gene Atlas216508_x_atAdrenalCortex178.750214.040Details
BioGPS Gene Atlas216508_x_atAdrenalgland113.100214.040Details
BioGPS Gene Atlas216508_x_atAmygdala176.500214.040Details
BioGPS Gene Atlas216508_x_atAppendix198.300214.040Details
BioGPS Gene Atlas216508_x_atAtrioventricularNode155.100214.040Details
BioGPS Gene Atlas216508_x_atBDCA4+_DentriticCells182.000214.040Details
BioGPS Gene Atlas216508_x_atBonemarrow273.000214.040Details
BioGPS Gene Atlas216508_x_atBronchialEpithelialCells224.150214.040Details
BioGPS Gene Atlas216508_x_atCD105+_Endothelial432.150214.040Details
BioGPS Gene Atlas216508_x_atCD14+_Monocytes161.450214.040Details
BioGPS Gene Atlas216508_x_atCD19+_BCells(neg._sel.)200.250214.040Details
BioGPS Gene Atlas216508_x_atCD33+_Myeloid214.850214.040Details
BioGPS Gene Atlas216508_x_atCD34+700.700214.040Details
BioGPS Gene Atlas216508_x_atCD4+_Tcells241.900214.040Details
BioGPS Gene Atlas216508_x_atCD56+_NKCells198.150214.040Details
BioGPS Gene Atlas216508_x_atCD71+_EarlyErythroid586.200214.040Details
BioGPS Gene Atlas216508_x_atCD8+_Tcells195.100214.040Details
BioGPS Gene Atlas216508_x_atCardiacMyocytes453.850214.040Details
BioGPS Gene Atlas216508_x_atCaudatenucleus143.700214.040Details
BioGPS Gene Atlas216508_x_atCerebellum145.400214.040Details
BioGPS Gene Atlas216508_x_atCerebellumPeduncles196.950214.040Details
BioGPS Gene Atlas216508_x_atCiliaryGanglion161.300214.040Details
BioGPS Gene Atlas216508_x_atCingulateCortex183.550214.040Details
BioGPS Gene Atlas216508_x_atColorectaladenocarcinoma271.100214.040Details
BioGPS Gene Atlas216508_x_atDorsalRootGanglion191.150214.040Details
BioGPS Gene Atlas216508_x_atFetalThyroid96.850214.040Details
BioGPS Gene Atlas216508_x_atFetalbrain249.550214.040Details
BioGPS Gene Atlas216508_x_atFetalliver196.450214.040Details
BioGPS Gene Atlas216508_x_atFetallung145.100214.040Details
BioGPS Gene Atlas216508_x_atGlobusPallidus145.600214.040Details
BioGPS Gene Atlas216508_x_atHeart153.500214.040Details
BioGPS Gene Atlas216508_x_atHypothalamus218.100214.040Details
BioGPS Gene Atlas216508_x_atKidney138.900214.040Details
BioGPS Gene Atlas216508_x_atLeukemia_chronicMyelogenousK-562154.050214.040Details
BioGPS Gene Atlas216508_x_atLeukemia_promyelocytic-HL-60213.600214.040Details
BioGPS Gene Atlas216508_x_atLeukemialymphoblastic(MOLT-4)375.450214.040Details
BioGPS Gene Atlas216508_x_atLiver128.300214.040Details
BioGPS Gene Atlas216508_x_atLung135.950214.040Details
BioGPS Gene Atlas216508_x_atLymphnode162.750214.040Details
BioGPS Gene Atlas216508_x_atLymphoma_burkitts(Daudi)373.850214.040Details
BioGPS Gene Atlas216508_x_atLymphoma_burkitts(Raji)254.050214.040Details
BioGPS Gene Atlas216508_x_atMedullaOblongata167.750214.040Details
BioGPS Gene Atlas216508_x_atOccipitalLobe166.500214.040Details
BioGPS Gene Atlas216508_x_atOlfactoryBulb208.100214.040Details
BioGPS Gene Atlas216508_x_atOvary120.450214.040Details
BioGPS Gene Atlas216508_x_atPancreas142.650214.040Details
BioGPS Gene Atlas216508_x_atPancreaticIslet142.550214.040Details
BioGPS Gene Atlas216508_x_atParietalLobe223.100214.040Details
BioGPS Gene Atlas216508_x_atPituitary198.900214.040Details
BioGPS Gene Atlas216508_x_atPlacenta172.150214.040Details
BioGPS Gene Atlas216508_x_atPons132.900214.040Details
BioGPS Gene Atlas216508_x_atPrefrontalCortex211.300214.040Details
BioGPS Gene Atlas216508_x_atProstate168.250214.040Details
BioGPS Gene Atlas216508_x_atSalivarygland140.600214.040Details
BioGPS Gene Atlas216508_x_atSkeletalMuscle112.750214.040Details
BioGPS Gene Atlas216508_x_atSkin139.000214.040Details
BioGPS Gene Atlas216508_x_atSmoothMuscle201.900214.040Details
BioGPS Gene Atlas216508_x_atSpinalcord173.750214.040Details
BioGPS Gene Atlas216508_x_atSubthalamicNucleus168.650214.040Details
BioGPS Gene Atlas216508_x_atSuperiorCervicalGanglion260.200214.040Details
BioGPS Gene Atlas216508_x_atTemporalLobe156.150214.040Details
BioGPS Gene Atlas216508_x_atTestis138.550214.040Details
BioGPS Gene Atlas216508_x_atTestisGermCell146.700214.040Details
BioGPS Gene Atlas216508_x_atTestisIntersitial168.400214.040Details
BioGPS Gene Atlas216508_x_atTestisLeydigCell155.650214.040Details
BioGPS Gene Atlas216508_x_atTestisSeminiferousTubule156.750214.040Details
BioGPS Gene Atlas216508_x_atThalamus163.000214.040Details
BioGPS Gene Atlas216508_x_atThymus345.350214.040Details
BioGPS Gene Atlas216508_x_atThyroid207.750214.040Details
BioGPS Gene Atlas216508_x_atTongue160.050214.040Details
BioGPS Gene Atlas216508_x_atTonsil366.800214.040Details
BioGPS Gene Atlas216508_x_atTrachea124.850214.040Details
BioGPS Gene Atlas216508_x_atTrigeminalGanglion165.350214.040Details
BioGPS Gene Atlas216508_x_atUterus150.750214.040Details
BioGPS Gene Atlas216508_x_atUterusCorpus120.700214.040Details
BioGPS Gene Atlas216508_x_atWholeBlood186.000214.040Details
BioGPS Gene Atlas216508_x_atWholebrain87.850214.040Details
BioGPS Gene Atlas216508_x_atcolon250.550214.040Details
BioGPS Gene Atlas216508_x_atpineal_day298.740214.040Details
BioGPS Gene Atlas216508_x_atpineal_night244.940214.040Details
BioGPS Gene Atlas216508_x_atretina198.500214.040Details
BioGPS Gene Atlas216508_x_atsmall_intestine349.350214.040Details
BioGPS NCI60216508_x_at7861467.9881739.760Details
BioGPS NCI60216508_x_atA172554.1811739.760Details
BioGPS NCI60216508_x_atA2042455.7951739.760Details
BioGPS NCI60216508_x_atA3611204.3451739.760Details
BioGPS NCI60216508_x_atA4981534.3671739.760Details
BioGPS NCI60216508_x_atA5491347.7821739.760Details
BioGPS NCI60216508_x_atACC31577.9251739.760Details
BioGPS NCI60216508_x_atACHN1476.4231739.760Details
BioGPS NCI60216508_x_atALVA312773.5691739.760Details
BioGPS NCI60216508_x_atCAKI11383.3291739.760Details
BioGPS NCI60216508_x_atCCRT CEM4061.1451739.760Details
BioGPS NCI60216508_x_atCOLO2051775.5951739.760Details
BioGPS NCI60216508_x_atDLD13313.5541739.760Details
BioGPS NCI60216508_x_atDU1451359.8471739.760Details
BioGPS NCI60216508_x_atEKVX1486.8071739.760Details
BioGPS NCI60216508_x_atGM1331633.5091739.760Details
BioGPS NCI60216508_x_atGM16001822.1121739.760Details
BioGPS NCI60216508_x_atGM23131844.4621739.760Details
BioGPS NCI60216508_x_atGM23451954.5601739.760Details
BioGPS NCI60216508_x_atGM24932167.6251739.760Details
BioGPS NCI60216508_x_atGM971659.8761739.760Details
BioGPS NCI60216508_x_atHCC29981467.4881739.760Details
BioGPS NCI60216508_x_atHCT1162248.4151739.760Details
BioGPS NCI60216508_x_atHCT151679.7571739.760Details
BioGPS NCI60216508_x_atHEK 293 T-rex2062.1261739.760Details
BioGPS NCI60216508_x_atHEK 293T1548.9851739.760Details
BioGPS NCI60216508_x_atHEK293916.4031739.760Details
BioGPS NCI60216508_x_atHELA1880.3631739.760Details
BioGPS NCI60216508_x_atHEPG21375.7861739.760Details
BioGPS NCI60216508_x_atHL601605.3661739.760Details
BioGPS NCI60216508_x_atHOP621860.4021739.760Details
BioGPS NCI60216508_x_atHOP92716.0941739.760Details
BioGPS NCI60216508_x_atHS578T1750.9391739.760Details
BioGPS NCI60216508_x_atHSG1089.6201739.760Details
BioGPS NCI60216508_x_atHT10801549.2261739.760Details
BioGPS NCI60216508_x_atHT294497.3731739.760Details
BioGPS NCI60216508_x_atIGROV12060.4541739.760Details
BioGPS NCI60216508_x_atIOSE801591.7051739.760Details
BioGPS NCI60216508_x_atJURKAT3753.2451739.760Details
BioGPS NCI60216508_x_atK5621771.5901739.760Details
BioGPS NCI60216508_x_atKM121952.0231739.760Details
BioGPS NCI60216508_x_atLN18813.1011739.760Details
BioGPS NCI60216508_x_atLNCAP946.9571739.760Details
BioGPS NCI60216508_x_atLOX IMVI1504.6341739.760Details
BioGPS NCI60216508_x_atM142924.5331739.760Details
BioGPS NCI60216508_x_atMALME 3M1074.5581739.760Details
BioGPS NCI60216508_x_atMCF73060.4381739.760Details
BioGPS NCI60216508_x_atMD MB2311443.4751739.760Details
BioGPS NCI60216508_x_atMDA MB435844.7111739.760Details
BioGPS NCI60216508_x_atMOLT43898.1321739.760Details
BioGPS NCI60216508_x_atNCI 4601582.1281739.760Details
BioGPS NCI60216508_x_atNCI H2261300.0641739.760Details
BioGPS NCI60216508_x_atNCI H231316.2271739.760Details
BioGPS NCI60216508_x_atNCI H322M1544.9411739.760Details
BioGPS NCI60216508_x_atNCVADR RES987.2361739.760Details
BioGPS NCI60216508_x_atOVCAR32594.8211739.760Details
BioGPS NCI60216508_x_atOVCAR41423.3201739.760Details
BioGPS NCI60216508_x_atOVCAR51664.2721739.760Details
BioGPS NCI60216508_x_atOVCAR81924.1041739.760Details
BioGPS NCI60216508_x_atPANC11377.8281739.760Details
BioGPS NCI60216508_x_atRL72681.5961739.760Details
BioGPS NCI60216508_x_atRPMI 82261554.6401739.760Details
BioGPS NCI60216508_x_atRS118465003.0401739.760Details
BioGPS NCI60216508_x_atRXF3932132.4831739.760Details
BioGPS NCI60216508_x_atSAOS23218.2561739.760Details
BioGPS NCI60216508_x_atSF2682177.2681739.760Details
BioGPS NCI60216508_x_atSF2951273.9351739.760Details
BioGPS NCI60216508_x_atSF5391545.5291739.760Details
BioGPS NCI60216508_x_atSHSYSY+RA2029.9571739.760Details
BioGPS NCI60216508_x_atSHSYSY-RA1528.3811739.760Details
BioGPS NCI60216508_x_atSKMEL21128.5661739.760Details
BioGPS NCI60216508_x_atSKMEL28697.4061739.760Details
BioGPS NCI60216508_x_atSKMEL5676.1051739.760Details
BioGPS NCI60216508_x_atSKOV3953.5961739.760Details
BioGPS NCI60216508_x_atSN12C1164.4481739.760Details
BioGPS NCI60216508_x_atSNB191352.9421739.760Details
BioGPS NCI60216508_x_atSNB751010.1751739.760Details
BioGPS NCI60216508_x_atSR1897.9171739.760Details
BioGPS NCI60216508_x_atSW6201994.2691739.760Details
BioGPS NCI60216508_x_atT243436.8601739.760Details
BioGPS NCI60216508_x_atT3M43257.4631739.760Details
BioGPS NCI60216508_x_atTK101964.9451739.760Details
BioGPS NCI60216508_x_atU1181081.2831739.760Details
BioGPS NCI60216508_x_atU1381150.6861739.760Details
BioGPS NCI60216508_x_atU20S1948.4771739.760Details
BioGPS NCI60216508_x_atU2511551.3121739.760Details
BioGPS NCI60216508_x_atU87691.2941739.760Details
BioGPS NCI60216508_x_atUACC2571435.1211739.760Details
BioGPS NCI60216508_x_atUACC62783.4931739.760Details
BioGPS NCI60216508_x_atUO312371.5531739.760Details
BioGPS NCI60216508_x_atZR75_11621.8011739.760Details
BioGPS NCI60216508_x_atastrocytes1514.6731739.760Details
BioGPS NCI60216508_x_athuh-71928.0101739.760Details