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Gene ID: 1475 | CSTA Antibody Resource


CSTA Antibody Resource
Gene Full Name: 
cystatin A (stefin A)
Uniprot: 
P01040
Protein Name: 
cystatin-A
Nucleotide: 
NM_005213
Alias: 
AREI;STF1;STFA;
Ensembl: 
ENSG00000121552
Location: 
3q21
HPRD: 
01697
NCBI Gene: 
1475
MIM: 
184600

Summary: 
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008]
Function: 
This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis.
Subcellular location: 
Cytoplasm .
PTM: 
Acetylation;
Disease: 
Ichthyosis, exfoliative, autosomal recessive, ichthyosis bullosa of Siemens-like (AREI) [MIM:607936]: A form of congenital exfoliative ichthyosis, sharing some features with ichthyosis bullosa of Siemens and annular epidermolytic ichthyosis. AREI presents shortly after birth as dry, scaly skin over most of the body with coarse peeling of non-erythematous skin on the palms and soles, which is exacerbated by excessive moisture and minor trauma. Electron microscopy analysis of skin biopsies, reveals mostly normal-appearing upper layers of the epidermis, but prominent intercellular edema of the basal and suprabasal cell layers with aggregates of tonofilaments in the basal keratinocytes. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Protein OPPA00057 CSTA Human - Recombinant Human Cystatin-A 2ug $100 Details
Others OPPA00140 CSTA Human, His - Recombinant Human Cystatin-A His Tag (5ug) 5ug $100 Details
Polyclonal Antibody ARP63647_P050 CSTA Antibody (ARP63647_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig Not tested 50 ug $125 Details
Polyclonal Antibody ARP63648_P050 CSTA Antibody (ARP63648_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB10648 CSTA antibody - C - terminal region (OAAB10648) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAEC01803 Stefin A Antibody (OAEC01803) Human WB, IHC, IF, ELISA 100ug $229 Details
Polyclonal Antibody OAAF01927 CSTA Antibody (OAAF01927) Polyclonal Human WB, IHC, IF, ELISA 100 ug $229 Details

Show all CSTA antibodies


Product Images
CSTA antibody - C - terminal region (OAAB10648) in 293 cells using Western Blot

Sample Type: 293

CSTA antibody - C - terminal region (OAAB10648) in A549 cells using Western Blot

Sample Type: A549

CSTA antibody - C - terminal region (OAAB10648) in Human Skin cells using Immunohistochemistry

Sample Type: Human Skin

CSTA Antibody (OAAF01927) in A549 cells using Western Blot

Sample Type: A549

CSTA Antibody (OAAF01927) in A549 cells using Immunofluorescence

Sample Type: A549

CSTA Antibody (OAAF01927) in Human colon carcinoma cells using Immunohistochemistry

Sample Type: Human colon carcinoma

Stefin A Antibody (OAEC01803) in A549 cells using Western Blot

Sample Type: A549

Stefin A Antibody (OAEC01803) in Human colon carcinoma cells using Immunohistochemistry

Sample Type: Human colon carcinoma


CSTA Protocols

Publications

Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP63648 Bovine CSTA antibody; Bos taurus CSTA antibody F1N608 100.0%
ARP63648 Bovine CSTA antibody; Bos taurus CSTA antibody P80416 100.0%
ARP63647 Bovine CSTA antibody; Bos taurus CSTA antibody F1N608 86.0%
ARP63647 Bovine CSTA antibody; Bos taurus CSTA antibody P80416 86.0%
ARP63648 Cat CSTA antibody; Felis catus CSTA antibody Q8WNR9 100.0%
ARP63647 Chimpanzee CSTA antibody; Pan troglodytes CSTA antibody H2QN77 100.0%
ARP63648 Chimpanzee CSTA antibody; Pan troglodytes CSTA antibody H2QN77 100.0%
ARP63648 Dog CSTA antibody; Canis familiaris CSTA antibody F1PHB6 100.0%
ARP63647 Dog CSTA antibody; Canis familiaris CSTA antibody F1PHB6 86.0%
ARP63648 European domestic ferret CSTA antibody; Mustela putorius furo CSTA antibody M3Y094 100.0%
ARP63648 Giant panda CSTA antibody; Ailuropoda melanoleuca CSTA antibody D2HWU5 100.0%
ARP63647 Giant panda CSTA antibody; Ailuropoda melanoleuca CSTA antibody D2HWU5 79.0%
ARP63648 Horse CSTA antibody; Equus caballus CSTA antibody F6YCC0 92.0%
ARP63647 Horse CSTA antibody; Equus caballus CSTA antibody F6YCC0 79.0%
ARP63647 Human CSTA antibody; Homo sapiens CSTA antibody Q6IB90 100.0%
ARP63648 Human CSTA antibody; Homo sapiens CSTA antibody Q6IB90 100.0%
ARP63648 Human CSTA antibody; Homo sapiens CSTA antibody C9J0E4 100.0%
ARP63647 Human CSTA antibody; Homo sapiens CSTA antibody P01040 100.0%
ARP63648 Human CSTA antibody; Homo sapiens CSTA antibody P01040 100.0%
ARP63648 Rat CSTA antibody; Rattus norvegicus CSTA antibody P01039 79.0%
ARP63647 Rhesus macaque CSTA antibody; Macaca mulatta CSTA antibody F7H310 93.0%
ARP63648 Rhesus macaque CSTA antibody; Macaca mulatta CSTA antibody F7H310 79.0%
ARP63648 Small-eared galago CSTA antibody; Otolemur garnettii CSTA antibody H0XQI4 83.0%
ARP63647 Sumatran orangutan CSTA antibody; Pongo abelii CSTA antibody H2P9K4 93.0%
ARP63648 Sumatran orangutan CSTA antibody; Pongo abelii CSTA antibody H2P9K4 93.0%
ARP63648 Thirteen-lined ground squirrel CSTA antibody; Spermophilus tridecemlineatus CSTA antibody I3N5A4 92.0%
ARP63647 Thirteen-lined ground squirrel CSTA antibody; Spermophilus tridecemlineatus CSTA antibody I3N5A4 79.0%
ARP63647 White-tufted-ear marmoset CSTA antibody; Callithrix jacchus CSTA antibody F7GIC1 86.0%
ARP63648 White-tufted-ear marmoset CSTA antibody; Callithrix jacchus CSTA antibody F7GIC1 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas204971_at721_B_lymphoblasts6.250349.220Details
BioGPS Gene Atlas204971_atAdipocyte11.000349.220Details
BioGPS Gene Atlas204971_atAdrenalCortex5.900349.220Details
BioGPS Gene Atlas204971_atAdrenalgland6.200349.220Details
BioGPS Gene Atlas204971_atAmygdala5.300349.220Details
BioGPS Gene Atlas204971_atAppendix7.000349.220Details
BioGPS Gene Atlas204971_atAtrioventricularNode4.550349.220Details
BioGPS Gene Atlas204971_atBDCA4+_DentriticCells370.150349.220Details
BioGPS Gene Atlas204971_atBonemarrow478.200349.220Details
BioGPS Gene Atlas204971_atBronchialEpithelialCells3874.000349.220Details
BioGPS Gene Atlas204971_atCD105+_Endothelial32.250349.220Details
BioGPS Gene Atlas204971_atCD14+_Monocytes2758.100349.220Details
BioGPS Gene Atlas204971_atCD19+_BCells(neg._sel.)5.900349.220Details
BioGPS Gene Atlas204971_atCD33+_Myeloid2616.350349.220Details
BioGPS Gene Atlas204971_atCD34+198.050349.220Details
BioGPS Gene Atlas204971_atCD4+_Tcells5.400349.220Details
BioGPS Gene Atlas204971_atCD56+_NKCells36.300349.220Details
BioGPS Gene Atlas204971_atCD71+_EarlyErythroid5.550349.220Details
BioGPS Gene Atlas204971_atCD8+_Tcells4.650349.220Details
BioGPS Gene Atlas204971_atCardiacMyocytes8.800349.220Details
BioGPS Gene Atlas204971_atCaudatenucleus4.700349.220Details
BioGPS Gene Atlas204971_atCerebellum4.250349.220Details
BioGPS Gene Atlas204971_atCerebellumPeduncles6.200349.220Details
BioGPS Gene Atlas204971_atCiliaryGanglion5.000349.220Details
BioGPS Gene Atlas204971_atCingulateCortex5.700349.220Details
BioGPS Gene Atlas204971_atColorectaladenocarcinoma5.350349.220Details
BioGPS Gene Atlas204971_atDorsalRootGanglion4.300349.220Details
BioGPS Gene Atlas204971_atFetalThyroid5.750349.220Details
BioGPS Gene Atlas204971_atFetalbrain5.300349.220Details
BioGPS Gene Atlas204971_atFetalliver4.600349.220Details
BioGPS Gene Atlas204971_atFetallung12.650349.220Details
BioGPS Gene Atlas204971_atGlobusPallidus4.050349.220Details
BioGPS Gene Atlas204971_atHeart8.800349.220Details
BioGPS Gene Atlas204971_atHypothalamus5.450349.220Details
BioGPS Gene Atlas204971_atKidney6.150349.220Details
BioGPS Gene Atlas204971_atLeukemia_chronicMyelogenousK-5624.950349.220Details
BioGPS Gene Atlas204971_atLeukemia_promyelocytic-HL-604.700349.220Details
BioGPS Gene Atlas204971_atLeukemialymphoblastic(MOLT-4)4.100349.220Details
BioGPS Gene Atlas204971_atLiver9.050349.220Details
BioGPS Gene Atlas204971_atLung105.900349.220Details
BioGPS Gene Atlas204971_atLymphnode37.800349.220Details
BioGPS Gene Atlas204971_atLymphoma_burkitts(Daudi)23.700349.220Details
BioGPS Gene Atlas204971_atLymphoma_burkitts(Raji)7.750349.220Details
BioGPS Gene Atlas204971_atMedullaOblongata4.700349.220Details
BioGPS Gene Atlas204971_atOccipitalLobe4.700349.220Details
BioGPS Gene Atlas204971_atOlfactoryBulb5.150349.220Details
BioGPS Gene Atlas204971_atOvary14.700349.220Details
BioGPS Gene Atlas204971_atPancreas4.800349.220Details
BioGPS Gene Atlas204971_atPancreaticIslet7.150349.220Details
BioGPS Gene Atlas204971_atParietalLobe6.950349.220Details
BioGPS Gene Atlas204971_atPituitary6.500349.220Details
BioGPS Gene Atlas204971_atPlacenta10.900349.220Details
BioGPS Gene Atlas204971_atPons7.000349.220Details
BioGPS Gene Atlas204971_atPrefrontalCortex6.200349.220Details
BioGPS Gene Atlas204971_atProstate18.200349.220Details
BioGPS Gene Atlas204971_atSalivarygland31.350349.220Details
BioGPS Gene Atlas204971_atSkeletalMuscle11.450349.220Details
BioGPS Gene Atlas204971_atSkin427.000349.220Details
BioGPS Gene Atlas204971_atSmoothMuscle42.700349.220Details
BioGPS Gene Atlas204971_atSpinalcord6.950349.220Details
BioGPS Gene Atlas204971_atSubthalamicNucleus4.900349.220Details
BioGPS Gene Atlas204971_atSuperiorCervicalGanglion6.650349.220Details
BioGPS Gene Atlas204971_atTemporalLobe5.100349.220Details
BioGPS Gene Atlas204971_atTestis4.500349.220Details
BioGPS Gene Atlas204971_atTestisGermCell4.250349.220Details
BioGPS Gene Atlas204971_atTestisIntersitial4.500349.220Details
BioGPS Gene Atlas204971_atTestisLeydigCell5.600349.220Details
BioGPS Gene Atlas204971_atTestisSeminiferousTubule4.450349.220Details
BioGPS Gene Atlas204971_atThalamus5.450349.220Details
BioGPS Gene Atlas204971_atThymus102.800349.220Details
BioGPS Gene Atlas204971_atThyroid7.400349.220Details
BioGPS Gene Atlas204971_atTongue12984.850349.220Details
BioGPS Gene Atlas204971_atTonsil3859.150349.220Details
BioGPS Gene Atlas204971_atTrachea202.150349.220Details
BioGPS Gene Atlas204971_atTrigeminalGanglion8.850349.220Details
BioGPS Gene Atlas204971_atUterus4.250349.220Details
BioGPS Gene Atlas204971_atUterusCorpus7.550349.220Details
BioGPS Gene Atlas204971_atWholeBlood2107.700349.220Details
BioGPS Gene Atlas204971_atWholebrain4.200349.220Details
BioGPS Gene Atlas204971_atcolon5.350349.220Details
BioGPS Gene Atlas204971_atpineal_day6.420349.220Details
BioGPS Gene Atlas204971_atpineal_night6.140349.220Details
BioGPS Gene Atlas204971_atretina6.525349.220Details
BioGPS Gene Atlas204971_atsmall_intestine5.150349.220Details
BioGPS NCI60204971_at7866.00364.610Details
BioGPS NCI60204971_atA1727.33864.610Details
BioGPS NCI60204971_atA2045.68064.610Details
BioGPS NCI60204971_atA3616.17464.610Details
BioGPS NCI60204971_atA49812.27664.610Details
BioGPS NCI60204971_atA5495.91264.610Details
BioGPS NCI60204971_atACC36.44464.610Details
BioGPS NCI60204971_atACHN5.02364.610Details
BioGPS NCI60204971_atALVA316.28464.610Details
BioGPS NCI60204971_atCAKI16.23964.610Details
BioGPS NCI60204971_atCCRT CEM26.52564.610Details
BioGPS NCI60204971_atCOLO2055.88664.610Details
BioGPS NCI60204971_atDLD15.63264.610Details
BioGPS NCI60204971_atDU1455.26664.610Details
BioGPS NCI60204971_atEKVX5.01464.610Details
BioGPS NCI60204971_atGM13343.42964.610Details
BioGPS NCI60204971_atGM16006.08064.610Details
BioGPS NCI60204971_atGM23135.98064.610Details
BioGPS NCI60204971_atGM23455.47164.610Details
BioGPS NCI60204971_atGM24936.19364.610Details
BioGPS NCI60204971_atGM976.94264.610Details
BioGPS NCI60204971_atHCC299828.53064.610Details
BioGPS NCI60204971_atHCT116119.65764.610Details
BioGPS NCI60204971_atHCT154.91364.610Details
BioGPS NCI60204971_atHEK 293 T-rex6.29864.610Details
BioGPS NCI60204971_atHEK 293T5.51264.610Details
BioGPS NCI60204971_atHEK2935.59264.610Details
BioGPS NCI60204971_atHELA4.87764.610Details
BioGPS NCI60204971_atHEPG275.11864.610Details
BioGPS NCI60204971_atHL609.89764.610Details
BioGPS NCI60204971_atHOP625.92164.610Details
BioGPS NCI60204971_atHOP925.03664.610Details
BioGPS NCI60204971_atHS578T66.24864.610Details
BioGPS NCI60204971_atHSG5.79364.610Details
BioGPS NCI60204971_atHT10801898.95964.610Details
BioGPS NCI60204971_atHT296.37664.610Details
BioGPS NCI60204971_atIGROV15.57564.610Details
BioGPS NCI60204971_atIOSE805.71864.610Details
BioGPS NCI60204971_atJURKAT12.05064.610Details
BioGPS NCI60204971_atK56211.82564.610Details
BioGPS NCI60204971_atKM126.21564.610Details
BioGPS NCI60204971_atLN186.56964.610Details
BioGPS NCI60204971_atLNCAP5.73364.610Details
BioGPS NCI60204971_atLOX IMVI42.05964.610Details
BioGPS NCI60204971_atM145.67164.610Details
BioGPS NCI60204971_atMALME 3M10.98764.610Details
BioGPS NCI60204971_atMCF756.77864.610Details
BioGPS NCI60204971_atMD MB2316.86964.610Details
BioGPS NCI60204971_atMDA MB4356.08864.610Details
BioGPS NCI60204971_atMOLT47.28764.610Details
BioGPS NCI60204971_atNCI 4606.79164.610Details
BioGPS NCI60204971_atNCI H22613.15864.610Details
BioGPS NCI60204971_atNCI H235.76164.610Details
BioGPS NCI60204971_atNCI H322M5.69564.610Details
BioGPS NCI60204971_atNCVADR RES5.10864.610Details
BioGPS NCI60204971_atOVCAR36.11864.610Details
BioGPS NCI60204971_atOVCAR45.70364.610Details
BioGPS NCI60204971_atOVCAR55.49064.610Details
BioGPS NCI60204971_atOVCAR84.89764.610Details
BioGPS NCI60204971_atPANC16.74664.610Details
BioGPS NCI60204971_atRL76.76964.610Details
BioGPS NCI60204971_atRPMI 82267.47664.610Details
BioGPS NCI60204971_atRS118466.18764.610Details
BioGPS NCI60204971_atRXF3935.93664.610Details
BioGPS NCI60204971_atSAOS25.79664.610Details
BioGPS NCI60204971_atSF2685.90964.610Details
BioGPS NCI60204971_atSF2955.11564.610Details
BioGPS NCI60204971_atSF5395.08864.610Details
BioGPS NCI60204971_atSHSYSY+RA5.05664.610Details
BioGPS NCI60204971_atSHSYSY-RA5.34364.610Details
BioGPS NCI60204971_atSKMEL2250.81464.610Details
BioGPS NCI60204971_atSKMEL285.91164.610Details
BioGPS NCI60204971_atSKMEL56.15764.610Details
BioGPS NCI60204971_atSKOV36.04864.610Details
BioGPS NCI60204971_atSN12C5.29664.610Details
BioGPS NCI60204971_atSNB194.92264.610Details
BioGPS NCI60204971_atSNB755.19964.610Details
BioGPS NCI60204971_atSR5.95164.610Details
BioGPS NCI60204971_atSW6205.88164.610Details
BioGPS NCI60204971_atT246.47464.610Details
BioGPS NCI60204971_atT3M42972.15864.610Details
BioGPS NCI60204971_atTK105.34464.610Details
BioGPS NCI60204971_atU11847.35864.610Details
BioGPS NCI60204971_atU1385.04464.610Details
BioGPS NCI60204971_atU20S84.08764.610Details
BioGPS NCI60204971_atU2515.49264.610Details
BioGPS NCI60204971_atU87201.05664.610Details
BioGPS NCI60204971_atUACC2575.84264.610Details
BioGPS NCI60204971_atUACC625.95664.610Details
BioGPS NCI60204971_atUO314.86464.610Details
BioGPS NCI60204971_atZR75_130.34964.610Details
BioGPS NCI60204971_atastrocytes5.76464.610Details
BioGPS NCI60204971_athuh-713.47464.610Details